Patent History
  • Application
    EP 20090728917 2009-04-07
  • Granted
    EP 2250177 2010-11-17
Supplementary

granted patent: LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES

TitleLUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES
Granted PatentEP 2250177
Granted Date2010-11-17
Priority Date2009-04-07 PCT/CN2009000376
2008-04-05 US 12/042720P
Inventors
Issue Date2010
Citation
EP Patent EP 2250177. European Patent Office (EPO), Escapenet, 2010 How to Cite?
AbstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.
Persistent Identifierhttp://hdl.handle.net/10722/210519
References

 

DC FieldValueLanguage
dc.date.accessioned2015-06-17T07:03:46Z-
dc.date.available2015-06-17T07:03:46Z-
dc.date.issued2010-
dc.identifier.citationEP Patent EP 2250177. European Patent Office (EPO), Escapenet, 2010-
dc.identifier.urihttp://hdl.handle.net/10722/210519-
dc.description.abstractProvided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleLUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES-
dc.typePatent-
dc.identifier.authorityYANG, DAN=rp00825-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorPENG, TAO-
dc.contributor.inventorYANG, DAN-
patents.identifier.applicationEP 20090728917-
patents.identifier.grantedEP 2250177-
patents.description.assigneeVERSITECH LTD [CN]; MORNINGSIDE VENTURES LTD [CN]-
patents.description.countryEuropean Patent Office-
patents.date.granted2010-11-17-
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patents.typePatent_granted-

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