File Download
  Patent History
  • Application
    US 09/010227 2001-12-06
  • Publication
    US 20030143657 2003-07-31
  • Granted
    US 6733963 2004-05-11
  Patent Family
Supplementary

granted patent: Methods For The Identification Of Inhibitors Of 3-Isopropylmalate Dehydratase As Antibiotics

TitleMethods For The Identification Of Inhibitors Of 3-Isopropylmalate Dehydratase As Antibiotics
Granted PatentUS 6733963
Granted Date2004-05-11
Priority Date2001-12-06 US 09/010227
Inventors
Hamer, LAdachi, KDeZwaan, TLo, CSCMontenegro-Chamorro, MVFrank, SDarveaux, BMahanty, SHeiniger, RSkalchunes, APan, HTarpey, RShuster, JTanzer, TTanzer, MM
Issue Date2004
Citation
US Patent 6733963. Washington, DC: US Patent and Trademark Office (USPTO), 2004 How to Cite?
AbstractThe Present Inventors Have Discovered That 3-Isopropylmalate Dehydratase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of 3-Isopropylmalate Dehydratase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, 3-Isopropylmalate Dehydratase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit 3-Isopropylmalate Dehydratase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.
Persistent Identifierhttp://hdl.handle.net/10722/45685
References

 

DC FieldValueLanguage
dc.date.accessioned2007-10-30T06:32:37Z-
dc.date.available2007-10-30T06:32:37Z-
dc.date.issued2004-
dc.identifier.citationUS Patent 6733963. Washington, DC: US Patent and Trademark Office (USPTO), 2004en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45685-
dc.description.abstractThe Present Inventors Have Discovered That 3-Isopropylmalate Dehydratase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of 3-Isopropylmalate Dehydratase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, 3-Isopropylmalate Dehydratase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit 3-Isopropylmalate Dehydratase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.en_HK
dc.format.extent2864719 bytes-
dc.format.extent2788 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.titleMethods For The Identification Of Inhibitors Of 3-Isopropylmalate Dehydratase As Antibioticsen_HK
dc.typePatenten_HK
dc.description.naturepublished_or_final_version-
dc.contributor.inventorHamer, Len_HK
dc.contributor.inventorAdachi, Ken_HK
dc.contributor.inventorDeZwaan, Ten_HK
dc.contributor.inventorLo, CSCen_HK
dc.contributor.inventorMontenegro-Chamorro, MVen_HK
dc.contributor.inventorFrank, Sen_HK
dc.contributor.inventorDarveaux, Ben_HK
dc.contributor.inventorMahanty, Sen_HK
dc.contributor.inventorHeiniger, Ren_HK
dc.contributor.inventorSkalchunes, Aen_HK
dc.contributor.inventorPan, Hen_HK
dc.contributor.inventorTarpey, Ren_HK
dc.contributor.inventorShuster, Jen_HK
dc.contributor.inventorTanzer, Ten_HK
dc.contributor.inventorTanzer, MMen_HK
patents.identifier.applicationUS 09/010227en_HK
patents.identifier.grantedUS 6733963en_HK
patents.description.assigneeParadigm Genetics Inc [Us]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2003-07-31en_HK
patents.date.granted2004-05-11en_HK
dc.relation.referencesUS 5998420 (A) 1999-12-07en_HK
dc.relation.referencesUS 4920109 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920111 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920112 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920113 (A) 1990-04-24en_HK
dc.relation.referencesUS 4921844 (A) 1990-05-01en_HK
dc.relation.referencesUS 5976848 (A) 1999-11-02en_HK
dc.relation.referencesUS 6074830 (A) 2000-06-13en_HK
patents.date.application2001-12-06en_HK
patents.date.priority2001-12-06 US 09/010227en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20030143657en_HK
patents.relation.familyAU 2002363978 (A1) 2003-06-23en_HK
patents.relation.familyCA 2469695 (A1) 2003-06-19en_HK
patents.relation.familyEP 1461460 (A2) 2004-09-29en_HK
patents.relation.familyJP 2005524390 (A) 2005-08-18en_HK
patents.relation.familyUS 2003124642 (A1) 2003-07-03en_HK
patents.relation.familyUS 6689578 (B2) 2004-02-10en_HK
patents.relation.familyUS 2003143657 (A1) 2003-07-31en_HK
patents.relation.familyUS 6733963 (B2) 2004-05-11en_HK
patents.relation.familyUS 2003148412 (A1) 2003-08-07en_HK
patents.relation.familyUS 6740498 (B2) 2004-05-25en_HK
patents.relation.familyUS 2003108979 (A1) 2003-06-12en_HK
patents.relation.familyUS 6806060 (B2) 2004-10-19en_HK
patents.relation.familyUS 2003186837 (A1) 2003-10-02en_HK
patents.relation.familyUS 6852484 (B2) 2005-02-08en_HK
patents.relation.familyWO 03050310 (A2) 2003-06-19en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

Export via OAI-PMH Interface in XML Formats

OR

Export to Other Non-XML Formats