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  Patent History
  • Application
    CN 20068009069 2006-02-01
  • Publication
    CN 101180066 2008-05-14
Supplementary

published patent: New uses of dinucleotide polyphosphate derivatives

TitleNew uses of dinucleotide polyphosphate derivatives
Priority Date2005-02-03 GB20050002250
Inventors
Issue Date2008
Citation
China Published Patent Application CN 101180066. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2008 How to Cite?
AbstractThe present invention provides the use of analogues and derivatives of dinucleoside polyphosphates with formula (I) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in one or more of: the treatment of ischemia, inducing ischemic tolerance, modulating cerebral ischemia, to delay the onset of a hypoxic depolarisation stage when ischemic events are initiated; as a neurological protection agent; as a tissue protection agent; the treatment of pain; and the treatment of inflammation, wherein X, is selected from wherein X<1> and X<2> are independently selected from H, Cl, Br and F; each Y is independently selected from S and O; each Z is independently selected from -CX<3>X<4>-,-NH-,-O- ; wherein X<3> and X<4 >are selected from H, CI, Br and F; B1 and B2 are independently selected from adenine, guanine, xanthine, thymine, uracil, cytosine and inosine; S1 and S2 are independently selected from ribose, open chain ribose, 2'-deoxyribose, 3'deoxyribose and arabinofuranoside. V is selected from 0, 1 , 2, 3, 4 and 5; W is selected from 0, 1 , 2, 3, 4 and 5; and V plus W is an integer from 2 to 6.
Persistent Identifierhttp://hdl.handle.net/10722/176610

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:13Z-
dc.date.available2012-11-30T08:38:13Z-
dc.date.issued2008-
dc.identifier.citationChina Published Patent Application CN 101180066. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2008en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176610-
dc.description.abstractThe present invention provides the use of analogues and derivatives of dinucleoside polyphosphates with formula (I) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in one or more of: the treatment of ischemia, inducing ischemic tolerance, modulating cerebral ischemia, to delay the onset of a hypoxic depolarisation stage when ischemic events are initiated; as a neurological protection agent; as a tissue protection agent; the treatment of pain; and the treatment of inflammation, wherein X, is selected from wherein X<1> and X<2> are independently selected from H, Cl, Br and F; each Y is independently selected from S and O; each Z is independently selected from -CX<3>X<4>-,-NH-,-O- ; wherein X<3> and X<4 >are selected from H, CI, Br and F; B1 and B2 are independently selected from adenine, guanine, xanthine, thymine, uracil, cytosine and inosine; S1 and S2 are independently selected from ribose, open chain ribose, 2'-deoxyribose, 3'deoxyribose and arabinofuranoside. V is selected from 0, 1 , 2, 3, 4 and 5; W is selected from 0, 1 , 2, 3, 4 and 5; and V plus W is an integer from 2 to 6.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleNew uses of dinucleotide polyphosphate derivativesen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorMiller Andrew Daviden_HK
dc.contributor.inventorWright Michaelen_HK
dc.contributor.inventorTanner, JAen_HK
dc.contributor.inventorLozovaya Natalyaen_HK
patents.identifier.applicationCN 20068009069en_HK
patents.description.assigneeIC VEC LTD [GB]en_HK
patents.description.countryChina, PRCen_HK
patents.date.publication2008-05-14en_HK
patents.date.application2006-02-01en_HK
patents.date.priority2005-02-03 GB20050002250en_HK
patents.description.ccCNen_HK
patents.identifier.publicationCN 101180066en_HK
patents.relation.familyAU 2006210715 (A1) 2006-08-10en_HK
patents.relation.familyCA 2596959 (A1) 2006-08-10en_HK
patents.relation.familyCN 101180066 (A) 2008-05-14en_HK
patents.relation.familyEP 1846004 (A1) 2007-10-24en_HK
patents.relation.familyJP 2008528665 (A) 2008-07-31en_HK
patents.relation.familyUS 2008319184 (A1) 2008-12-25en_HK
patents.relation.familyWO 2006082397 (A1) 2006-08-10en_HK
patents.description.kindAen_HK
patents.typePatent_publisheden_HK

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