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  Patent History
  • Application
    JP 20110502215 2009-04-07
  • Granted
    JP 2011516432 2011-05-26
Supplementary

granted patent: LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES

TitleLUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES
Granted PatentJP 2011516432
Granted Date2011-05-26
Priority Date2008-04-05 US 12/042720P
2009-04-07 PCT/CN2009000376
Inventors
Issue Date2016
Citation
Japan Published Patent JP 5882054. Tokyo, Japan: Japan Patent Office (JPO), 2016 How to Cite?
AbstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.
Persistent Identifierhttp://hdl.handle.net/10722/228258
References

 

DC FieldValueLanguage
dc.date.accessioned2016-08-03T01:33:23Z-
dc.date.available2016-08-03T01:33:23Z-
dc.date.issued2016-
dc.identifier.citationJapan Published Patent JP 5882054. Tokyo, Japan: Japan Patent Office (JPO), 2016-
dc.identifier.urihttp://hdl.handle.net/10722/228258-
dc.description.abstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleLUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES-
dc.typePatent-
dc.identifier.authorityYang, Dan=rp00825-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorPeng, Tao-
dc.contributor.inventorYang, Dan-
patents.identifier.applicationJP 20110502215-
patents.identifier.grantedJP 2011516432-
patents.description.countryJapan -
patents.date.granted2011-05-26-
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patents.date.application2009-04-07-
patents.date.priority2008-04-05 US 12/042720P-
patents.date.priority2009-04-07 PCT/CN2009000376-
patents.description.ccjp-
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patents.description.kindA-
patents.typePatent_granted-

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