Leung, Victor Yu Leong
Leung, Victor Yu Leong 梁宇亮
- Understanding growth, ageing, and diseases of musculoskeletal system and the interplay among genetic, metabolic, and mechanical factors
- Developing novel biologics and bioengineering approaches to manage skeletal disorders
- Crosstalk of cell senescence, fibrosis, and lipid metabolism in musculoskeletal system
- Oxidative and hypoxic stress mediated skeletal deformity
- Cell adhesion and mechanosensing in joint development and homeostasis
- Joint regeneration using small molecules and biologics
Victor Leung obtained his bachelor's degree in Biochemistry and subsequently PhD in Molecular and Developmental Genetics from The University of Hong Kong under the mentorship of Kathryn Cheah, Ph.D. After graduation he received training under the mentorship of Koichi Masuda, M.D. in the Department of Orthopedic Surgery and Biochemistry, Rush Medical College in Chicago, and later Rocky Tuan, Ph.D. in University of Pittsburgh School of Medicine, specializing in musculoskeletal regeneration and bioengineering. He has been appointed as the Director of the Intervertebral Disc Biology & Regenerative Engineering Program in the department and has been a member of the Stem Cell and Regenerative Medicine Consortium and Centre for Reproduction, Development and Growth of the institute. He is the recipient of Webster Jee Young Investigator Award of the International Chinese Musculoskeletal Research Society (ICMRS) for his contribution to the musculoskeletal research and has received personal and team awards in local and international conferences for research excellence. He served in the committee and topic chair in the Orthopedic Research Society (ORS) meetings. Currently he is an active member of the ORS and AOSpine, and serves on the Editorial Board of JOR Spine.
His research interests focus on understanding the mechanism of spinal degenerative diseases and the associated intervention. Specific areas include molecular and cell biology of the intervertebral disc and regenerativbe strategies for intervertebral disc degeneration in particular using stem cell/ progenitor-based engineering approach. He is also interested in utilizing chemical genetics to identify small molecules to modulate inflammation and proteoglycan metabolism to promote functional restoration of the joints.
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