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  Patent History
  • Application
    US 10/725829 2003-12-01
  • Publication
    US 20040205846 2004-10-14
  • Granted
    US 7256327 2007-08-14

granted patent: Genetically Modified Plants Expressing Proteinase Inhibitors, Sapin2a Or Sapin2b, And Methods Of Use Thereof For The Inhibition Of Trypsin- And Chymotrypsin-Like Activities

TitleGenetically Modified Plants Expressing Proteinase Inhibitors, Sapin2a Or Sapin2b, And Methods Of Use Thereof For The Inhibition Of Trypsin- And Chymotrypsin-Like Activities
Granted PatentUS 7256327
Granted Date2007-08-14
Priority Date2003-12-01 US 10/725829
2002-11-29 US 10/429992P
Inventors
Issue Date2007
Citation
US Patent 7256327. Washington, DC: US Patent and Trademark Office (USPTO), 2007 How to Cite?
AbstractThe Present Invention Relates To Proteinase Inhibitor Ii Genes, Sapin2a And Sapin2b, Their Production In Transformed Plants, And Isolation Of Sapin2a And Sapin2b Proteins From Transformed Plants Of The Invention. The Invention Further Relates To Use In Inhibiting Endogenous Protease Activities In Transformed Plants. In Specific Embodiments, The Protease Activities Are Trypsin-Like And Chymotrypsin-Like Activities. The Invention Relates To A Method For Protection Of Heterologous Protein Production In Transformed Plants By The Co-Expression Of A Proteinase Inhibitor Gene, E.G. Sapin2a Or Sapin2b, Which Encodes A Proteinase Inhibitor Protein, Or A Biologically Active Fragment, Analog, And Variant Thereof, That Inhibits Protease Activities. Specifically, The Present Invention Also Provides Methods Of Inhibiting Programmed Cell Death, Including Senescence, In Plants.; The Invention Further Relates To Methods To Enhance Resistance Of Plants To Pests Or Pathogens, Including Insects. The Present Invention Also Relates To Genetically Modified Plants, And In Particular Genetically Modified Lettuce. The Genetically Modified Plants Have Inhibited Endogenous Trypsin-Like And Chymotrypsin-Like Activities Following Transformation Of The Plant With A Vector Comprising One Or More Proteinase Inhibitor Ii Gene, Such As Sapin2a And/Or Sapin2b. The Invention Further Relates To Transformed Plants Having Enhanced Resistance To Insects. The Invention Further Relates To Transformed Plants In Which Pcd Or Senescense Is Inhibited By Transformation Of Plants Using Vectors Of The Present Invention.
Persistent Identifierhttp://hdl.handle.net/10722/142224
References

 

DC FieldValueLanguage
dc.date.accessioned2011-10-19T06:35:42Z-
dc.date.available2011-10-19T06:35:42Z-
dc.date.issued2007-
dc.identifier.citationUS Patent 7256327. Washington, DC: US Patent and Trademark Office (USPTO), 2007en_HK
dc.identifier.urihttp://hdl.handle.net/10722/142224-
dc.description.abstractThe Present Invention Relates To Proteinase Inhibitor Ii Genes, Sapin2a And Sapin2b, Their Production In Transformed Plants, And Isolation Of Sapin2a And Sapin2b Proteins From Transformed Plants Of The Invention. The Invention Further Relates To Use In Inhibiting Endogenous Protease Activities In Transformed Plants. In Specific Embodiments, The Protease Activities Are Trypsin-Like And Chymotrypsin-Like Activities. The Invention Relates To A Method For Protection Of Heterologous Protein Production In Transformed Plants By The Co-Expression Of A Proteinase Inhibitor Gene, E.G. Sapin2a Or Sapin2b, Which Encodes A Proteinase Inhibitor Protein, Or A Biologically Active Fragment, Analog, And Variant Thereof, That Inhibits Protease Activities. Specifically, The Present Invention Also Provides Methods Of Inhibiting Programmed Cell Death, Including Senescence, In Plants.; The Invention Further Relates To Methods To Enhance Resistance Of Plants To Pests Or Pathogens, Including Insects. The Present Invention Also Relates To Genetically Modified Plants, And In Particular Genetically Modified Lettuce. The Genetically Modified Plants Have Inhibited Endogenous Trypsin-Like And Chymotrypsin-Like Activities Following Transformation Of The Plant With A Vector Comprising One Or More Proteinase Inhibitor Ii Gene, Such As Sapin2a And/Or Sapin2b. The Invention Further Relates To Transformed Plants Having Enhanced Resistance To Insects. The Invention Further Relates To Transformed Plants In Which Pcd Or Senescense Is Inhibited By Transformation Of Plants Using Vectors Of The Present Invention.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleGenetically Modified Plants Expressing Proteinase Inhibitors, Sapin2a Or Sapin2b, And Methods Of Use Thereof For The Inhibition Of Trypsin- And Chymotrypsin-Like Activitiesen_HK
dc.typePatenten_US
dc.identifier.emailChye, Mee Len:mlchye@hkucc.hku.hken_US
dc.identifier.emailSin, Suk Fong:en_US
dc.identifier.authorityChye, Mee Len=rp00687en_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorChye, Mee Lenen_US
dc.contributor.inventorSin, Suk Fongen_US
patents.identifier.applicationUS 10/725829en_HK
patents.identifier.grantedUS 7256327en_HK
patents.description.assigneeUniv Hong Kong [Cn]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2004-10-14en_HK
patents.date.granted2007-08-14en_HK
dc.relation.referencesUS 6031087 (A) 2000-02-29en_HK
dc.relation.referencesUS 2003041353 (A1) 2003-02-27en_HK
dc.relation.referencesUS 2004210966 (A1) 2004-10-21en_HK
dc.relation.referencesUS 7294506 (B2) 2007-11-13en_HK
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dc.relation.referencesWO 0142441 (A2) 2001-06-14en_HK
dc.relation.referencesWO 0142441 (A3) 2002-01-03en_HK
patents.identifier.hkutechidBotany-2002-00089-1en_US
patents.date.application2003-12-01en_HK
patents.date.priority2003-12-01 US 10/725829en_HK
patents.date.priority2002-11-29 US 10/429992Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20040205846en_HK
patents.relation.familyAU 2003286088 (A1) 2004-06-23en_HK
patents.relation.familyUS 2004205846 (A1) 2004-10-14en_HK
patents.relation.familyUS 7256327 (B2) 2007-08-14en_HK
patents.relation.familyWO 2004050873 (A1) 2004-06-17en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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