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  Patent History
  • Application
    CN 20018015671 2001-07-12
  • Publication
    CN 1458978 2003-11-26
Supplementary

published patent: Enzyme activated chemotherapy of liver cancer

TitleEnzyme activated chemotherapy of liver cancer
Priority Date2000-07-14 US 09/218942P
Inventors
Issue Date2003
Citation
China Published Patent Application CN 1458978. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2003 How to Cite?
AbstractThe present invention provides methods of screening for anti-cancer drugs based on the activities of overexpressed enzymes by the cancer cells to convert non-toxic compounds to cytotoxic drugs which can specifically kill these cancer cells. In particular, the present invention provides methods of screening for anti-cancer drugs which can be used to treat liver cancer, especially hepatocellular cercinoma. The present invention also provides methods of treating cancers, in particular liver cancer, especially hepatocellular carcinoma, by administering to a subject the drugs selected by the screning methods of the present invention. In a particular embodiment, naphthalene or a derivative thereof is administered to a subject. The present invention further provides pharmaceutical compositions for treating or ameliorating cancers as well as kits containing such compositions.
Persistent Identifierhttp://hdl.handle.net/10722/176667

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:19Z-
dc.date.available2012-11-30T08:38:19Z-
dc.date.issued2003-
dc.identifier.citationChina Published Patent Application CN 1458978. Beijing, PRC: State Intellectual Property Office (SIPO) of the P.R.C., 2003en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176667-
dc.description.abstractThe present invention provides methods of screening for anti-cancer drugs based on the activities of overexpressed enzymes by the cancer cells to convert non-toxic compounds to cytotoxic drugs which can specifically kill these cancer cells. In particular, the present invention provides methods of screening for anti-cancer drugs which can be used to treat liver cancer, especially hepatocellular cercinoma. The present invention also provides methods of treating cancers, in particular liver cancer, especially hepatocellular carcinoma, by administering to a subject the drugs selected by the screning methods of the present invention. In a particular embodiment, naphthalene or a derivative thereof is administered to a subject. The present invention further provides pharmaceutical compositions for treating or ameliorating cancers as well as kits containing such compositions.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleEnzyme activated chemotherapy of liver canceren_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorChung Stephen Sum Manen_HK
patents.identifier.applicationCN 20018015671en_HK
patents.description.assigneeUNIV OF HONG KONG [HK]en_HK
patents.description.countryChina, PRCen_HK
patents.date.publication2003-11-26en_HK
patents.date.application2001-07-12en_HK
patents.date.priority2000-07-14 US 09/218942Pen_HK
patents.description.ccCNen_HK
patents.identifier.publicationCN 1458978en_HK
patents.relation.familyAU 2294302 (A) 2002-01-30en_HK
patents.relation.familyCN 1458978 (A) 2003-11-26en_HK
patents.relation.familyUS 2003212147 (A1) 2003-11-13en_HK
patents.relation.familyWO 0206514 (A1) 2002-01-24en_HK
patents.description.kindAen_HK
patents.typePatent_publisheden_HK

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