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  Patent History
  • Application
    EP 20060704231 2006-02-01
  • Publication
    EP 1846004 2007-10-24
Supplementary

published patent: NEW USES OF DINUCLEOTIDE POLYPHOSPHATE DERIVATIVES

TitleNEW USES OF DINUCLEOTIDE POLYPHOSPHATE DERIVATIVES
Priority Date2006-02-01 PCT/GB2006000343
2005-02-03 GB20050002250
Inventors
Issue Date2007
Citation
EP Published Patent application EP 1846004. European Patent Office (EPO), Escapenet, 2007 How to Cite?
AbstractThe present invention provides the use of analogues and derivatives of dinucleoside polyphosphates with formula (I) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in one or more of: the treatment of ischemia, inducing ischemic tolerance, modulating cerebral ischemia, to delay the onset of a hypoxic depolarisation stage when ischemic events are initiated; as a neurological protection agent; as a tissue protection agent; the treatment of pain; and the treatment of inflammation, wherein X, is selected from wherein X<1> and X<2> are independently selected from H, Cl, Br and F; each Y is independently selected from S and O; each Z is independently selected from -CX<3>X<4>-,-NH-,-O- ; wherein X<3> and X<4 >are selected from H, CI, Br and F; B1 and B2 are independently selected from adenine, guanine, xanthine, thymine, uracil, cytosine and inosine; S1 and S2 are independently selected from ribose, open chain ribose, 2'-deoxyribose, 3'deoxyribose and arabinofuranoside. V is selected from 0, 1 , 2, 3, 4 and 5; W is selected from 0, 1 , 2, 3, 4 and 5; and V plus W is an integer from 2 to 6.
Persistent Identifierhttp://hdl.handle.net/10722/176750
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:26Z-
dc.date.available2012-11-30T08:38:26Z-
dc.date.issued2007-
dc.identifier.citationEP Published Patent application EP 1846004. European Patent Office (EPO), Escapenet, 2007en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176750-
dc.description.abstractThe present invention provides the use of analogues and derivatives of dinucleoside polyphosphates with formula (I) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in one or more of: the treatment of ischemia, inducing ischemic tolerance, modulating cerebral ischemia, to delay the onset of a hypoxic depolarisation stage when ischemic events are initiated; as a neurological protection agent; as a tissue protection agent; the treatment of pain; and the treatment of inflammation, wherein X, is selected from wherein X<1> and X<2> are independently selected from H, Cl, Br and F; each Y is independently selected from S and O; each Z is independently selected from -CX<3>X<4>-,-NH-,-O- ; wherein X<3> and X<4 >are selected from H, CI, Br and F; B1 and B2 are independently selected from adenine, guanine, xanthine, thymine, uracil, cytosine and inosine; S1 and S2 are independently selected from ribose, open chain ribose, 2'-deoxyribose, 3'deoxyribose and arabinofuranoside. V is selected from 0, 1 , 2, 3, 4 and 5; W is selected from 0, 1 , 2, 3, 4 and 5; and V plus W is an integer from 2 to 6.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleNEW USES OF DINUCLEOTIDE POLYPHOSPHATE DERIVATIVESen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorMiller, Andrew Daviden_HK
dc.contributor.inventorWright, Michaelen_HK
dc.contributor.inventorLozovaya, Natalyaen_HK
dc.contributor.inventorTanner, JAen_HK
patents.identifier.applicationEP 20060704231en_HK
patents.description.assigneeIMUTHES LTD [GB]en_HK
patents.description.countryEuropean Patent Officeen_HK
patents.date.publication2007-10-24en_HK
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patents.date.application2006-02-01en_HK
patents.date.priority2006-02-01 PCT/GB2006000343en_HK
patents.date.priority2005-02-03 GB20050002250en_HK
patents.description.ccEPen_HK
patents.identifier.publicationEP 1846004en_HK
patents.relation.familyAU 2006210715 (A1) 2006-08-10en_HK
patents.relation.familyCA 2596959 (A1) 2006-08-10en_HK
patents.relation.familyCN 101180066 (A) 2008-05-14en_HK
patents.relation.familyEP 1846004 (A1) 2007-10-24en_HK
patents.relation.familyJP 2008528665 (A) 2008-07-31en_HK
patents.relation.familyUS 2008319184 (A1) 2008-12-25en_HK
patents.relation.familyWO 2006082397 (A1) 2006-08-10en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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