Name Card
Professor Chan, Danny 陳振勝
Title:
S Y and H Y Cheng Professor in Stem Cell Biology and Regenerative Medicine
Professor
Director of Education and Development
Faculty:
Contact Information
Professor Chan, Danny 陳振勝
Title:
S Y and H Y Cheng Professor in Stem Cell Biology and Regenerative Medicine
Professor
Director of Education and Development
Faculty:
Research Interests:(click to check for cognate researchers)
- Role of cellular stress signals in the pathogenesis of osteochondrodysplasias
- Extracellular matrix in stem cell maintenance and differentiation
- Generation and analysis of mouse models with skeletal abnormal abnormalities or intervertebral disc degeneration
- Molecular mechanisms for skeletal patterning: Joint formation and digit patterning
Biography
Graduated from the University of Melbourne, with a Bachelor of Science (degree with honours), Master of Science and PhD, Prof. Chan continued research at his alma mater on heritable skeletal disorders with a focus on extracellular matrix proteins. He joined the University of Hong Kong in 1998, maintaining his research in skeletal biology using mouse as a model to address disease mechanisms in vivo, as well as human genetic studies to define genetic risk factors for common degenerative skeletal conditions such as intervertebral disc degeneration. His research contributed to the molecular understanding of many forms of the human osteochondrodysplasias. In recognition, he was presented with “The Premier’s Award for Health & Medical Research in Victoria, Australia; and more recently, he received the Croucher Senior Fellowship from the Croucher Foundation as recognition of his contribution to skeletal research in Hong Kong.
Honours, Awards & Prizes
| Awardees | Award Date | Honours / Awards / Prizes | Category |
|---|---|---|---|
| 2005-07-04 | The effect of severity of degeneration on mesenchymal stem cells' ability to regenerate the intervetebral disc: a rabbit model: Hansjoerg Wyss Foundation Oral Presentation AwardEuropean Cells and Materials VI / SRN I Spinal Motion Segment: From Basic Science to Clinical Application, July 4-7 2005 | Research Achievement | |
ALADIN, Kaderbatcha Darwesh Mohideen | 2006-09-01 | " Nano Biomechanics Of Type Ii Collagens In Human Intervertebral Discs": Best Paper Award; Conference on Biomedical Engineering, BME 2006. Hong Kong | Research Achievement |
| 2007-06-01 | Linkage analysis on familial early-onset degenerative disc disease.: Best Poster Award. 34th Annual Meeting of International Society for the Study of the Lumbar Spine, Hong Kong. | Research Achievement | |
Chan Li, LC Hung, SC | 2008-01-01 | Best Poster Award
"Age-related degeneration of lumbar intervertebral discs in rabbits revealed by Deuterium Oxide-assisted MRI": World Forum for Spine Research - the intervertebral disc, first Japanese meeting, Kyoto, Japan, January 23-26, 2008 | Research Achievement |
Ng, VCW Chan, WCW | 2007-10-28 | Molecular Basis For Growth Plate Abnormalities In A Mouse Model With Schmid Metaphyseal Chondrodyplasia: Best Poster Award, 7th Pan Pacific Connective Tissue Societies Symposium 2007 - Shangri-La Resort, Cairns, Australia | Research Achievement |
Hui, TY | 2008-01-23 | Best Oral Presentation Award: Collagen-mesenchymal stem cell microspheres for regenerative medicine.: World Forum for Spine Research - the intervertebral disc, first Japanese meeting, Kyoto, Japan, January 23-26, 2008 | Research Achievement |
Hung, SC | 2008-01-01 | Age-related degeneration of lumbar intervertebral disc in rabbit reveal by deuterium oxide-assisted MRI: Best Poster Award, World Forum for Spine Research - the intervertebral disc, first Japanese meeting, Kyoto, Japan, January 23-26, 2008 | Research Achievement |
Tam, V | 2011-03-01 | AOSpine East Asia Research Grant Award: AOSpine East Asia Council | Research Achievement |
TSUI, Yuen Kee SUN, Yi | 2013-04-08 | First prize for poster section: Screen of Small Molecule Compounds for Intervertebral Disc Degeneration by Chemical Genetics.: East meets West Symposium, Shenzhen, China, April 8-9, 2013 | Research Achievement |
CHAN, Cheuk Wing Wilson FENG, Chen | 2013-04-01 | Best Poster Award (poster entitled "Descendents of Lgr5-expressing interzone cells are localized to the superficial layer of the articular cartilage"): Gordon Research Conference 2013: Cartilage Biology & Pathology - Formation, Structure, Function, and Regeneration | Research Achievement |
Kao, PYP | 2013-11-01 | AR Hodgson Award - Prediction of Lumbar Spinal Stenosis in Chinese: Findings from a Genome-wide Association Study: 33rd Annual Congress of The Hong Kong Orthopaedic Association | Research Achievement |
Chan, WCW | 2013-11-01 | Best Oral Presentation (Differentiation and Migration of Endplate Chondrocytes Contribute to the Inner Annulus Fibrosus in
Normal and Degenerative Intervertebral Discs): 9th Pan Pacific Connective Tissue societies Symposium 2014 | Research Achievement |
| 2022-11-01 | 2022 感動香江團體 | Research Achievement | |
Leong, JCY Jim, JJT | 2003-05-13 | Association of lumbar disc degeneration with type IX collagen polymorphisms in Chinese: Best Paper Award: 30th Annual Meeting of ISSLS, Vancouver, Canada, May 13-17, 2003 | Research Achievement |
Leong, JCY | 2007-06-10 | Linkage analysis on familial early-onset degenerative disc disease: Best Poster Award, 34th Annual Meeting of International Society for the Study of the Lumbar Spine, June 10-14, 2007 | Research Achievement |
Tsang, KY Wang, C | 2009-06-01 | Best Poster:
the Roles Of Chop And Gadd34 In The Adaptation Of Hypertrophic Chondrocytes To Er Stress: Gordon Conference (cartilage Biology & Pathology) | Research Achievement |
Hu, J | 2010-10-01 | A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range: Research Output Prize, The University of Hong Kong | Research Achievement |
TAN, Zhijia Melhado, IG Tsang, KY Niu, B | 2011-03-06 | Best Poster Prize: Integration of Factors and Pathways facilitating Chondrocyte Adaptation to ER Stress.: Gordon Conference: Cartilage Biology and Pathology, Ventura, U.S. March 6-11, 2011. | Research Achievement |
Tsang, KY Wang, C Tan, Z | 2012-06-11 | (The Best Poster Award) The role of PERK pathway in adaptation of hypertrophic condrocytes to ER stress: Cold Spring Harbor Asia Meeting on " Bone and Cartilage: from Development to Human Diseases, Suzhou, China, 11-15 June, 2012. | Research Achievement |
Tam, V | 2012-06-01 | Best Short Talk Presentation Award: Can stem cells home to the injured intervertebral disc via intravenous infusion? A murine model: World Forum for Spine Research | Research Achievement |
Ikegawa, S | 2013-05-01 | MacNab/LaRocca Award - Genetic epidemiology of disc degeneration/low back pain: international consortium: International Society for the Study of the Lumbar Spine (ISSLS) | Research Achievement |
SUN, Yi | 2013-04-01 | Best Poster Award " Screen of Small Molecule Compounds for Intervertebral Disc Degeneration by Chemical Genetics": East meets West Symposium, Shenzhen, China, April 8-9, 2013 | Research Achievement |
Li, YY Yeung, CW Diao, H Yuan, M | 2013-10-01 | SYIS-AP Best Oral Presentation Merit: TERMIS-AP Shanghai & Wuzhen, China. October 23-26, 2013 | Research Achievement |
Tam, V Lau, TW Yuen, GWY | 2013-09-01 | Defective TGF beta signaling in bisphosphonates associated atypical femoral diaphyseal fracture: The 3rd Scientific Meeting of the Asian Federation of Osteoporosis Societies | Research Achievement |
LI, Yan | 2014-05-15 | Best Short Talk Award: World Forum for Spine Research - Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation, Xian, PR China, May 15-17, 2014 | Research Achievement |
Karppinen, JI | 2013-11-01 | Best Paper Basic Science Award - Identification of novel serum "metabolomic" biomarkers related to the development of lumbar disc degeneration: 33rd Hong Kong Orthopaedic Association Annual Congress. Hong Kong. | Research Achievement |
Tang, HC YANG, Liu Tsang, KY | 2011-03-01 | Best Poster Prize: Lineage reprogramming of hypertrophic chondrocytes in vivo: Gordon Research Conference on Cartilage Biology & Pathology 2011 | Research Achievement |
ZHOU, Lixiong SUN, Yi Lv, F | 2014-05-01 | Best Participation Award: World Forum for Spine Research, Xian, China, May 2014 | Research Achievement |
KAO, Yu Ping Patrick QIU, Yiyan Ng, FY | 2011-11-01 | Interleukin-1 Beta (il-1b) And Osteoprotegerin (opg) Gene Polymorphisms Are Associated With Knee Osteoarthritis In Chinese: Orthopaedic Basic Science Award, 31st Hong Kong Orthopaedic Association Annual Congress 2011 | Research Achievement |
Aladin Kaderbatcha, DM | 2007-11-17 | Association of Trp2 allele with changes in morphology and nano mechanics of the human intervertebral disc collagens: Best Basic Science Paper Award for Associate Member, 27th Annual Congress of the Hong Kong Orthopaedic Association, Hong Kong, November 17-18, 2007 | Research Achievement |
| 2014-12-01 | 2014 Prize for Best Original Research by Trainees (Gold Medal): Genetic Predisposition of Lumbar Spinal Stenosis in Chinese: ?A Genome-wide Association Study: Hong Kong Academy of Medicine | Research Achievement | |
Tsui, YK | 2007-12-01 | Best Poster Award
"High throughput screening of chemical compounds for the treatment of osteoarthritis": 12th Ressearch Postgraduate Symposium, The University of Hong Kong | Research Achievement |
Tsang, KY | 2016-04-01 | Wiley Blackwell Prize 2016: Development, Growth & Differentiation, John Wiley & Sons, Inc. | Research Achievement |
Professional Societies
| Term Period | Position | Professional Societies |
|---|---|---|
| From 12/2011 | Associate Editor | Journal of Human Genetics |
| from 01/2015 | Coopoerative Editor | Connective Tissue Research |
| from 01/2001 | Oversea Secretary and Member | Australia and New Zealand Society for Matrix Biology |
| From 05/2011 | Member | International Society for Stem Cell Research |
| From 05/2012 | Member | Osteoarthritis Research Society International |
| from 09/2004 | Member | Hong Kong Teacher Association |
| From 03/2013 | Member | International Society for Differentiation |
| from 03/2007 | Member | AOSPINE International |
| from 01/2001 | Member | International Society of Matrix Biology |
| From 07/2010 | Council member | International Society of Matrix Biology |
| from 02/2007 | Member | American Soceity of Human Genetics |
| from 07/2004 | Social Secretary and Member | Hong Kong Society for Developmental Biology |
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