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  Patent History
  • Application
    US 12/706483 2010-02-16
  • Publication
    US 20110046747 2011-02-24

published patent: Antibacterial Surface And Method Of Fabrication

TitleAntibacterial Surface And Method Of Fabrication
Priority Date2010-02-16 US 12/706483
2009-02-19 US 12/153840P
2009-02-20 US 12/154278P
Inventors
Issue Date2011
Citation
US Published patent application 20110046747. Washington, DC: US Patent and Trademark Office (USPTO), 2011 How to Cite?
AbstractThis Invention Involves A Plasma Treated And Controllable Release Antimicrobial Peptide Coated Titanium Alloy For Surgical Implantation, Where The Alloy With Antimicrobial Properties Is Fabricated Using Surface Techniques Without Adversely Compromising Its Biocompatibility And Original Mechanical Properties. The Surface Techniques Form Antimicrobial Layers On The Alloy Capable Of Resisting Microbial Adhesion And Proliferation, While Allowing Mammalian Cell Adhesion And Proliferation When The Alloy Is Implanted To Human Body. In One Embodiment, Piii&D Is Applied To Incorporate Ions, Electrons, Free Radicals, Atoms Or Molecules On A Titanium Alloy Substrate. A Pressurized Hydrothermal Treatment Can Be Carried Out To Establish Reactive Functional Groups For Antimicrobial Purpose Or For Connecting The Substrate And External Antimicrobial Molecules. An Outermost Layer Of The Titanium Alloy Includes Antibacterial Peptides Possessing A Controllable Release Mechanism, And Is Fabricated Alone Or In An Assembly Of The Aforementioned Basal Surface Layers. The Controllable Release Mechanism Is Able To Withstand Long-Term Deep Tissue Infection After Surgery, And In An Embodiment Comprises Aptes As A Linker Molecule.
Persistent Identifierhttp://hdl.handle.net/10722/126684
References

 

DC FieldValueLanguage
dc.date.accessioned2010-10-31T12:42:29Z-
dc.date.available2010-10-31T12:42:29Z-
dc.date.issued2011-
dc.identifier.citationUS Published patent application 20110046747. Washington, DC: US Patent and Trademark Office (USPTO), 2011en_HK
dc.identifier.urihttp://hdl.handle.net/10722/126684-
dc.description.abstractThis Invention Involves A Plasma Treated And Controllable Release Antimicrobial Peptide Coated Titanium Alloy For Surgical Implantation, Where The Alloy With Antimicrobial Properties Is Fabricated Using Surface Techniques Without Adversely Compromising Its Biocompatibility And Original Mechanical Properties. The Surface Techniques Form Antimicrobial Layers On The Alloy Capable Of Resisting Microbial Adhesion And Proliferation, While Allowing Mammalian Cell Adhesion And Proliferation When The Alloy Is Implanted To Human Body. In One Embodiment, Piii&D Is Applied To Incorporate Ions, Electrons, Free Radicals, Atoms Or Molecules On A Titanium Alloy Substrate. A Pressurized Hydrothermal Treatment Can Be Carried Out To Establish Reactive Functional Groups For Antimicrobial Purpose Or For Connecting The Substrate And External Antimicrobial Molecules. An Outermost Layer Of The Titanium Alloy Includes Antibacterial Peptides Possessing A Controllable Release Mechanism, And Is Fabricated Alone Or In An Assembly Of The Aforementioned Basal Surface Layers. The Controllable Release Mechanism Is Able To Withstand Long-Term Deep Tissue Infection After Surgery, And In An Embodiment Comprises Aptes As A Linker Molecule.en_HK
dc.languageengen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleAntibacterial Surface And Method Of Fabricationen_HK
dc.typePatenten_HK
dc.identifier.emailYeung, KWK: wkkyeung@hkucc.hku.hken_HK
dc.identifier.emailCheung, KMC: cheungmc@hku.hken_HK
dc.identifier.emailLuk, KDK: hrmoldk@hkucc.hku.hken_HK
dc.identifier.emailYeung, CY: sheepyyan@gmail.comen_HK
dc.identifier.emailKao, RYT: rytkao@hkucc.hku.hken_HK
dc.identifier.authorityYeung, KWK=rp00309en_HK
dc.identifier.authorityCheung, KMC=rp00387en_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.identifier.authorityKao, RYT=rp00481en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros180225en_HK
dc.identifier.hkuros166291-
dc.contributor.inventorYeung, KWKen_HK
dc.contributor.inventorCheung, KMCen_HK
dc.contributor.inventorLuk, KDKen_HK
dc.contributor.inventorYeung, CYen_HK
dc.contributor.inventorKao, RYTen_HK
dc.contributor.inventorChu, PKen_HK
patents.identifier.applicationUS 12/706483en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2011-02-24en_HK
dc.relation.referencesUS 5782908 (A) 1998-07-21en_HK
dc.relation.referencesUS 6183255 (B1) 2001-02-06en_HK
dc.relation.referencesWO 2008068531 (A2) 2008-06-12en_HK
dc.relation.referencesWO 2008068531 (A3) 2009-04-09en_HK
patents.identifier.hkutechidO&T-2009-00305-1-
patents.date.application2010-02-16en_HK
patents.date.priority2010-02-16 US 12/706483en_HK
patents.date.priority2009-02-19 US 12/153840Pen_HK
patents.date.priority2009-02-20 US 12/154278Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20110046747en_HK
patents.relation.familyCN 102341132 (A) 2012-02-01en_HK
patents.relation.familyEP 2398517 (A2) 2011-12-28en_HK
patents.relation.familyUS 2011046747 (A1) 2011-02-24en_HK
patents.relation.familyWO 2010094212 (A2) 2010-08-26en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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