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  Patent History
  • Application
    US 11/004399 2004-12-03
  • Publication
    US 2006053516 2006-03-09

published patent: Genetically Modified Plants Comprising Sars-Cov Viral Nucleotide Sequences And Methods Of Use Thereof For Immunization Against Sars

TitleGenetically Modified Plants Comprising Sars-Cov Viral Nucleotide Sequences And Methods Of Use Thereof For Immunization Against Sars
Priority Date2004-12-03 US 11/004399
2003-12-05 US 10/527637P
Inventors
Issue Date2006
Citation
US Published patent application 2006053516. Washington, DC: US Patent and Trademark Office (USPTO), 2006 How to Cite?
AbstractThe Invention Relates To Genetically Modified Plants And Progeny Thereof Which Constitute Edible Plant-Derived Mucosal Vaccines And Injectable Plant-Derived Mucosal Vaccines Against Severe Acute Respiratory Syndrome (Sars). The Invention Relates To A Recombinant Vector That Transforms Specifically, But Not Limited To, The Nuclei And/Or Plastids Of Tobacco, Tomato And Lettuce Plants For Antigen Production. In Specific Embodiments, The Plastid Transformation Vector Expressing The Nucleotide Sequences Are Pcv1, Pcv6 And Pcv8, And Their Derivatives Containing An S1 With Nucleotide (But Not Amino Acid) Changes To Optimize Codon Usage For Expression In Plants. The Present Invention Relates To Methods Of Making The Modified Plants Which Comprises Transformation Of Plants With Vectors For Nuclear Expression And/Or Plastid Expression Of Nucleotide Sequences Of The Sars-Cov Virus, Fragments, Derivatives, Analogs, Or Variants Thereof. The Present Invention Also Relates To Methods Of Immunization Against Sars And Methods Of Antibody Detection Using The Sars-Cov Antigens Generated By The Plastid And/Or Nuclear Vector(S) Transformed Plants.
Persistent Identifierhttp://hdl.handle.net/10722/45683

 

DC FieldValueLanguage
dc.date.accessioned2007-10-30T06:32:34Z-
dc.date.available2007-10-30T06:32:34Z-
dc.date.issued2006-
dc.identifier.citationUS Published patent application 2006053516. Washington, DC: US Patent and Trademark Office (USPTO), 2006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45683-
dc.description.abstractThe Invention Relates To Genetically Modified Plants And Progeny Thereof Which Constitute Edible Plant-Derived Mucosal Vaccines And Injectable Plant-Derived Mucosal Vaccines Against Severe Acute Respiratory Syndrome (Sars). The Invention Relates To A Recombinant Vector That Transforms Specifically, But Not Limited To, The Nuclei And/Or Plastids Of Tobacco, Tomato And Lettuce Plants For Antigen Production. In Specific Embodiments, The Plastid Transformation Vector Expressing The Nucleotide Sequences Are Pcv1, Pcv6 And Pcv8, And Their Derivatives Containing An S1 With Nucleotide (But Not Amino Acid) Changes To Optimize Codon Usage For Expression In Plants. The Present Invention Relates To Methods Of Making The Modified Plants Which Comprises Transformation Of Plants With Vectors For Nuclear Expression And/Or Plastid Expression Of Nucleotide Sequences Of The Sars-Cov Virus, Fragments, Derivatives, Analogs, Or Variants Thereof. The Present Invention Also Relates To Methods Of Immunization Against Sars And Methods Of Antibody Detection Using The Sars-Cov Antigens Generated By The Plastid And/Or Nuclear Vector(S) Transformed Plants.en_HK
dc.format.extent21370069 bytes-
dc.format.extent111311 bytes-
dc.format.extent2395 bytes-
dc.format.extent2407 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.relation.isreferencedbyWO 2008151215 (A1) 2008-12-11en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleGenetically Modified Plants Comprising Sars-Cov Viral Nucleotide Sequences And Methods Of Use Thereof For Immunization Against Sarsen_HK
dc.typePatenten_HK
dc.description.naturepublished_or_final_versionen_HK
dc.contributor.inventorChye, MLen_HK
dc.contributor.inventorLi, HYen_HK
dc.contributor.inventorRamalingam, Sen_HK
dc.contributor.inventorPoon, LLMen_HK
dc.contributor.inventorPeiris, JSMen_HK
patents.identifier.applicationUS 11/004399en_HK
patents.description.assigneeUniv Hong Kongen_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2006-03-09en_HK
patents.date.application2004-12-03en_HK
patents.date.priority2004-12-03 US 11/004399en_HK
patents.date.priority2003-12-05 US 10/527637Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2006053516en_HK
patents.relation.familyCN 1906302 (A) 2007-01-31en_HK
patents.relation.familyUS 2006053516 (A1) 2006-03-09en_HK
patents.relation.familyWO 2005054473 (A1) 2005-06-16en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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