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  Patent History
  • Application
    AT 19960929066T 1996-08-22
  • Publication
    AT 289348 2005-03-15
  Patent Family
Supplementary

published patent: METHODS FOR ENHANCING THE PRODUCTION OF VIRAL VACCINES IN CELL CULTURE BY INTERFERON SUPPRESSION

TitleMETHODS FOR ENHANCING THE PRODUCTION OF VIRAL VACCINES IN CELL CULTURE BY INTERFERON SUPPRESSION
Priority Date1995-08-22 US 08/002621P
1996-08-22 PCT/US1996013745
Inventors
Lau, ASY
Issue Date2005
Citation
Austria Published Patent Application AT 289348. Austria: Austrian Patent Office, 2005 How to Cite?
AbstractMethods for enhancing the production of viral vaccines in animal cell culture are described. These methods rely on the manipulation of the cellular levels of certain interferon induced antiviral activities, in particular, cellular levels of double-stranded RNA (dsRNA) dependent kinase (PKR) and 2'-5' oligoadenylate synthetase (2-5A synthetase). In cell cultures deficient for PKR or 2-5A synthetase, viral yield is enhanced by several orders of magnitude over cell cultures with normal levels of these proteins making these cell cultures useful for the production of viral vaccines.
Persistent Identifierhttp://hdl.handle.net/10722/176516

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:03Z-
dc.date.available2012-11-30T08:38:03Z-
dc.date.issued2005-
dc.identifier.citationAustria Published Patent Application AT 289348. Austria: Austrian Patent Office, 2005en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176516-
dc.description.abstractMethods for enhancing the production of viral vaccines in animal cell culture are described. These methods rely on the manipulation of the cellular levels of certain interferon induced antiviral activities, in particular, cellular levels of double-stranded RNA (dsRNA) dependent kinase (PKR) and 2'-5' oligoadenylate synthetase (2-5A synthetase). In cell cultures deficient for PKR or 2-5A synthetase, viral yield is enhanced by several orders of magnitude over cell cultures with normal levels of these proteins making these cell cultures useful for the production of viral vaccines.en_HK
dc.titleMETHODS FOR ENHANCING THE PRODUCTION OF VIRAL VACCINES IN CELL CULTURE BY INTERFERON SUPPRESSIONen_HK
dc.typePatenten_US
dc.contributor.inventorLau, ASYen_HK
patents.identifier.applicationAT 19960929066Ten_HK
patents.description.assigneeUNIV CALIFORNIA [US]en_HK
patents.description.countryAustriaen_HK
patents.date.publication2005-03-15en_HK
patents.date.application1996-08-22en_HK
patents.date.priority1995-08-22 US 08/002621Pen_HK
patents.date.priority1996-08-22 PCT/US1996013745en_HK
patents.description.ccATen_HK
patents.identifier.publicationAT 289348en_HK
patents.relation.familyAT 289348 (T) 2005-03-15en_HK
patents.relation.familyAU 6860896 (A) 1997-03-19en_HK
patents.relation.familyAU 707130 (B2) 1999-07-01en_HK
patents.relation.familyAU 6857696 (A) 1997-03-19en_HK
patents.relation.familyBR 9610550 (A) 1999-07-06en_HK
patents.relation.familyCA 2229163 (A1) 1997-03-06en_HK
patents.relation.familyCA 2229405 (A1) 1997-03-06en_HK
patents.relation.familyCN 1200148 (A) 1998-11-25en_HK
patents.relation.familyCN 1161469 (C) 2004-08-11en_HK
patents.relation.familyDE 69634360 (T2) 2005-12-29en_HK
patents.relation.familyEP 0846160 (A1) 1998-06-10en_HK
patents.relation.familyEP 0846174 (A1) 1998-06-10en_HK
patents.relation.familyJP H11511324 (A) 1999-10-05en_HK
patents.relation.familyJP 3432519 (B2) 2003-08-04en_HK
patents.relation.familyJP H11514344 (A) 1999-12-07en_HK
patents.relation.familyJP 4267693 (B2) 2009-05-27en_HK
patents.relation.familyMX 9801423 (A) 1998-05-31en_HK
patents.relation.familyUS 5840565 (A) 1998-11-24en_HK
patents.relation.familyUS 6159712 (A) 2000-12-12en_HK
patents.relation.familyUS 6489144 (B1) 2002-12-03en_HK
patents.relation.familyUS 2001001290 (A1) 2001-05-17en_HK
patents.relation.familyUS 6673591 (B2) 2004-01-06en_HK
patents.relation.familyUS 2001001709 (A1) 2001-05-24en_HK
patents.relation.familyUS 6686190 (B2) 2004-02-03en_HK
patents.relation.familyUS 2001055791 (A1) 2001-12-27en_HK
patents.relation.familyUS 6855519 (B2) 2005-02-15en_HK
patents.relation.familyUS 2004157310 (A1) 2004-08-12en_HK
patents.relation.familyUS 7132271 (B2) 2006-11-07en_HK
patents.relation.familyUS 2004219642 (A1) 2004-11-04en_HK
patents.relation.familyWO 9708292 (A1) 1997-03-06en_HK
patents.relation.familyWO 9708324 (A1) 1997-03-06en_HK
patents.description.kindTen_HK
patents.typePatent_publisheden_HK

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