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  Patent History
  • Application
    AU 20020022943D 2001-07-12
  • Publication
    AU 2294302 2002-01-30
Supplementary

published patent: Enzyme activated chemotherapy of liver cancer

TitleEnzyme activated chemotherapy of liver cancer
Priority Date2000-07-14 US 09/218942P
2001-07-12 PCT/US2001021975
Inventors
Issue Date2002
Citation
Australia Published Patent Application AU 2294302. Australia: IP Australia, 2002 How to Cite?
AbstractThe present invention provides methods of screening for anti-cancer drugs based on the activities of overexpressed enzymes by the cancer cells to convert non-toxic compounds to cytotoxic drugs which can specifically kill these cancer cells. In particular, the present invention provides methods of screening for anti-cancer drugs which can be used to treat liver cancer, especially hepatocellular cercinoma. The present invention also provides methods of treating cancers, in particular liver cancer, especially hepatocellular carcinoma, by administering to a subject the drugs selected by the screning methods of the present invention. In a particular embodiment, naphthalene or a derivative thereof is administered to a subject. The present invention further provides pharmaceutical compositions for treating or ameliorating cancers as well as kits containing such compositions.
Persistent Identifierhttp://hdl.handle.net/10722/176551

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:07Z-
dc.date.available2012-11-30T08:38:07Z-
dc.date.issued2002-
dc.identifier.citationAustralia Published Patent Application AU 2294302. Australia: IP Australia, 2002en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176551-
dc.description.abstractThe present invention provides methods of screening for anti-cancer drugs based on the activities of overexpressed enzymes by the cancer cells to convert non-toxic compounds to cytotoxic drugs which can specifically kill these cancer cells. In particular, the present invention provides methods of screening for anti-cancer drugs which can be used to treat liver cancer, especially hepatocellular cercinoma. The present invention also provides methods of treating cancers, in particular liver cancer, especially hepatocellular carcinoma, by administering to a subject the drugs selected by the screning methods of the present invention. In a particular embodiment, naphthalene or a derivative thereof is administered to a subject. The present invention further provides pharmaceutical compositions for treating or ameliorating cancers as well as kits containing such compositions.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleEnzyme activated chemotherapy of liver canceren_HK
dc.typePatenten_US
dc.contributor.inventorStephen Sum Man Chungen_HK
patents.identifier.applicationAU 20020022943Den_HK
patents.description.assigneeUNIV HONG KONGen_HK
patents.description.countryAustraliaen_HK
patents.date.publication2002-01-30en_HK
patents.date.application2001-07-12en_HK
patents.date.priority2000-07-14 US 09/218942Pen_HK
patents.date.priority2001-07-12 PCT/US2001021975en_HK
patents.description.ccAUen_HK
patents.identifier.publicationAU 2294302en_HK
patents.relation.familyAU 2294302 (A) 2002-01-30en_HK
patents.relation.familyCN 1458978 (A) 2003-11-26en_HK
patents.relation.familyUS 2003212147 (A1) 2003-11-13en_HK
patents.relation.familyWO 0206514 (A1) 2002-01-24en_HK
patents.description.kindAen_HK
patents.typePatent_publisheden_HK

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