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  Patent History
  • Application
    PC T/US2001021975 2001-07-12
  • Publication
    WO 0206514 2002-01-24
Supplementary

published patent: ENZYME ACTIVATED CHEMOTHERAPY OF LIVER CANCER

TitleENZYME ACTIVATED CHEMOTHERAPY OF LIVER CANCER
Priority Date2000-07-14 US 09/218942P
Inventors
Issue Date2002
Citation
WO Published patent application WO 0206514. World Intellectual Property Organization (WIPO), PatentScope, 2002 How to Cite?
AbstractThe present invention provides methods of screening for anti-cancer drugs based on the activities of overexpressed enzymes by the cancer cells to convert non-toxic compounds to cytotoxic drugs which can specifically kill these cancer cells. In particular, the present invention provides methods of screening for anti-cancer drugs which can be used to treat liver cancer, especially hepatocellular cercinoma. The present invention also provides methods of treating cancers, in particular liver cancer, especially hepatocellular carcinoma, by administering to a subject the drugs selected by the screning methods of the present invention. In a particular embodiment, naphthalene or a derivative thereof is administered to a subject. The present invention further provides pharmaceutical compositions for treating or ameliorating cancers as well as kits containing such compositions.
Persistent Identifierhttp://hdl.handle.net/10722/177053

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:39:00Z-
dc.date.available2012-11-30T08:39:00Z-
dc.date.issued2002-
dc.identifier.citationWO Published patent application WO 0206514. World Intellectual Property Organization (WIPO), PatentScope, 2002en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177053-
dc.description.abstractThe present invention provides methods of screening for anti-cancer drugs based on the activities of overexpressed enzymes by the cancer cells to convert non-toxic compounds to cytotoxic drugs which can specifically kill these cancer cells. In particular, the present invention provides methods of screening for anti-cancer drugs which can be used to treat liver cancer, especially hepatocellular cercinoma. The present invention also provides methods of treating cancers, in particular liver cancer, especially hepatocellular carcinoma, by administering to a subject the drugs selected by the screning methods of the present invention. In a particular embodiment, naphthalene or a derivative thereof is administered to a subject. The present invention further provides pharmaceutical compositions for treating or ameliorating cancers as well as kits containing such compositions.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleENZYME ACTIVATED CHEMOTHERAPY OF LIVER CANCERen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorChung, Stephen, Sum, Manen_HK
patents.identifier.applicationPC T/US2001021975en_HK
patents.description.assigneeUNIV HONG KONG [CN]; CHUNG STEPHEN SUM MAN [CN]en_HK
patents.description.countryWorld Intellectual Property Organization (WIPO)en_HK
patents.date.publication2002-01-24en_HK
patents.date.application2001-07-12en_HK
patents.date.priority2000-07-14 US 09/218942Pen_HK
patents.description.ccWOen_HK
patents.identifier.publicationWO 0206514en_HK
patents.relation.familyAU 2294302 (A) 2002-01-30en_HK
patents.relation.familyCN 1458978 (A) 2003-11-26en_HK
patents.relation.familyUS 2003212147 (A1) 2003-11-13en_HK
patents.relation.familyWO 0206514 (A1) 2002-01-24en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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