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Granted Patent: Methods For The Identification Of Inhibitors Of Homocitrate Synthase As Antibiotics
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TitleMethods For The Identification Of Inhibitors Of Homocitrate Synthase As Antibiotics
 
Granted PatentUS 6632631
 
Granted Date2003-10-14
 
Priority Date2001-11-09 US 09/011200
 
InventorsShuster, J
Tanzer, T
Hamer, L
Adachi, K
DeZwaan, T
Lo, CSC
Montenegro-Chamorro, MV
Frank, S
Darveaux, B
Mahanty, S
Heiniger, R
Skalchunes, A
Pan, H
Tarpey, R
 
Issue Date2003
 
CitationUS Patent 6632631. Washington, DC: US Patent and Trademark Office (USPTO), 2003 [How to Cite?]
 
AbstractThe Present Inventors Have Discovered That Homocitrate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Homocitrate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Homocitrate Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Homocitrate Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.</Ptext>
 
ReferencesUS 4920109 (A) 1990-04-24

US 4920111 (A) 1990-04-24

US 4920112 (A) 1990-04-24

US 4920113 (A) 1990-04-24

US 4921844 (A) 1990-05-01

US 5976848 (A) 1999-11-02

US 6074830 (A) 2000-06-13
 
DC FieldValue
dc.contributor.inventorShuster, J
 
dc.contributor.inventorTanzer, T
 
dc.contributor.inventorHamer, L
 
dc.contributor.inventorAdachi, K
 
dc.contributor.inventorDeZwaan, T
 
dc.contributor.inventorLo, CSC
 
dc.contributor.inventorMontenegro-Chamorro, MV
 
dc.contributor.inventorFrank, S
 
dc.contributor.inventorDarveaux, B
 
dc.contributor.inventorMahanty, S
 
dc.contributor.inventorHeiniger, R
 
dc.contributor.inventorSkalchunes, A
 
dc.contributor.inventorPan, H
 
dc.contributor.inventorTarpey, R
 
dc.date.accessioned2007-10-30T06:32:42Z
 
patents.date.application2001-11-09
 
dc.date.available2007-10-30T06:32:42Z
 
patents.date.granted2003-10-14
 
dc.date.issued2003
 
patents.date.priority2001-11-09 US 09/011200
 
patents.date.publication2003-09-25
 
dc.description.abstractThe Present Inventors Have Discovered That Homocitrate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Homocitrate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Homocitrate Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Homocitrate Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.</Ptext>
 
patents.description.assigneeParadigm Genetics Inc [Us]
 
patents.description.ccUS
 
patents.description.countryUnited States of America
 
patents.description.kindB1
 
dc.description.naturepublished_or_final_version
 
dc.format.extent3078397 bytes
 
dc.format.extent2788 bytes
 
dc.format.mimetypeapplication/pdf
 
dc.format.mimetypetext/plain
 
patents.identifier.applicationUS 09/011200
 
dc.identifier.citationUS Patent 6632631. Washington, DC: US Patent and Trademark Office (USPTO), 2003 [How to Cite?]
 
patents.identifier.grantedUS 6632631
 
patents.identifier.publicationUS 20030180829
 
dc.identifier.urihttp://hdl.handle.net/10722/45688
 
dc.languageeng
 
patents.relation.familyAU 2002365038 (A8) 2003-06-10
 
patents.relation.familyCA 2469772 (A1) 2003-06-05
 
patents.relation.familyEP 1481080 (A2) 2004-12-01
 
patents.relation.familyJP 2005510230 (A) 2005-04-21
 
patents.relation.familyUS 2003180829 (A1) 2003-09-25
 
patents.relation.familyUS 6632631 (B1) 2003-10-14
 
patents.relation.familyUS 2003104511 (A1) 2003-06-05
 
patents.relation.familyUS 6723529 (B2) 2004-04-20
 
patents.relation.familyWO 03046130 (A2) 2003-06-05
 
dc.relation.referencesUS 4920109 (A) 1990-04-24
 
dc.relation.referencesUS 4920111 (A) 1990-04-24
 
dc.relation.referencesUS 4920112 (A) 1990-04-24
 
dc.relation.referencesUS 4920113 (A) 1990-04-24
 
dc.relation.referencesUS 4921844 (A) 1990-05-01
 
dc.relation.referencesUS 5976848 (A) 1999-11-02
 
dc.relation.referencesUS 6074830 (A) 2000-06-13
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents
 
dc.titleMethods For The Identification Of Inhibitors Of Homocitrate Synthase As Antibiotics
 
dc.typePatent
 
patents.typePatent_granted
 
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