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  Patent History
  • Application
    US 09/011200 2001-11-09
  • Publication
    US 20030180829 2003-09-25
  • Granted
    US 6632631 2003-10-14
  Patent Family
Supplementary

granted patent: Methods For The Identification Of Inhibitors Of Homocitrate Synthase As Antibiotics

TitleMethods For The Identification Of Inhibitors Of Homocitrate Synthase As Antibiotics
Granted PatentUS 6632631
Granted Date2003-10-14
Priority Date2001-11-09 US 09/011200
Inventors
Shuster, JTanzer, THamer, LAdachi, KDeZwaan, TLo, CSCMontenegro-Chamorro, MVFrank, SDarveaux, BMahanty, SHeiniger, RSkalchunes, APan, HTarpey, R
Issue Date2003
Citation
US Patent 6632631. Washington, DC: US Patent and Trademark Office (USPTO), 2003 How to Cite?
AbstractThe Present Inventors Have Discovered That Homocitrate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Homocitrate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Homocitrate Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Homocitrate Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.
Persistent Identifierhttp://hdl.handle.net/10722/45688
References

 

DC FieldValueLanguage
dc.date.accessioned2007-10-30T06:32:42Z-
dc.date.available2007-10-30T06:32:42Z-
dc.date.issued2003-
dc.identifier.citationUS Patent 6632631. Washington, DC: US Patent and Trademark Office (USPTO), 2003en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45688-
dc.description.abstractThe Present Inventors Have Discovered That Homocitrate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Homocitrate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Homocitrate Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Homocitrate Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.</Ptext>en_HK
dc.format.extent3078397 bytes-
dc.format.extent2788 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.titleMethods For The Identification Of Inhibitors Of Homocitrate Synthase As Antibioticsen_HK
dc.typePatenten_HK
dc.description.naturepublished_or_final_version-
dc.contributor.inventorShuster, Jen_HK
dc.contributor.inventorTanzer, Ten_HK
dc.contributor.inventorHamer, Len_HK
dc.contributor.inventorAdachi, Ken_HK
dc.contributor.inventorDeZwaan, Ten_HK
dc.contributor.inventorLo, CSCen_HK
dc.contributor.inventorMontenegro-Chamorro, MVen_HK
dc.contributor.inventorFrank, Sen_HK
dc.contributor.inventorDarveaux, Ben_HK
dc.contributor.inventorMahanty, Sen_HK
dc.contributor.inventorHeiniger, Ren_HK
dc.contributor.inventorSkalchunes, Aen_HK
dc.contributor.inventorPan, Hen_HK
dc.contributor.inventorTarpey, Ren_HK
patents.identifier.applicationUS 09/011200en_HK
patents.identifier.grantedUS 6632631en_HK
patents.description.assigneeParadigm Genetics Inc [Us]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2003-09-25en_HK
patents.date.granted2003-10-14en_HK
dc.relation.referencesUS 4920109 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920111 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920112 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920113 (A) 1990-04-24en_HK
dc.relation.referencesUS 4921844 (A) 1990-05-01en_HK
dc.relation.referencesUS 5976848 (A) 1999-11-02en_HK
dc.relation.referencesUS 6074830 (A) 2000-06-13en_HK
patents.date.application2001-11-09en_HK
patents.date.priority2001-11-09 US 09/011200en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20030180829en_HK
patents.relation.familyAU 2002365038 (A8) 2003-06-10en_HK
patents.relation.familyCA 2469772 (A1) 2003-06-05en_HK
patents.relation.familyEP 1481080 (A2) 2004-12-01en_HK
patents.relation.familyJP 2005510230 (A) 2005-04-21en_HK
patents.relation.familyUS 2003180829 (A1) 2003-09-25en_HK
patents.relation.familyUS 6632631 (B1) 2003-10-14en_HK
patents.relation.familyUS 2003104511 (A1) 2003-06-05en_HK
patents.relation.familyUS 6723529 (B2) 2004-04-20en_HK
patents.relation.familyWO 03046130 (A2) 2003-06-05en_HK
patents.description.kindB1en_HK
patents.typePatent_granteden_HK

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