Name Card
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Emeritus Professor Lam, Karen Siu Ling 林小玲

Title:
Honorary Clinical Professor
Director of Clinical Operations, HKU Health System

Principal Investigator
StatusProject CodeProject TitleAmountFunding Year
 
N/AThe Endocrine Society's 88th Annual Meeting Adipocyte Fatty Acid Binding Protein as a Potential Circulating Metabolic Hormone: Clinical and Functional Studies135002005
 
Novel Drugs-HKUEnhancing early phase clinical trials on novel pharmaceutical products in Hong Kong500000002018
 
CFS-HKU5Risk of cardiovascular diseases and related disorders in Hong Kong Chinese: Building on the strength of the Hong Kong Cardiovascular Risk Factors Prevalence Study (1995-2018)74995322018
 
N/AInsulin lispro versus humulin R in Chinese patients with IDDM1200001997
 
HKU 768209MAdipocyte fatty acid binding protein as a novel mediator of obesity-related fatty liver disease7557602009
 
N/ALovastatin in the treatment of diabetics with hypercholesterolaemia and nephropathy - a 2 years prospective study780001989
 
N/AEndocrine function in patients with nasopharyngeal carcinoma (NPC) after external irradiation to the head or head and neck region01982
 
N/AOral DDAVP in cranial diabetes insipidus300001993
 
HKU2/CRF/12RTo Establish a Metabolic Study Centre in Hong Kong: Focusing on the Emerging Metabolic Hormones80000002012
 
HKU 7590/06MAdipocyte fatty acid binding proteins: new mediators of the metabolic syndrome and coronary atherosclerosis17797002006
 
N/AProthrombotic and fibrinolytic factors in NIDDM patients with dyslipidaemia1000001994
 
HKU 762607MDo biomarkers of inflammation and obesity predict the development of hypertension in Hong Kong Chinese?9000392007
 
N/APre-operative shrinkage of macroadenomas using 2-hourly subcutaneous injection of SMS 201-995 in patients with acromegaly500001990
 
N/ARegulation of gene expression of vasoactive intestinal peptide (VIP) in the rat anterior pituitary370001989
 
HKU 7404/04MLinking the metabolic syndrome with progressive atherosclerosis: role of fat-derived hormones9393602004
 
HKU 412/94MNeuroendocrine regulation of growth hormone secretion - effects of glucocorticoids5030001994
 
HKU 7637/05MMacrophage-adipocyte cross-talk in the initiation of obesity-related insulin resistance and type 2 diabetes: role of adiponectin9019572005
 
711027Impaired glucose tolerance as a precursor of diabetes and hypertension in Hong Kong Chinese3163361997
 
HKU 7270/98MInteraction between the polyol pathway and non-enzymatic glycation in the pathogenesis of diabetic nephoropathy7050001998
 
N/ALosartan renal protection study11700001996
 
HKU 7290/97MClinical, biochemical and genetic factors predicting the development of diabetes mellitus and hypertension in Hong Kong Chinese with impaired glucose tolerance3456001997
 
N/AHealth care needs assessment in diabetes500001995
 
N/AAcarbose in Chinese NIDDM patients with secondary sulphonylurea failure1723821993
 
212907Impaired glucose tolerance as a marker for cardiovascular risk6019001999
 
ITS/048/03Adiponectin as a novel diagnostic marker and therapeutic target for the treatment of diabetes, steatohepatitis and other metabolic disorders22889602003
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells621341989
 
HKU 7426/03MClinical, genetic and functional studies of two novel fat-derived hormones6240002003
 
N/ARegulation and function of vasoactive intestinal peptide (VIP) in the rat anterior pituitary499001989
 
INP/027/04Adiponectin as a novel diagnostic marker and therapeutic target for the treatment of diabetes, steatohepatitis and other metabolic disorders1134002004
 
HKU 767208MRole of JNK in adipose tissue inflammation, adipokine production and systemic insulin resistance10165062008
 
HKU 3/CRF/09To Establish a Metabolic Study Center in Hong Kong: Focusing on the liver-derived hormones62000002009
 
HKU 769410MObesity, adipose tissue inflammation and atherosclerosis: role of JNK activation13000002010
 
N/AGenetic and environmental determinants of progressive renal disease and carotid atherosclerosis in Chinese patients with type II diabetes or NIDDM1200001998
 
N/AGenetic and hormonal influences on phenotypic expression of apolipoprotein (a)5000001998
 
N/AMolecular genetics of early onset type 2 diabetes in Chinese1080001999
 
N/ARegulation and function of vasoactive intestinal peptide (VIP) in the rat anterior pituitary250001987
 
N/ARegulation of gene expression of vasoactive intestinal peptide (VIP) in the rat anterior pituitary430001988
 
N/AGlucose tolerance, plasma insulin, C-peptide and glucagon in thyrotoxic patients180001984
 
N/AThe effect of carbimazole on thyroid stimulating immunoglobulin in Graves' Disease60001982
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells50001981
 
N/AEndocrine sequalae of childhood tuberculous meningitis850001989
 
N/AGene expression of hypothalamic releasing hormones1197001992
 
N/APlasma lipoprotein(a) [Lp(a)] in patients with diabetes mellitus and thyroid dysfunction925901993
 
N/AProthrombotic and fibrinolytic factors in diabetic nephropathy1360001995
 
N/APrevention of bone loss induced by inhaled steroid therapy750001996
 
HKU 464/96MHormonal regulation of the pituitary receptors for growth hormone releasing hormone and somatostatin2359001996
 
N/AMolecular genetics of diabetic retinopathy850001997
 
N/AMutational analysis and genotype-phenotype correlation in Chinese patients with multiple endocrine neoplasia type 1950002000
 
N/AGenetics of the metabolic syndrome: central obesity980602001
 
N/AThe role of aldose reductase in the pathogenesis of diabetic nephropathy and atherosclerosis: interaction of polyol pathway with non-enzymatic glycation989002002
 
N/AClinical, genetic and functional studies of two novel fat-derived hormones500002003
 
N/AAutocrine functions of adipokines580002003
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells395001987
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells400001987
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells350001989
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells200001983
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells250001984
 
N/ARegulation of plasminogen activator production and steroidogenesis by rat granulosa cells100001982
 
N/AEndocrine sequalae of childhood tuberculous meningitis75001989
 
N/AGene expression of hypothalamic releasing hormones300001992
 
N/AGene expression of hypothalamic releasing hormones1400001994
 
N/ALinking the metabolic syndrome with progressive atherosclerosis: role of fat-derived hormones500002003
 
N/ARegulation and function of vasoactive intestinal peptide (VIP) in the rat anterior pituitary400001989
 
N/ARegulation of gene expression of vasoactive intestinal peptide (VIP) in the rat anterior pituitary1500001991
 
N/AThe effect of carbimazole on thyroid stimulating immunoglobulin in Graves' Disease200001987
 
N/AThe effect of carbimazole on thyroid stimulating immunoglobulin in Graves' Disease30001984
 
N/AApplication for seed fund for the strategic theme on healthy ageing10000002004
 
HKU 7637/05MMacrophage-adipocyte cross-talk in the initiation of obesity-related insulin resistance and type 2 diabetes: role of adiponectin500002005
 
200507176039Human ANGPTL4 Gene: Molecular Scanning and Evaluation of Association with Insulin Resistance and Type 2 diabetes in Chinese529202005
 
200711159082Role of adipocyte-fatty acid binding protein (A-FABP) in the development of non-alcoholic steatohepatitis (NASH)1060002007
 
N/AHealthy Ageing15000002008
 
200811159079Clinical implications of genetic variants of the newly discovered type 2 diabetes susceptibility genes in Southern Chinese700002008
 
CTC-HKUEstablishing a Phase 1 Clinical Trials Centre in Queen Mary Hospital: Extending Hong Kong's Competitive Edges in Healthcare, Education and Life Sciences Research and Development400000002013
 
N/AAgeing15000002013
Co-Investigator
StatusProject CodeProject TitleAmountFunding Year
 
21222081Risks and burdens of metabolic sequelae in long COVID: focusing on glucose, lipid and bone metabolism14938072022
 
20211971Fragility fractures in type 2 diabetes as an emerging diabetic complication: epidemiology, burden and strategies of primary prevention6782482022
 
N/APrevalence of psychological and psychiatric morbidity in a juvenile diabetic clinic and a cardiac arrhythmia clinic01990
 
N/AGrowth hormone treatment of short stature in Chinese patients with [beta]-thalassaemia major. An opern self-controlled study1440001990
 
N/ATwo proposals on the use of Sign Test of testing the median in the presence of ties02001
 
HKU 7486/04MCharacterization of the receptor and postreceptor events that underlie the anti-atherogenic and anti-diabetic actions of adiponectin14145302004
 
N_HKU 727/05The use of adiponectin as a biomarker to identify novel anti-diabetic and anti-atherogenic agents from Chinese herbs7840002005
 
06172266Exploring the role of microRNA in sight-threatening diabetic retinopathy in Chinese patients with type 2 diabetes14999562018
 
HKU4/CRF/10A Multi-disciplinary Approach to Investigate Vascular Dysfunction in Obesity and Diabetes: From Molecular Mechanism to Therapeutic Intervention63300002010
 
204218Establishment of a comprehensive service and registry for hereditary familial endocrinopathy syndromes in Hong Kong10487712004
 
17125916Metabolic determinants of fibrosis reversal in advanced chronic hepatitis B during long-term nucleoside analogue therapy7682282016
 
06070951A population-based prospective study to investigate the associations of obesity and adipokines with the incidence of cardiovascular disease and cancer7716002007
 
06171646A randomized, open-label, parallel-group study to determine the efficacy of sequential high-intensity focused ultrasound (HIFU) ablation versus fixed-dose radioiodine-131 therapy in moderate-sized non-toxic multinodular goiter7709402018
 
203205A dementia outreach programme in Central, Western and Southern districts of Hong Kong6508192003
 
N/ATreatment of growth hormone deficient dwarfs with growth hormone releasing hormone (GRH) and the effect of antithyroid drug therapy in pregnant thyrotoxic patients on thyroid function in the neonates500001987
 
AoE/M-707/18Institute of Metabolic Medicine496890002018
 
201411159145Validating the Diabetes Risk Score (DRS) app to detect persons at risk of diabetes in Hong Kong Chinese population566252014
 
HKU 7609/05MAngiopoitein-like protein 4 (ANGPTL4) as a novel therapeutic target for the treatment of insulin resistance and hyperglycemia14580402005
 
HKU 2/07CVascular dysfunction in obesity and diabetes: from risk prediction to therapeutic intervention55000002007
 
HKU 763312MDoes an elevated lipocalin-2 concentration in plasma lead to endothelial dysfunction and hypertension?11588942012
 
T12-705/11Personalized Medicine for Cardiovascular Diseases: From Genomic Testing and Biomarkers to Human Pluripotent Stem Cell Platform337050002011
 
12132941A prospective randomized study on health-related quality of life of patients with incidental small (<2cm) asymptomatic thyroid nodules and cost-effectiveness analysis in managing small incidental thyroid nodules6791602014
 
ITS/099/07A noninvasive method to estimate variation of blood glucose levels using metabolic measurements4726502007
 
N/AMolecular defect in Chinese patients with congenital adrenal hyperplasia01990
 
HKU 785611MMechanism and Reversibility of Myocardial Fibrosis in Patients with Diabetic Cardiomyopathy: Role of Aliskiren.9500002011
 
N_HKU726/14Fatty acid binding protein-4 as a mediator of autoimmune diabetes: from molecular mechanism to clinical significance10989112014
 
HKU 7645/06MHypoxia inducible factor 1&alpha; as a mediator of obesity-induced chronic inflammation, aberrant production of adipokines, and insulin resistance8435002006
 
HKU 7248/00MBody mass index, adiposity, serum leptin and insulin sensitivity in Chinese and Caucasians: a comparative study9372002000
 
HKU 7229/01MHong Kong cardiovascular risk factor prevalence study-2 (CRISPS-2)11000002001
 
C7055-14GA Multi-disciplinary Approach to Investigate Vascular Dysfunction in Obesity and Diabetes: From Molecular Mechanism to Therapeutic Intervention87808502014
 
N/AEndocrine function in patients with nasopharyngeal carcinoma (NPC) after external irradiation to the head and neck region1023201984
 
N/AA new long-acting dopamine agonist CV205-502 for the treatment of hyperprolactinaemia in patients resistant to parlodel01987
 
N/AApolipoproteins genetic variations - role in atherosclerosis460001992
 
HKU 780210MBiomarkers of Obesity-related Cardiometaolic Risks in Chinese6094452010
 
HKU 483/96MThe roles of oxidised LDL and advanced glycosylation end products in the pathogenesis of endothelial dysfunction in diabetes mellitus5620001996
 
N_HKU 735/08Adipocyte fatty acid binding protein as a novel diagnostic marker and therapeutic target to combat vascular complications of diabetes: mechanisms and clinical implications7120002008
 
A-HKU705/13The gut microbiota-adipose tissue axis in the pathogenesis of obesity and its related metabolic disorders: molecular mechanism and clinical implications26309762013
 
17118119Identification of novel susceptibility loci for diabetic retinopathy in Chinese patients with type 2 diabetes: an Asian Screening Array analysis11152282019
 
GHP/027/05Development of a Suspension Antibody Array-based Multiplex Immunoassay for Early Diagnosis and Therapeutic Monitoring of Diabetes and Cardiovascular Diseases28990452005
 
14150781Adipocyte fatty acid binding protein as a novel marker of the development of sight threatening diabetic retinopathy7708562016
 
08193216Metabolomics signature for the prediction of diabetic kidney disease in Chinese patients with type 2 diabetes14938202020
 
03144016Impact of genetic variants identified in genome-wide association studies and their possible interaction with hypertension on the risk of diabetic retinopathy9405042015
 
19200931The effect of simvastatin on bone density in postmenopausal women with type 2 diabetes: a double-blind, randomized, active-comparator (ezetimibe) controlled clinical trial14783932021
 
04150716A randomized, open-label, parallel-group study to explore the efficacy of high-intensity focused ultrasound (HIFU) versus fixed-dose radioiodine-131 in the treatment of relapsed Graves’ disease8820202016
 
N/ATreatment of growth hormone deficient dwarfs with growth hormone releasing hormone (GRH) and the effect of antithyroid drug therapy in pregnant thyrotoxic patients on thyroid function in the neonates344821989
 
HKU 407/94MGenetic and hormonal influences on phenotypic expression of apolipoprotein (a)5030001994
 
N/AHormonal and genetic interactions in apolipoprotein(a) phenotypic expression250001994
 
02132836FGF21 resistance as a potential mediator of systemic insulin resistance and type 2 diabetes9997362014