published patent: METHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS

TitleMETHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS
Priority Date2002-08-30 PCT/GB2002003941
2001-08-31 US 09/944951
Inventors
Issue Date2004
Citation
EP Published Patent application EP 1421211. European Patent Office (EPO), Escapenet, 2004 How to Cite?
AbstractIn a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA or an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from amother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient.; In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.
Persistent Identifierhttp://hdl.handle.net/10722/176733
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:25Z-
dc.date.available2012-11-30T08:38:25Z-
dc.date.issued2004-
dc.identifier.citationEP Published Patent application EP 1421211. European Patent Office (EPO), Escapenet, 2004en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176733-
dc.description.abstractIn a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA or an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from amother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient.; In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleMETHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALSen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorLo, Yuk Ming Dennisen_HK
dc.contributor.inventorPoon, LLMen_HK
patents.identifier.applicationEP 20020758554en_HK
patents.description.assigneeUNIV HONG KONG CHINESE [CN]en_HK
patents.description.countryEuropean Patent Officeen_HK
patents.date.publication2004-05-26en_HK
dc.relation.referencesXP 002247508en_HK
dc.relation.referencesXP 002247509en_HK
dc.relation.referencesXP 002247510en_HK
dc.relation.referencesXP 002247511en_HK
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dc.relation.referencesXP 002910406en_HK
patents.date.application2002-08-30en_HK
patents.date.priority2002-08-30 PCT/GB2002003941en_HK
patents.date.priority2001-08-31 US 09/944951en_HK
patents.description.ccEPen_HK
patents.identifier.publicationEP 1421211en_HK
patents.relation.familyAT 353977 (T) 2007-03-15en_HK
patents.relation.familyAU 2002324135 (A1) 2003-03-18en_HK
patents.relation.familyCA 2456140 (A1) 2003-03-13en_HK
patents.relation.familyCN 1665936 (A) 2005-09-07en_HK
patents.relation.familyCN 100352939 (C) 2007-12-05en_HK
patents.relation.familyDE 60218182 (T2) 2008-02-07en_HK
patents.relation.familyDK 1421211 (T3) 2007-05-29en_HK
patents.relation.familyEP 1421211 (A2) 2004-05-26en_HK
patents.relation.familyES 2280562 (T3) 2007-09-16en_HK
patents.relation.familyHK 1076840 (A1) 2008-05-23en_HK
patents.relation.familyJP 2005501566 (A) 2005-01-20en_HK
patents.relation.familyPT 1421211 (E) 2007-03-30en_HK
patents.relation.familyUS 2003044388 (A1) 2003-03-06en_HK
patents.relation.familyUS 6927028 (B2) 2005-08-09en_HK
patents.relation.familyUS 2009170102 (A1) 2009-07-02en_HK
patents.relation.familyUS 8168382 (B2) 2012-05-01en_HK
patents.relation.familyUS 2005282185 (A1) 2005-12-22en_HK
patents.relation.familyUS 2012190029 (A1) 2012-07-26en_HK
patents.relation.familyWO 03020974 (A2) 2003-03-13en_HK
patents.description.kindA2en_HK
patents.typePatent_publisheden_HK

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