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Patent History
- ApplicationUS 09/007022 2001-12-06
- PublicationUS 2003124642 2003-07-03
Patent Family
- AU 2002363978 (A1) 2003-06-23
- CA 2469695 (A1) 2003-06-19
- EP 1461460 (A2) 2004-09-29
- JP 2005524390 (A) 2005-08-18
- US 2003124642 (A1) 2003-07-03
- US 6689578 (B2) 2004-02-10
- US 2003143657 (A1) 2003-07-31
- US 6733963 (B2) 2004-05-11
- US 2003148412 (A1) 2003-08-07
- US 6740498 (B2) 2004-05-25
- US 2003108979 (A1) 2003-06-12
- US 6806060 (B2) 2004-10-19
- US 2003186837 (A1) 2003-10-02
- US 6852484 (B2) 2005-02-08
- WO 03050310 (A2) 2003-06-19
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published patent: METHODS FOR THE IDENTIFICATION OF INHIBITORS OF 5-AMINOLEVULINATE SYNTHASE AS ANTIBIOTICS
Title | METHODS FOR THE IDENTIFICATION OF INHIBITORS OF 5-AMINOLEVULINATE SYNTHASE AS ANTIBIOTICS |
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Priority Date | 2001-12-06 US 09/007022 |
Inventors | |
Issue Date | 2003 |
Citation | US Published patent application US 2003124642. Washington, DC: US Patent and Trademark Office (USPTO), 2003 How to Cite? |
Abstract | The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, 5-Aminolevulinate synthase can be used as a target for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit 5-Aminolevulinate synthase expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals. |
Persistent Identifier | http://hdl.handle.net/10722/176842 |
DC Field | Value | Language |
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dc.date.accessioned | 2012-11-30T08:38:34Z | - |
dc.date.available | 2012-11-30T08:38:34Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | US Published patent application US 2003124642. Washington, DC: US Patent and Trademark Office (USPTO), 2003 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/176842 | - |
dc.description.abstract | The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, 5-Aminolevulinate synthase can be used as a target for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit 5-Aminolevulinate synthase expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals. | en_HK |
dc.title | METHODS FOR THE IDENTIFICATION OF INHIBITORS OF 5-AMINOLEVULINATE SYNTHASE AS ANTIBIOTICS | en_HK |
dc.type | Patent | en_US |
dc.description.nature | published_or_final_version | en_US |
dc.contributor.inventor | Dezwaan Todd | en_HK |
dc.contributor.inventor | Lo, CSC | en_HK |
dc.contributor.inventor | Frank Sheryl | en_HK |
dc.contributor.inventor | Darveaux Blaise | en_HK |
dc.contributor.inventor | Mahanty Sanjoy K | en_HK |
dc.contributor.inventor | Heiniger Ryan | en_HK |
dc.contributor.inventor | Skalchunes Amy | en_HK |
dc.contributor.inventor | Pan Huaqin | en_HK |
dc.contributor.inventor | Tarpey Rex | en_HK |
dc.contributor.inventor | Shuster Jeffrey | en_HK |
dc.contributor.inventor | Tanzer Matthew M | en_HK |
dc.contributor.inventor | Hamer Lisbeth | en_HK |
dc.contributor.inventor | Adachi Kiichi | en_HK |
patents.identifier.application | US 09/007022 | en_HK |
patents.description.assignee | DEZWAAN TODD, ; LO SZE-CHUNG, ; MONTENEGRO-CHAMARRO MARIA VICTORIA, ; FRANK SHERYL, ; DARVEAUX BLAISE, ; MAHANTY SANJOY K, ; HEINIGER RYAN, ; SKALCHUNES AMY, ; PAN HUAQIN, ; TARPEY REX, ; SHUSTER JEFFREY, ; TANZER MATTHEW M, ; HAMER LISBETH, ; ADACHI KIICHI, ; PARADIGM GENETICS, INC | en_HK |
patents.description.country | United States of America | en_HK |
patents.date.publication | 2003-07-03 | en_HK |
patents.date.application | 2001-12-06 | en_HK |
patents.date.priority | 2001-12-06 US 09/007022 | en_HK |
patents.description.cc | US | en_HK |
patents.identifier.publication | US 2003124642 | en_HK |
patents.relation.family | AU 2002363978 (A1) 2003-06-23 | en_HK |
patents.relation.family | CA 2469695 (A1) 2003-06-19 | en_HK |
patents.relation.family | EP 1461460 (A2) 2004-09-29 | en_HK |
patents.relation.family | JP 2005524390 (A) 2005-08-18 | en_HK |
patents.relation.family | US 2003124642 (A1) 2003-07-03 | en_HK |
patents.relation.family | US 6689578 (B2) 2004-02-10 | en_HK |
patents.relation.family | US 2003143657 (A1) 2003-07-31 | en_HK |
patents.relation.family | US 6733963 (B2) 2004-05-11 | en_HK |
patents.relation.family | US 2003148412 (A1) 2003-08-07 | en_HK |
patents.relation.family | US 6740498 (B2) 2004-05-25 | en_HK |
patents.relation.family | US 2003108979 (A1) 2003-06-12 | en_HK |
patents.relation.family | US 6806060 (B2) 2004-10-19 | en_HK |
patents.relation.family | US 2003186837 (A1) 2003-10-02 | en_HK |
patents.relation.family | US 6852484 (B2) 2005-02-08 | en_HK |
patents.relation.family | WO 03050310 (A2) 2003-06-19 | en_HK |
patents.description.kind | A1 | en_HK |
patents.type | Patent_published | en_HK |