published patent: CHIMERIC ANTISENSE OF ARABINOFURANOSE ANALOGUE AND DEOXYRIBOSE NUCLEOTIDES

TitleCHIMERIC ANTISENSE OF ARABINOFURANOSE ANALOGUE AND DEOXYRIBOSE NUCLEOTIDES
Priority Date2000-09-06 US 09/230414P
Inventors
Issue Date2002
Citation
WO Published patent application WO 0220773. World Intellectual Property Organization (WIPO), PatentScope, 2002 How to Cite?
AbstractThe present invention relates to novel oligonucleotide chimera used as therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention is directed to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length. Particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc.; More particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to and induce cleavage of (via RNaseH activation) the complementary RNA.
Persistent Identifierhttp://hdl.handle.net/10722/177055

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:39:00Z-
dc.date.available2012-11-30T08:39:00Z-
dc.date.issued2002-
dc.identifier.citationWO Published patent application WO 0220773. World Intellectual Property Organization (WIPO), PatentScope, 2002en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177055-
dc.description.abstractThe present invention relates to novel oligonucleotide chimera used as therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention is directed to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length. Particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc.; More particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to and induce cleavage of (via RNaseH activation) the complementary RNA.en_HK
dc.relation.isreferencedbyUS 2012065249 (A1) 2012-03-15en_HK
dc.relation.isreferencedbyUS 8202851 (B2) 2012-06-19en_HK
dc.relation.isreferencedbyUS 7982028 (B2) 2011-07-19en_HK
dc.relation.isreferencedbyUS 2010048673 (A1) 2010-02-25en_HK
dc.relation.isreferencedbyUS 2011086901 (A9) 2011-04-14en_HK
dc.relation.isreferencedbyUS 8278103 (B2) 2012-10-02en_HK
dc.relation.isreferencedbyUS 2005142535 (A1) 2005-06-30en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleCHIMERIC ANTISENSE OF ARABINOFURANOSE ANALOGUE AND DEOXYRIBOSE NUCLEOTIDESen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorDamha, Masad, Joseen_HK
dc.contributor.inventorParniak, Michael, Aen_HK
dc.contributor.inventorLok, CNen_HK
dc.contributor.inventorViazovkina, Ekaterinaen_HK
patents.identifier.applicationPC T/CA2001001252en_HK
patents.description.assigneeUNIV MCGILL [CA]; DAMHA MASAD JOSE [CA]; PARNIAK MICHAEL A [US]; LOK CHUN NAM [CA]; VIAZOVKINA EKATERINA [CA]en_HK
patents.description.countryWorld Intellectual Property Organization (WIPO)en_HK
patents.date.publication2002-03-14en_HK
patents.date.application2001-09-04en_HK
patents.date.priority2000-09-06 US 09/230414Pen_HK
patents.description.ccWOen_HK
patents.identifier.publicationWO 0220773en_HK
patents.relation.familyAT 293688 (T) 2005-05-15en_HK
patents.relation.familyAU 8944801 (A) 2002-03-22en_HK
patents.relation.familyAU 2001289448 (B2) 2006-03-16en_HK
patents.relation.familyCA 2419563 (A1) 2002-03-14en_HK
patents.relation.familyDE 60110244 (T2) 2006-01-19en_HK
patents.relation.familyEP 1315807 (A2) 2003-06-04en_HK
patents.relation.familyJP 2004507272 (A) 2004-03-11en_HK
patents.relation.familyUS 2004038399 (A1) 2004-02-26en_HK
patents.relation.familyUS 8178348 (B2) 2012-05-15en_HK
patents.relation.familyWO 0220773 (A2) 2002-03-14en_HK
patents.description.kindA2en_HK
patents.typePatent_publisheden_HK

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