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Granted Patent: Methods For The Identification Of Inhibitors Of Alpha-Aminoadipate Reductase As Antibiotics
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TitleMethods For The Identification Of Inhibitors Of Alpha-Aminoadipate Reductase As Antibiotics
 
Granted PatentUS 6723529
 
Granted Date2004-04-20
 
Priority Date2001-11-09 US 09/011146
 
InventorsTanzer, T
Tanzer, MM
Hamer, L
Adachi, K
DeZwaan, T
Lo, CSC
Montenegro-Chamorro, MV
Frank, S
Darveaux, B
Mahanty, S
Heiniger, R
Skalchunes, A
Pan, H
Tarpey, R
Shuster, J
 
CitationUS Patent 6723529. Washington, DC: US Patent and Trademark Office (USPTO), 2004 [How to Cite?]
 
AbstractThe Present Inventors Have Discovered That Alpha-Aminoadipate Reductase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Alpha-Aminoadipate Reductase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Alpha-Aminoadipate Reductase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Alpha-Aminoadipate Reductase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.
 
ReferencesWO 0000643 (A2) 2000-01-06

WO 0000643 (A3) 2000-03-23

US 4920109 (A) 1990-04-24

US 4920111 (A) 1990-04-24

US 4920112 (A) 1990-04-24

US 4920113 (A) 1990-04-24

US 4921844 (A) 1990-05-01

US 5976848 (A) 1999-11-02

US 6074830 (A) 2000-06-13
 
DC FieldValue
dc.contributor.inventorTanzer, T
 
dc.contributor.inventorTanzer, MM
 
dc.contributor.inventorHamer, L
 
dc.contributor.inventorAdachi, K
 
dc.contributor.inventorDeZwaan, T
 
dc.contributor.inventorLo, CSC
 
dc.contributor.inventorMontenegro-Chamorro, MV
 
dc.contributor.inventorFrank, S
 
dc.contributor.inventorDarveaux, B
 
dc.contributor.inventorMahanty, S
 
dc.contributor.inventorHeiniger, R
 
dc.contributor.inventorSkalchunes, A
 
dc.contributor.inventorPan, H
 
dc.contributor.inventorTarpey, R
 
dc.contributor.inventorShuster, J
 
dc.date.accessioned2007-10-30T06:32:39Z
 
patents.date.application2001-11-09
 
dc.date.available2007-10-30T06:32:39Z
 
patents.date.granted2004-04-20
 
patents.date.priority2001-11-09 US 09/011146
 
patents.date.publication2003-06-05
 
dc.description.abstractThe Present Inventors Have Discovered That Alpha-Aminoadipate Reductase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Alpha-Aminoadipate Reductase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Alpha-Aminoadipate Reductase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Alpha-Aminoadipate Reductase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.
 
patents.description.assigneeParadigm Genetics Inc [Us]
 
patents.description.ccUS
 
patents.description.countryUnited States of America
 
patents.description.kindB2
 
dc.description.naturepublished_or_final_version
 
dc.format.extent3233115 bytes
 
dc.format.extent2788 bytes
 
dc.format.mimetypeapplication/pdf
 
dc.format.mimetypetext/plain
 
patents.identifier.applicationUS 09/011146
 
dc.identifier.citationUS Patent 6723529. Washington, DC: US Patent and Trademark Office (USPTO), 2004 [How to Cite?]
 
patents.identifier.grantedUS 6723529
 
patents.identifier.publicationUS 20030104511
 
dc.identifier.urihttp://hdl.handle.net/10722/45686
 
dc.languageeng
 
patents.relation.familyAU 2002365038 (A8) 2003-06-10
 
patents.relation.familyCA 2469772 (A1) 2003-06-05
 
patents.relation.familyEP 1481080 (A2) 2004-12-01
 
patents.relation.familyJP 2005510230 (A) 2005-04-21
 
patents.relation.familyUS 2003180829 (A1) 2003-09-25
 
patents.relation.familyUS 6632631 (B1) 2003-10-14
 
patents.relation.familyUS 2003104511 (A1) 2003-06-05
 
patents.relation.familyUS 6723529 (B2) 2004-04-20
 
patents.relation.familyWO 03046130 (A2) 2003-06-05
 
dc.relation.referencesWO 0000643 (A2) 2000-01-06
 
dc.relation.referencesWO 0000643 (A3) 2000-03-23
 
dc.relation.referencesUS 4920109 (A) 1990-04-24
 
dc.relation.referencesUS 4920111 (A) 1990-04-24
 
dc.relation.referencesUS 4920112 (A) 1990-04-24
 
dc.relation.referencesUS 4920113 (A) 1990-04-24
 
dc.relation.referencesUS 4921844 (A) 1990-05-01
 
dc.relation.referencesUS 5976848 (A) 1999-11-02
 
dc.relation.referencesUS 6074830 (A) 2000-06-13
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents
 
dc.titleMethods For The Identification Of Inhibitors Of Alpha-Aminoadipate Reductase As Antibiotics
 
dc.typePatent
 
patents.typePatent_granted
 
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