published patent: Oral Dna Composition For Hepatitis B Virus Chronic Infection

TitleOral Dna Composition For Hepatitis B Virus Chronic Infection
Priority Date2006-04-27 US 11/411844
2003-02-28 US 10/375143
2002-02-28 US 10/359945P
Inventors
Issue Date2006
Citation
US Published patent application 20060228374. Washington, DC: US Patent and Trademark Office (USPTO), 2006 How to Cite?
AbstractThe Present Invention Provides An Oral Dna Composition For Improving An Impaired Immunity Associated With Chronic Infection Of Hepatitis B Virus (Hbv) And For Suppressing Transgene Expression For A Protrated Period Of Time Comprising An Attenuated Strain Of Bacterial Cells Which Preferentially Target Phagocytic Cells Of The Intestinal Mucosa, And Which Serve As A Vehicle For A Plasmid Vector Carrying One Or More Genes Or Complementary Dna Coding For At Least A Portion Of A Hepatitis B Viral Protein Or Peptide. Given Orally, The Dna Composition Causes A Transient And Self-Limiting Infection Of The Intestinal Tract Through Autolysis Of The Bacterial Cells And Release Of The Plasmid After Gaining Entry Into Infected Host Cells. A Promotor Contained Within The Plasmid Allows For Expression Of The Hbv Gene(S) In The Eurokaryotic Environment, The Viral Products Of Which Help To Booster A Cell-Mediated Immunity To Clear The Infection And Reverse A State Of Immune Tolerance Characteristic Of Hbv Chronic Infection.
Persistent Identifierhttp://hdl.handle.net/10722/46932

 

DC FieldValueLanguage
dc.date.accessioned2007-10-30T07:01:35Z-
dc.date.available2007-10-30T07:01:35Z-
dc.date.issued2006-
dc.identifier.citationUS Published patent application 20060228374. Washington, DC: US Patent and Trademark Office (USPTO), 2006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/46932-
dc.description.abstractThe Present Invention Provides An Oral Dna Composition For Improving An Impaired Immunity Associated With Chronic Infection Of Hepatitis B Virus (Hbv) And For Suppressing Transgene Expression For A Protrated Period Of Time Comprising An Attenuated Strain Of Bacterial Cells Which Preferentially Target Phagocytic Cells Of The Intestinal Mucosa, And Which Serve As A Vehicle For A Plasmid Vector Carrying One Or More Genes Or Complementary Dna Coding For At Least A Portion Of A Hepatitis B Viral Protein Or Peptide. Given Orally, The Dna Composition Causes A Transient And Self-Limiting Infection Of The Intestinal Tract Through Autolysis Of The Bacterial Cells And Release Of The Plasmid After Gaining Entry Into Infected Host Cells. A Promotor Contained Within The Plasmid Allows For Expression Of The Hbv Gene(S) In The Eurokaryotic Environment, The Viral Products Of Which Help To Booster A Cell-Mediated Immunity To Clear The Infection And Reverse A State Of Immune Tolerance Characteristic Of Hbv Chronic Infection.en_HK
dc.format.extent4610414 bytes-
dc.format.extent2458 bytes-
dc.format.extent2150 bytes-
dc.format.extent7189 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.format.mimetypetext/plain-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleOral Dna Composition For Hepatitis B Virus Chronic Infectionen_HK
dc.typePatenten_HK
dc.description.naturepublished_or_final_versionen_HK
dc.contributor.inventorNg, MHen_HK
dc.contributor.inventorYuen, KYen_HK
dc.contributor.inventorZheng, BJen_HK
patents.identifier.applicationUS 11/411844en_HK
patents.description.assigneeUniv Hong Kongen_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2006-10-12en_HK
patents.date.application2006-04-27en_HK
patents.date.priority2006-04-27 US 11/411844en_HK
patents.date.priority2003-02-28 US 10/375143en_HK
patents.date.priority2002-02-28 US 10/359945Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20060228374en_HK
patents.relation.familyAU 2003210122 (A8) 2003-09-09en_HK
patents.relation.familyCA 2380471 (A1) 2003-08-28en_HK
patents.relation.familyCN 1444996 (A) 2003-10-01en_HK
patents.relation.familyCN 100528238 (C) 2009-08-19en_HK
patents.relation.familyHK 1058144 (A1) 2010-04-23en_HK
patents.relation.familyUS 2003162741 (A1) 2003-08-28en_HK
patents.relation.familyUS 2006228374 (A1) 2006-10-12en_HK
patents.relation.familyWO 03072012 (A2) 2003-09-04en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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