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  Patent History
  • Application
    PC T/CN2003001020 2003-12-01
  • Publication
    WO 2004050873 2004-06-17

published patent: GENETICALLY MODIFIED PLANTS EXPRESSING PROTEINASE INHIBITORS, SAPINA2A OR SAPIN2B, AND METHODS OF USE THEREOF FOR THE INHIBITION OF TRYPSIN-AND CHYMOTRYPSIN-LIKE ACTIVITIES

TitleGENETICALLY MODIFIED PLANTS EXPRESSING PROTEINASE INHIBITORS, SAPINA2A OR SAPIN2B, AND METHODS OF USE THEREOF FOR THE INHIBITION OF TRYPSIN-AND CHYMOTRYPSIN-LIKE ACTIVITIES
Priority Date2002-11-29 US 10/429992P
Inventors
Issue Date2004
Citation
WO Published patent application WO 2004050873. World Intellectual Property Organization (WIPO), PatentScope, 2004 How to Cite?
AbstractThe present invention relates to proteinase inhibitor II genes, SaPIN2a and SaPIN2b, their production in transformed plants, and isolation of SaPIN2a and SaPIN2b proteins from transformed plants of the invention. The invention further relates to use in inhibiting endogenous protease activities in transformed plants. In specific embodiments, the protease activities are trypsin-like and chymotrypsin-like activities. The invention relates to a method for protection of heterologous protein production in transformed plants by the co-expression of a proteinase inhibitor gene, e.g. SaPIN2a or SaPIN2b, which encodes a proteinase inhibitor protein, or a biologically active fragment, analog, and variant thereof, that inhibits protease activities. Specifically, the present invention also provides methods of inhibiting programmed cell death, including senescence, in plants. The invention further relates to methods to enhance resistance of plants to pests or pathogens, including insects. The present invention also relates to genetically modified plants, and in particular genetically modified lettuce. The genetically modified plants have inhibited endogenous trypsin-like and chymotrypsin-like activities following transformation of the plant with a vector comprising one or more proteinase inhibitor II gene, such as SaPIN2a and/or SaPIN2b. The invention further relates to transformed plants having enhanced resistance to insects. The invention further relates to transformed plants in which PCD or senescense is inhibited by transformation of plants using vectors of the present invention.
Persistent Identifierhttp://hdl.handle.net/10722/177077

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:39:03Z-
dc.date.available2012-11-30T08:39:03Z-
dc.date.issued2004-
dc.identifier.citationWO Published patent application WO 2004050873. World Intellectual Property Organization (WIPO), PatentScope, 2004en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177077-
dc.description.abstractThe present invention relates to proteinase inhibitor II genes, SaPIN2a and SaPIN2b, their production in transformed plants, and isolation of SaPIN2a and SaPIN2b proteins from transformed plants of the invention. The invention further relates to use in inhibiting endogenous protease activities in transformed plants. In specific embodiments, the protease activities are trypsin-like and chymotrypsin-like activities. The invention relates to a method for protection of heterologous protein production in transformed plants by the co-expression of a proteinase inhibitor gene, e.g. SaPIN2a or SaPIN2b, which encodes a proteinase inhibitor protein, or a biologically active fragment, analog, and variant thereof, that inhibits protease activities. Specifically, the present invention also provides methods of inhibiting programmed cell death, including senescence, in plants. The invention further relates to methods to enhance resistance of plants to pests or pathogens, including insects. The present invention also relates to genetically modified plants, and in particular genetically modified lettuce. The genetically modified plants have inhibited endogenous trypsin-like and chymotrypsin-like activities following transformation of the plant with a vector comprising one or more proteinase inhibitor II gene, such as SaPIN2a and/or SaPIN2b. The invention further relates to transformed plants having enhanced resistance to insects. The invention further relates to transformed plants in which PCD or senescense is inhibited by transformation of plants using vectors of the present invention.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleGENETICALLY MODIFIED PLANTS EXPRESSING PROTEINASE INHIBITORS, SAPINA2A OR SAPIN2B, AND METHODS OF USE THEREOF FOR THE INHIBITION OF TRYPSIN-AND CHYMOTRYPSIN-LIKE ACTIVITIESen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorChye, MLen_HK
dc.contributor.inventorXu, Zengfuen_HK
dc.contributor.inventorSin, Sukfongen_HK
patents.identifier.applicationPC T/CN2003001020en_HK
patents.description.assigneeUNIV HONG KONG [CN]en_HK
patents.description.countryWorld Intellectual Property Organization (WIPO)en_HK
patents.date.publication2004-06-17en_HK
patents.date.application2003-12-01en_HK
patents.date.priority2002-11-29 US 10/429992Pen_HK
patents.description.ccWOen_HK
patents.identifier.publicationWO 2004050873en_HK
patents.relation.familyAU 2003286088 (A1) 2004-06-23en_HK
patents.relation.familyUS 2004205846 (A1) 2004-10-14en_HK
patents.relation.familyUS 7256327 (B2) 2007-08-14en_HK
patents.relation.familyWO 2004050873 (A1) 2004-06-17en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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