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  Patent History
  • Application
    US 10/725829 2003-12-01
  • Publication
    US 2004205846 2004-10-14

published patent: Genetically modified plants expressing proteinase inhibitors, SaPIN2a or SaPIN2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities

TitleGenetically modified plants expressing proteinase inhibitors, SaPIN2a or SaPIN2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities
Priority Date2003-12-01 US 10/725829
2002-11-29 US 10/429992P
Inventors
Issue Date2004
Citation
US Published patent application US 2004205846. Washington, DC: US Patent and Trademark Office (USPTO), 2004 How to Cite?
AbstractThe present invention relates to proteinase inhibitor II genes, SaPIN2a and SaPIN2b, their production in transformed plants, and isolation of SaPIN2a and SaPIN2b proteins from transformed plants of the invention. The invention further relates to use in inhibiting endogenous protease activities in transformed plants. In specific embodiments, the protease activities are trypsin-like and chymotrypsin-like activities. The invention relates to a method for protection of heterologous protein production in transformed plants by the co-expression of a proteinase inhibitor gene, e.g. SaPIN2a or SaPIN2b, which encodes a proteinase inhibitor protein, or a biologically active fragment, analog, and variant thereof, that inhibits protease activities. Specifically, the present invention also provides methods of inhibiting programmed cell death, including senescence, in plants.; The invention further relates to methods to enhance resistance of plants to pests or pathogens, including insects. The present invention also relates to genetically modified plants, and in particular genetically modified lettuce. The genetically modified plants have inhibited endogenous trypsin-like and chymotrypsin-like activities following transformation of the plant with a vector comprising one or more proteinase inhibitor II gene, such as SaPIN2a and/or SaPIN2b. The invention further relates to transformed plants having enhanced resistance to insects. The invention further relates to transformed plants in which PCD or senescense is inhibited by transformation of plants using vectors of the present invention.
Persistent Identifierhttp://hdl.handle.net/10722/176870

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:39Z-
dc.date.available2012-11-30T08:38:39Z-
dc.date.issued2004-
dc.identifier.citationUS Published patent application US 2004205846. Washington, DC: US Patent and Trademark Office (USPTO), 2004en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176870-
dc.description.abstractThe present invention relates to proteinase inhibitor II genes, SaPIN2a and SaPIN2b, their production in transformed plants, and isolation of SaPIN2a and SaPIN2b proteins from transformed plants of the invention. The invention further relates to use in inhibiting endogenous protease activities in transformed plants. In specific embodiments, the protease activities are trypsin-like and chymotrypsin-like activities. The invention relates to a method for protection of heterologous protein production in transformed plants by the co-expression of a proteinase inhibitor gene, e.g. SaPIN2a or SaPIN2b, which encodes a proteinase inhibitor protein, or a biologically active fragment, analog, and variant thereof, that inhibits protease activities. Specifically, the present invention also provides methods of inhibiting programmed cell death, including senescence, in plants.; The invention further relates to methods to enhance resistance of plants to pests or pathogens, including insects. The present invention also relates to genetically modified plants, and in particular genetically modified lettuce. The genetically modified plants have inhibited endogenous trypsin-like and chymotrypsin-like activities following transformation of the plant with a vector comprising one or more proteinase inhibitor II gene, such as SaPIN2a and/or SaPIN2b. The invention further relates to transformed plants having enhanced resistance to insects. The invention further relates to transformed plants in which PCD or senescense is inhibited by transformation of plants using vectors of the present invention.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleGenetically modified plants expressing proteinase inhibitors, SaPIN2a or SaPIN2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activitiesen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorChye, MLen_HK
dc.contributor.inventorXu Zeng-Fuen_HK
dc.contributor.inventorSin Suk-Fongen_HK
patents.identifier.applicationUS 10/725829en_HK
patents.description.assigneeCHYE MEE LEN, ; XU ZENG-FU, ; SIN SUK-FONG, ; THE UNIVERSITY OF HONG KONGen_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2004-10-14en_HK
patents.date.application2003-12-01en_HK
patents.date.priority2003-12-01 US 10/725829en_HK
patents.date.priority2002-11-29 US 10/429992Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 2004205846en_HK
patents.relation.familyAU 2003286088 (A1) 2004-06-23en_HK
patents.relation.familyUS 2004205846 (A1) 2004-10-14en_HK
patents.relation.familyUS 7256327 (B2) 2007-08-14en_HK
patents.relation.familyWO 2004050873 (A1) 2004-06-17en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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