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  Patent History
  • Application
    AU 20010089448D 2001-09-04
  • Publication
    AU 8944801 2002-03-22
Supplementary

published patent: Chimeric antisense of arabinofuranose analogue and deoxyribose nucleotides

TitleChimeric antisense of arabinofuranose analogue and deoxyribose nucleotides
Priority Date2001-09-04 PCT/CA2001001252
2000-09-06 US 09/230414P
Inventors
Issue Date2002
Citation
Australia Published Patent Application AU 8944801. Australia: IP Australia, 2002 How to Cite?
AbstractThe present invention relates to novel oligonucleotide chimera used as therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention is directed to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length. Particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc.; More particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to and induce cleavage of (via RNaseH activation) the complementary RNA.
Persistent Identifierhttp://hdl.handle.net/10722/176561

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:07Z-
dc.date.available2012-11-30T08:38:07Z-
dc.date.issued2002-
dc.identifier.citationAustralia Published Patent Application AU 8944801. Australia: IP Australia, 2002en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176561-
dc.description.abstractThe present invention relates to novel oligonucleotide chimera used as therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention is directed to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length. Particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc.; More particularly this invention relates to the use of antisense oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues, flanking a series of deoxyribose nucleotide residues of variable length, to hybridize to and induce cleavage of (via RNaseH activation) the complementary RNA.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleChimeric antisense of arabinofuranose analogue and deoxyribose nucleotidesen_HK
dc.typePatenten_US
dc.contributor.inventorMasad Jose Damhaen_HK
dc.contributor.inventorMichael A. Parniaken_HK
dc.contributor.inventorLok, CNen_HK
dc.contributor.inventorEkaterina Viazovkinaen_HK
patents.identifier.applicationAU 20010089448Den_HK
patents.description.assigneeUNIV MCGILLen_HK
patents.description.countryAustraliaen_HK
patents.date.publication2002-03-22en_HK
patents.date.application2001-09-04en_HK
patents.date.priority2001-09-04 PCT/CA2001001252en_HK
patents.date.priority2000-09-06 US 09/230414Pen_HK
patents.description.ccAUen_HK
patents.identifier.publicationAU 8944801en_HK
patents.relation.familyAT 293688 (T) 2005-05-15en_HK
patents.relation.familyAU 8944801 (A) 2002-03-22en_HK
patents.relation.familyAU 2001289448 (B2) 2006-03-16en_HK
patents.relation.familyCA 2419563 (A1) 2002-03-14en_HK
patents.relation.familyDE 60110244 (T2) 2006-01-19en_HK
patents.relation.familyEP 1315807 (A2) 2003-06-04en_HK
patents.relation.familyJP 2004507272 (A) 2004-03-11en_HK
patents.relation.familyUS 2004038399 (A1) 2004-02-26en_HK
patents.relation.familyUS 8178348 (B2) 2012-05-15en_HK
patents.relation.familyWO 0220773 (A2) 2002-03-14en_HK
patents.description.kindAen_HK
patents.typePatent_publisheden_HK

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