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- Publisher Website: 10.1034/j.1600-0412.1999.780715.x
- Scopus: eid_2-s2.0-0033054666
- PMID: 10422914
- WOS: WOS:000081495200015
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Article: Wide local excision (WLE) for vaginal intraepithelial neoplasia (VAIN)
Title | Wide local excision (WLE) for vaginal intraepithelial neoplasia (VAIN) |
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Authors | |
Keywords | Excision Occult cancer Treatment of VAIN |
Issue Date | 1999 |
Publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-0412 |
Citation | Acta Obstetricia Et Gynecologica Scandinavica, 1999, v. 78 n. 7, p. 648-652 How to Cite? |
Abstract | Background. To assess the use of wide local excision in the treatment of VAIN. Methods. A retrospective review on 40 WLE procedures for VAIN. Results. The mean age was 60 years. Thirty-six (90%) patients had previous treatment for genital tract cancer or pre-cancer. The median duration and blood loss during operation was 45 minutes and 50 mls respectively. Fifteen complications affected 11 patients. Only one of five patients with 'vaginal cancer' was diagnosed prior to WLE. Of the 35 patients treated for VAIN 3, 12 (34%) developed abnormal cytology during follow up - three had residual VAIN 3, five had recurrent VAIN 3 and four had invasive cancer diagnosed. The remaining 23 (66%) patients were disease free at a median follow up of 44 months. Conclusions. Ablative therapy for VAIN 3 is unsafe as occult invasive foci can be missed by biopsy. WLE is efficacious in treating high grade VAIN 3. Long term surveillance of the lower genital tract is needed to diagnose metachronous lesions. |
Persistent Identifier | http://hdl.handle.net/10722/87244 |
ISSN | 2023 Impact Factor: 3.5 2023 SCImago Journal Rankings: 1.384 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Cheng, D | en_HK |
dc.contributor.author | Ng, TY | en_HK |
dc.contributor.author | Ngan, HYS | en_HK |
dc.contributor.author | Wong, LC | en_HK |
dc.date.accessioned | 2010-09-06T09:27:11Z | - |
dc.date.available | 2010-09-06T09:27:11Z | - |
dc.date.issued | 1999 | en_HK |
dc.identifier.citation | Acta Obstetricia Et Gynecologica Scandinavica, 1999, v. 78 n. 7, p. 648-652 | en_HK |
dc.identifier.issn | 0001-6349 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/87244 | - |
dc.description.abstract | Background. To assess the use of wide local excision in the treatment of VAIN. Methods. A retrospective review on 40 WLE procedures for VAIN. Results. The mean age was 60 years. Thirty-six (90%) patients had previous treatment for genital tract cancer or pre-cancer. The median duration and blood loss during operation was 45 minutes and 50 mls respectively. Fifteen complications affected 11 patients. Only one of five patients with 'vaginal cancer' was diagnosed prior to WLE. Of the 35 patients treated for VAIN 3, 12 (34%) developed abnormal cytology during follow up - three had residual VAIN 3, five had recurrent VAIN 3 and four had invasive cancer diagnosed. The remaining 23 (66%) patients were disease free at a median follow up of 44 months. Conclusions. Ablative therapy for VAIN 3 is unsafe as occult invasive foci can be missed by biopsy. WLE is efficacious in treating high grade VAIN 3. Long term surveillance of the lower genital tract is needed to diagnose metachronous lesions. | en_HK |
dc.language | eng | en_HK |
dc.publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-0412 | en_HK |
dc.relation.ispartof | Acta Obstetricia et Gynecologica Scandinavica | en_HK |
dc.subject | Excision | en_HK |
dc.subject | Occult cancer | en_HK |
dc.subject | Treatment of VAIN | en_HK |
dc.title | Wide local excision (WLE) for vaginal intraepithelial neoplasia (VAIN) | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1936-0851&volume=78&spage=648&epage=652&date=1999&atitle=Wide+local+excision+(WLE)+for+vaginal+intraepithelial+neoplasia+(VAIN) | en_HK |
dc.identifier.email | Ngan, HYS:hysngan@hkucc.hku.hk | en_HK |
dc.identifier.authority | Ngan, HYS=rp00346 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1034/j.1600-0412.1999.780715.x | - |
dc.identifier.pmid | 10422914 | - |
dc.identifier.scopus | eid_2-s2.0-0033054666 | en_HK |
dc.identifier.hkuros | 47609 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0033054666&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 78 | en_HK |
dc.identifier.issue | 7 | en_HK |
dc.identifier.spage | 648 | en_HK |
dc.identifier.epage | 652 | en_HK |
dc.identifier.isi | WOS:000081495200015 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Cheng, D=7402806161 | en_HK |
dc.identifier.scopusauthorid | Ng, TY=7402229853 | en_HK |
dc.identifier.scopusauthorid | Ngan, HYS=34571944100 | en_HK |
dc.identifier.scopusauthorid | Wong, LC=7402092003 | en_HK |
dc.identifier.issnl | 0001-6349 | - |