published patent: METHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS IN ONE SAMPLE

TitleMETHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS IN ONE SAMPLE
Priority Date2002-08-30 PCT/GB2002003941
2001-08-31 US 09/944951
Inventors
Issue Date2003
Citation
Canada Published Patent Application CA 2456140. Gatineau, Quebec: Canadian Intellectual Property Office (CIPO), 2003 How to Cite?
AbstractIn a first aspect, the present invention features methods for differentiatin g DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA or an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in D NA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from amother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the presen t invention features kits for differentiating DNA species originating from different individuals in a biological sample.
Persistent Identifierhttp://hdl.handle.net/10722/176576

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:08Z-
dc.date.available2012-11-30T08:38:08Z-
dc.date.issued2003-
dc.identifier.citationCanada Published Patent Application CA 2456140. Gatineau, Quebec: Canadian Intellectual Property Office (CIPO), 2003en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176576-
dc.description.abstractIn a first aspect, the present invention features methods for differentiatin g DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA or an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in D NA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from amother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the presen t invention features kits for differentiating DNA species originating from different individuals in a biological sample.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleMETHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS IN ONE SAMPLEen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorLo, Yuk Ming Dennisen_HK
dc.contributor.inventorPoon, LLMen_HK
patents.identifier.applicationCA 20022456140en_HK
patents.description.assigneeUNIV HONG KONG CHINESE [CN]en_HK
patents.description.countryCanadaen_HK
patents.date.publication2003-03-13en_HK
patents.date.application2002-08-30en_HK
patents.date.priority2002-08-30 PCT/GB2002003941en_HK
patents.date.priority2001-08-31 US 09/944951en_HK
patents.description.ccCAen_HK
patents.identifier.publicationCA 2456140en_HK
patents.relation.familyAT 353977 (T) 2007-03-15en_HK
patents.relation.familyAU 2002324135 (A1) 2003-03-18en_HK
patents.relation.familyCA 2456140 (A1) 2003-03-13en_HK
patents.relation.familyCN 1665936 (A) 2005-09-07en_HK
patents.relation.familyCN 100352939 (C) 2007-12-05en_HK
patents.relation.familyDE 60218182 (T2) 2008-02-07en_HK
patents.relation.familyDK 1421211 (T3) 2007-05-29en_HK
patents.relation.familyEP 1421211 (A2) 2004-05-26en_HK
patents.relation.familyES 2280562 (T3) 2007-09-16en_HK
patents.relation.familyHK 1076840 (A1) 2008-05-23en_HK
patents.relation.familyJP 2005501566 (A) 2005-01-20en_HK
patents.relation.familyPT 1421211 (E) 2007-03-30en_HK
patents.relation.familyUS 2003044388 (A1) 2003-03-06en_HK
patents.relation.familyUS 6927028 (B2) 2005-08-09en_HK
patents.relation.familyUS 2009170102 (A1) 2009-07-02en_HK
patents.relation.familyUS 8168382 (B2) 2012-05-01en_HK
patents.relation.familyUS 2005282185 (A1) 2005-12-22en_HK
patents.relation.familyUS 2012190029 (A1) 2012-07-26en_HK
patents.relation.familyWO 03020974 (A2) 2003-03-13en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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