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  Patent History
  • Application
    US 12/417672 2009-04-03
  • Granted
    US 8114904 2009-10-08
Supplementary

granted patent: LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES

TitleLUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES
Granted PatentUS 8114904
US 20090253118
Granted Date2009-10-08
Priority Date2009-04-03 US 12/417672
2008-04-05 US 12/042720P
Inventors
Issue Date2009
Citation
US Patent US 20090253118. Washington, DC: US Patent and Trademark Office (USPTO), 2009 How to Cite?
AbstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.
Persistent Identifierhttp://hdl.handle.net/10722/210510

 

DC FieldValueLanguage
dc.date.accessioned2015-06-17T07:03:28Z-
dc.date.available2015-06-17T07:03:28Z-
dc.date.issued2009-
dc.identifier.citationUS Patent US 20090253118. Washington, DC: US Patent and Trademark Office (USPTO), 2009-
dc.identifier.urihttp://hdl.handle.net/10722/210510-
dc.description.abstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.-
dc.relation.isreferencedbyUS 2013196362 (A1) 2013-08-01-
dc.relation.isreferencedbyUS 2012122136 (A1) 2012-05-17 -
dc.relation.isreferencedby U S8828678 (B2) 2014-09-09-
dc.relation.isreferencedbyCN 102382641 (A) 2012-03-21 -
dc.relation.isreferencedby C N102382641 (B) 2013-07-24-
dc.relation.isreferencedbyWO 2012074693 (A1) 2012-06-07-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleLUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES-
dc.typePatent-
dc.identifier.authorityYANG DAN=rp00825-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorPENG TAO-
dc.contributor.inventorYANG DAN-
patents.identifier.applicationUS 12/417672-
patents.identifier.grantedUS 8114904-
patents.identifier.grantedUS 20090253118-
patents.description.assigneeVERSITECH LTD [CN]; MORNINGSIDE VENTURES LTD [CN] -
patents.description.countryUnited States of America -
patents.date.granted2009-10-08-
patents.identifier.hkutechidChm-2008-00279-1-
patents.date.application2009-04-03-
patents.date.priority2009-04-03 US 12/417672-
patents.date.priority2008-04-05 US 12/042720P-
patents.description.ccus-
patents.relation.familyCN 101983202 (A) 2011-03-02 -
patents.relation.family U S8114904 (B2) 2012-02-14-
patents.relation.familyEP 2250177 (A1) 2010-11-17 -
patents.relation.familyJP 2011516432 (A) 2011-05-26-
patents.relation.familyWO 2009121247 (A1) 2009-10-08-
patents.description.kindA1-
patents.typePatent_granted-

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