granted patent: Methods For The Identification Of Inhibitors Of Asparagine Synthase As Antibiotics

TitleMethods For The Identification Of Inhibitors Of Asparagine Synthase As Antibiotics
Granted PatentUS 6852484
Granted Date2005-02-08
Priority Date2001-12-10 US 09/012991
Inventors
Issue Date2005
Citation
US Patent 6852484. Washington, DC: US Patent and Trademark Office (USPTO), 2005 How to Cite?
AbstractThe Present Inventors Have Discovered That Asparagine Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Asparagine Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Asparagine Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Asparagine Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.
Persistent Identifierhttp://hdl.handle.net/10722/45689
References

 

DC FieldValueLanguage
dc.date.accessioned2007-10-30T06:32:44Z-
dc.date.available2007-10-30T06:32:44Z-
dc.date.issued2005-
dc.identifier.citationUS Patent 6852484. Washington, DC: US Patent and Trademark Office (USPTO), 2005en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45689-
dc.description.abstractThe Present Inventors Have Discovered That Asparagine Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Asparagine Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Asparagine Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Asparagine Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.en_HK
dc.format.extent1776177 bytes-
dc.format.extent2788 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleMethods For The Identification Of Inhibitors Of Asparagine Synthase As Antibioticsen_HK
dc.typePatenten_HK
dc.description.naturepublished_or_final_version-
dc.contributor.inventorLo, CSCen_HK
dc.contributor.inventorMontenegro-Chamorro, MVen_HK
dc.contributor.inventorFrank, Sen_HK
dc.contributor.inventorDarveaux, Ben_HK
dc.contributor.inventorMahanty, Sen_HK
dc.contributor.inventorHeiniger, Ren_HK
dc.contributor.inventorSkalchunes, Aen_HK
dc.contributor.inventorPan, Hen_HK
dc.contributor.inventorTarper, Ren_HK
dc.contributor.inventorShuster, Jen_HK
dc.contributor.inventorTanzer, MMen_HK
dc.contributor.inventorHamer, Len_HK
dc.contributor.inventorAdachi, Ken_HK
dc.contributor.inventorDeZwaan, TMen_HK
patents.identifier.applicationUS 09/012991en_HK
patents.identifier.grantedUS 6852484en_HK
patents.description.assigneeIcoria Inc [Us]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2003-10-02en_HK
patents.date.granted2005-02-08en_HK
dc.relation.referencesUS 4920109 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920111 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920112 (A) 1990-04-24en_HK
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dc.relation.referencesUS 5976848 (A) 1999-11-02en_HK
dc.relation.referencesUS 6074830 (A) 2000-06-13en_HK
patents.date.application2001-12-10en_HK
patents.date.priority2001-12-10 US 09/012991en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20030186837en_HK
patents.relation.familyAU 2002363978 (A1) 2003-06-23en_HK
patents.relation.familyCA 2469695 (A1) 2003-06-19en_HK
patents.relation.familyEP 1461460 (A2) 2004-09-29en_HK
patents.relation.familyJP 2005524390 (A) 2005-08-18en_HK
patents.relation.familyUS 2003124642 (A1) 2003-07-03en_HK
patents.relation.familyUS 6689578 (B2) 2004-02-10en_HK
patents.relation.familyUS 2003143657 (A1) 2003-07-31en_HK
patents.relation.familyUS 6733963 (B2) 2004-05-11en_HK
patents.relation.familyUS 2003148412 (A1) 2003-08-07en_HK
patents.relation.familyUS 6740498 (B2) 2004-05-25en_HK
patents.relation.familyUS 2003108979 (A1) 2003-06-12en_HK
patents.relation.familyUS 6806060 (B2) 2004-10-19en_HK
patents.relation.familyUS 2003186837 (A1) 2003-10-02en_HK
patents.relation.familyUS 6852484 (B2) 2005-02-08en_HK
patents.relation.familyWO 03050310 (A2) 2003-06-19en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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