Progressive resistance exercise improves glycemic control in people with type 2 diabetes mellitus: a meta-analysis

Abstract

<p>Objective To evaluate the safety and effectiveness of progressive resistance exercise on glycemic control in people with type 2 diabetes. Methods Research papers involving progressive resistance exercise for people with type 2diabetes mellitus weresearched in the Cochrane Library (The first issue in 2012), MEDLINE, EMBASE, PUBMED, OVID, CNKI, CBMdisc and ChinaInfo, and these papers were limited to randomized controlled trials(RCT). Papers were selected according to the inclusion and exclusion criteria by 2reviewers, and quality of the enrolled papers was evaluated based on the Cochrane Handbook. Meta-analysis was conducted by using RevMan5.1, or descriptive analysis was performed. Results The search yielded nine relevant trials that evaluated 518people with type 2diabetes. Compared to no exercise, progressive resistance exercise led to statistically significant reductions in HbA1c (SMD=-1.19,95%CI=-1.39to-0.99,P<0.01). When compared to aerobic exercise there was no significant difference in HbA1c(P>0.05). Progressive resistance exercise resulted in greater improvements in muscle strength than aerobic exercise (SMD=-1.02,95%CI=-1.49to-0.55,P<0.01) or no exercise (SMD=-1.23,95%CI=-1.51to-0.95,P<0.01). There was no significant change in body composition(P>0.05). Conclusion Progressive resistance exercise effectively decreases HbA1c and increases muscle strength in patients with type 2diabetes mellitus. Progressive resistance exercise isa feasible option in the management of glycaemia for this population.</p>

目的 评价渐进性抗阻力运动对2型糖尿病患者血糖控制的有效性和安全性.方法 计算机检索Cochrane Library(2012年第1期)、MEDLINE、EMBASE、PUBMED、OVID、中国知网(CNKI)、中国生物医学文献数据库(CBMdisc)及万方数据资源系统中关于2型糖尿病患者进行抗阻力运动的随机对照试验(RCT)(自数据库开始收录时间起至2013年6月),同时筛检纳入研究的参考文献进行Meta分析.结果 共纳入9项相关研究、共518例患者.与不运动组相比,渐进性抗阻力运动组的HbA1c水平显著降低(P＜0.01).与有氧运动组相比,两组HbA1c水平差异没有统计学意义(P＞0.05).渐进性抗阻力运动组的肌力改善水平明显高于有氧运动组和不运动组(均P＜0.01).三组身体成分差异无统计学意义(P＞0.05).结论 渐进性抗阻力运动对2型糖尿病患者降低糖化血红蛋白、改善肌力的效果显著,应加强抗阻力运动在2型糖尿病患者中的应用.