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  Patent History
  • Application
    US 09/011146 2001-11-09
  • Publication
    US 2003104511 2003-06-05
  Patent Family
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published patent: Methods for the identification of inhibitors of alpha-aminoadipate reductase as antibiotics

TitleMethods for the identification of inhibitors of alpha-aminoadipate reductase as antibiotics
Priority Date2001-11-09 US 09/011146
Inventors
Tanzer Matthew MShuster JeffreyHamer LisbethAdachi KiichiDezwaan Todd MLo, CSCFrank SherylDarveaux BlaiseMahanty Sanjoy KHeiniger RyanSkalchunes AmyPan HuaqinTarpey RexLo, CSC
Issue Date2003
Citation
US Published patent application US 2003104511. Washington, DC: US Patent and Trademark Office (USPTO), 2003 How to Cite?
AbstractThe present inventors have discovered that alpha-Aminoadipate Reductase is essential for fungal pathogenicity. Specifically, the inhibition of alpha-Aminoadipate Reductase gene expression in fungi results in no signs of successful infection or lesions. Thus, alpha-Aminoadipate Reductase can be used as a target for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit alpha-Aminoadipate Reductase expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals.
Persistent Identifierhttp://hdl.handle.net/10722/176839

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:34Z-
dc.date.available2012-11-30T08:38:34Z-
dc.date.issued2003-
dc.identifier.citationUS Published patent application US 2003104511. Washington, DC: US Patent and Trademark Office (USPTO), 2003en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176839-
dc.description.abstractThe present inventors have discovered that alpha-Aminoadipate Reductase is essential for fungal pathogenicity. Specifically, the inhibition of alpha-Aminoadipate Reductase gene expression in fungi results in no signs of successful infection or lesions. Thus, alpha-Aminoadipate Reductase can be used as a target for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit alpha-Aminoadipate Reductase expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals.en_HK
dc.titleMethods for the identification of inhibitors of alpha-aminoadipate reductase as antibioticsen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorTanzer Matthew Men_HK
dc.contributor.inventorShuster Jeffreyen_HK
dc.contributor.inventorHamer Lisbethen_HK
dc.contributor.inventorAdachi Kiichien_HK
dc.contributor.inventorDezwaan Todd Men_HK
dc.contributor.inventorLo, CSCen_HK
dc.contributor.inventorFrank Sherylen_HK
dc.contributor.inventorDarveaux Blaiseen_HK
dc.contributor.inventorMahanty Sanjoy Ken_HK
dc.contributor.inventorHeiniger Ryanen_HK
dc.contributor.inventorSkalchunes Amyen_HK
dc.contributor.inventorPan Huaqinen_HK
dc.contributor.inventorTarpey Rexen_HK
dc.contributor.inventorLo, CSCen_HK
patents.identifier.applicationUS 09/011146en_HK
patents.description.assigneeTANZER MATTHEW M, ; SHUSTER JEFFREY, ; HAMER LISBETH, ; ADACHI KIICHI, ; DEZWAAN TODD M, ; LO SZE-CHUNG (CLIVE), ; MONTENEGRO-CHAMORRO MARIA VICTORIA, ; FRANK SHERYL, ; DARVEAUX BLAISE, ; MAHANTY SANJOY K, ; HEINIGER RYAN, ; SKALCHUNES AMY, ; PAN HUAQIN, ; TARPEY REX, ; PARADIGM GENETICS, INCen_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2003-06-05en_HK
patents.date.application2001-11-09en_HK
patents.date.priority2001-11-09 US 09/011146en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2003104511en_HK
patents.relation.familyAU 2002365038 (A1) 2003-06-10en_HK
patents.relation.familyCA 2469772 (A1) 2003-06-05en_HK
patents.relation.familyEP 1481080 (A2) 2004-12-01en_HK
patents.relation.familyJP 2005510230 (A) 2005-04-21en_HK
patents.relation.familyUS 2003180829 (A1) 2003-09-25en_HK
patents.relation.familyUS 6632631 (B1) 2003-10-14en_HK
patents.relation.familyUS 2003104511 (A1) 2003-06-05en_HK
patents.relation.familyUS 6723529 (B2) 2004-04-20en_HK
patents.relation.familyWO 03046130 (A2) 2003-06-05en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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