Validating the Diabetes Risk Score (DRS) app to detect persons at risk of diabetes in Hong Kong Chinese population
Dr Leung, Yee Man Angela (Principal investigator)
diabetes, at risk group, mobile app, Chinese, prevention, validation
Block Grant Earmarked for Research (104)
HKU Project Code
Seed Funding Programme for Basic Research
Different DRS have been developed for different populations, for example, Finnish Diabetes Risk Score (FINDRISC)3 for Finnish population, Dundee Coronary Risk Score for English people4, Australian Screening Protocol for Australians4. A recent review concluded that Finnish Diabetes Risk Score (FINDRISC) tool as the best available tool for use in clinical practice due to its simple, fast, inexpensive and non-invasive features4. It was concluded that age, BMI, waist circumference, use of blood pressure medication, history of high blood glucose, physical activity less than 4 hours per week, daily consumption of vegetables or fruits could predict the 10-year risk of diabetes3. FINDRISC has good sensitivity (=0.78), specificity (=0.77) and positive predictive value (=0.13)3. FINDRISC ranges from 0 to 26, and 15 or more is considered as high risk of diabetes in Finnish population5. FINDRISC is considered as a laymen-friendly tool because all the measures can be reported by laymen, and no laboratory data is involved. It is originally designed as a simple paper-and-pencil screening tool that could be used by laymen without training5. Recent study showed that FINDRISC was also the tool for screening different types of pre-diabetes (impaired fasting glucose, impaired glucose tolerance and undetected diabetes)6. FINDRISC is now being used in various European countries including Netherland, France, Italy and Spain. Nonetheless, the application of this tool in Chinese population has never been investigated and the cut-off score of this scale in Chinese population is uncertain. The proliferation of smartphones and its software applications (or apps) has provided a new channel for health promotion. The advantage and convenience of compact size and mobility of smartphones allows users to access health information and tools at any time and at any place that best suits individuals’ pace of living. A research found that 75 million adults in USA used their smartphones for health information and tools7. Among those aged 55 and older who own smartphones or tablets, half of them are using the devices for health purposes7. These apps are designed for clinical assessment, symptom monitoring, health education, resource location, tracking treatment progress, skills training, and two-way communication with health providers8. A wide array of common topic areas such as smoking cessation, sexual and reproductive health, mental health are covered for people of all ages9. A recent systematic review showed that as at 19 June 2012, seven free-of-charge app for assessing the risk of type 2 diabetes were identified, and among these, four used the FINDRISC10 as the logarithm for calculating the risk score, and yet, it has been criticized that FINDRISC was developed for a specific population and when we extrapolating the score to other populations such as Chinese population, validation of the risk score is needed10. In addition, since mobile app can calculate the risk score immediately, a more complex model other than the existing formula used in FINDRISC can be applied10. Thus, it is worthy to develop a modified logarithm for mobile app application based on FINDRISC original logarithm and Chinese people’s lifestyle. The objectives of the proposed study are: to valid the FINDRISC score in Chinese population; and 2) to modify the logarithm of the risk score based on Chinese people’s lifestyle.