File Download
  Patent History
  • Application
    CN 20098112013 2009-04-07
  • Publication
    CN 101983202 2011-03-02
Supplementary

Patent: Luminescence quenchers and fluorogenic probes for detection of reactive species

TitleLuminescence quenchers and fluorogenic probes for detection of reactive species
Priority Date2008-04-05 US 12/042720P
2009-04-07 PCT/CN2009000376
Inventors
Issue Date2011
Citation
China Published Patent Application CN 101983202. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2011 How to Cite?
AbstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.
Persistent Identifierhttp://hdl.handle.net/10722/210500

 

DC FieldValueLanguage
dc.date.accessioned2015-06-17T07:03:07Z-
dc.date.available2015-06-17T07:03:07Z-
dc.date.issued2011-
dc.identifier.citationChina Published Patent Application CN 101983202. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2011-
dc.identifier.urihttp://hdl.handle.net/10722/210500-
dc.description.abstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.-
dc.relation.isreferencedbyC N102807543 (B) 2014-12-10-
dc.relation.isreferencedbyCN 102212054 (A) 2011-10-12-
dc.relation.isreferencedbyC N102212054 (B) 2013-12-11-
dc.relation.isreferencedbyWO 2013113279 (A1) 2013-08-08-
dc.relation.isreferencedbyCN 102807543 (A) 2012-12-05-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleLuminescence quenchers and fluorogenic probes for detection of reactive species-
dc.typePatent-
dc.identifier.authorityYANG DAN=rp00825-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorPENG TAO-
dc.contributor.inventorYANG DAN-
patents.identifier.applicationCN 20098112013-
patents.identifier.applicationZL200980112013.5-
patents.description.assigneeVERSITECH LTD; MORNINGSIDE VENTURES LTD-
patents.description.countryChina, PRC-
patents.date.publication2011-03-02-
patents.identifier.hkutechidChm-2008-00279-7-
patents.identifier.hkutechidChm-2008-00279-8-
patents.date.application2009-04-07-
patents.date.priority2008-04-05 US 12/042720P-
patents.date.priority2009-04-07 PCT/CN2009000376-
patents.description.cccn-
patents.identifier.publicationCN 101983202-
patents.relation.familyWO 2009121247 (A1) 2009-10-08-
patents.relation.familyUS 2009253118 (A1) 2009-10-08-
patents.relation.familyJP 2011516432 (A) 2011-05-26-
patents.relation.familyU S8114904 (B2) 2012-02-14-
patents.relation.familyEP 2250177 (A1) 2010-11-17-
patents.description.kindA-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats