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  Patent History
  • Application
    EP 20100743393 2010-02-18
  • Publication
    EP 2398517 2011-12-28
Supplementary

published patent: ANTIBACTERIAL SURFACE AND METHOD OF FABRICATION

TitleANTIBACTERIAL SURFACE AND METHOD OF FABRICATION
Priority Date2010-02-18 PCT/CN2010000216
2009-02-19 US 12/153840P
2009-02-20 US 12/154278P
Inventors
Issue Date2011
Citation
EP Published Patent application EP 2398517. European Patent Office (EPO), Escapenet, 2011 How to Cite?
AbstractThis invention involves a plasma treated and controllable release antimicrobial peptide coated titanium alloy for surgical implantation, where the alloy with antimicrobial properties is fabricated using surface techniques without adversely compromising its biocompatibility and original mechanical properties. The surface techniques form antimicrobial layers on the alloy capable of resisting microbial adhesion and proliferation, while allowing mammalian cell adhesion and proliferation when the alloy is implanted to human body. In one embodiment, PIII&D is applied to incorporate ions, electrons, free radicals, atoms or molecules on a titanium alloy substrate. A pressurized hydrothermal treatment can be carried out to establish reactive functional groups for antimicrobial purpose or for connecting the substrate and external antimicrobial molecules.; An outermost layer of the titanium alloy includes antibacterial peptides possessing a controllable release mechanism, and is fabricated alone or in an assembly of the aforementioned basal surface layers. The controllable release mechanism is able to withstand long-term deep tissue infection after surgery, and in an embodiment comprises APTES as a linker molecule.
Persistent Identifierhttp://hdl.handle.net/10722/176767

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:27Z-
dc.date.available2012-11-30T08:38:27Z-
dc.date.issued2011-
dc.identifier.citationEP Published Patent application EP 2398517. European Patent Office (EPO), Escapenet, 2011en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176767-
dc.description.abstractThis invention involves a plasma treated and controllable release antimicrobial peptide coated titanium alloy for surgical implantation, where the alloy with antimicrobial properties is fabricated using surface techniques without adversely compromising its biocompatibility and original mechanical properties. The surface techniques form antimicrobial layers on the alloy capable of resisting microbial adhesion and proliferation, while allowing mammalian cell adhesion and proliferation when the alloy is implanted to human body. In one embodiment, PIII&D is applied to incorporate ions, electrons, free radicals, atoms or molecules on a titanium alloy substrate. A pressurized hydrothermal treatment can be carried out to establish reactive functional groups for antimicrobial purpose or for connecting the substrate and external antimicrobial molecules.; An outermost layer of the titanium alloy includes antibacterial peptides possessing a controllable release mechanism, and is fabricated alone or in an assembly of the aforementioned basal surface layers. The controllable release mechanism is able to withstand long-term deep tissue infection after surgery, and in an embodiment comprises APTES as a linker molecule.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleANTIBACTERIAL SURFACE AND METHOD OF FABRICATIONen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorYeung, KWKen_HK
dc.contributor.inventorCheung, KMCen_HK
dc.contributor.inventorLuk, Dipkei Keithen_HK
dc.contributor.inventorYeung, Cheyanen_HK
dc.contributor.inventorKao, Yitsun Richarden_HK
dc.contributor.inventorChu, Kimho Paulen_HK
patents.identifier.applicationEP 20100743393en_HK
patents.description.assigneeVERSITECH LTD [CN]; UNIV CITY HONG KONG [CN]en_HK
patents.description.countryEuropean Patent Officeen_HK
patents.date.publication2011-12-28en_HK
patents.identifier.hkutechidO&T-2009-00305-3-
patents.identifier.hkutechidO&T-2009-00305-4-
patents.identifier.hkutechidO&T-2009-00305-5-
patents.identifier.hkutechidO&T-2009-00305-7-
patents.date.application2010-02-18en_HK
patents.date.priority2010-02-18 PCT/CN2010000216en_HK
patents.date.priority2009-02-19 US 12/153840Pen_HK
patents.date.priority2009-02-20 US 12/154278Pen_HK
patents.description.ccEPen_HK
patents.identifier.publicationEP 2398517en_HK
patents.relation.familyCN 102341132 (A) 2012-02-01en_HK
patents.relation.familyEP 2398517 (A2) 2011-12-28en_HK
patents.relation.familyUS 2011046747 (A1) 2011-02-24en_HK
patents.relation.familyWO 2010094212 (A2) 2010-08-26en_HK
patents.description.kindA2en_HK
patents.typePatent_publisheden_HK

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