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Article: Microfluidic Chip‐Assisted Upconversion Luminescence Biosensing Platform for Point‐of‐Care Virus Diagnostics

TitleMicrofluidic Chip‐Assisted Upconversion Luminescence Biosensing Platform for Point‐of‐Care Virus Diagnostics
Authors
Keywordsmicrofluidic chip-assisted
point-of-care
upconversion luminescence
virus diagnostics
Issue Date15-Mar-2024
PublisherWiley
Citation
Advanced Healthcare Materials, 2024 How to Cite?
Abstract

Epidemics caused by multiple viruses continue to emerge, which have brought a terrible impact on human society. Identification of viral infections with high sensitivity and portability is of significant importance for the screening and management of diseases caused by viruses. Herein, a microfluidic chip (MFC)-assisted upconversion luminescence biosensing platform is designed and fabricated for point-of-care virus detection. Upconversion nanoparticles with excellent stability are successfully synthesized as luminescent agents for optical signal generation in the portable virus diagnostic platform. The relevant investigation results illustrate that the MFC-assisted virus diagnostic platform possesses outstanding performance such as good integration, high sensitivity (1.12 pg mL-1 ), ease of use, and portability. In addition, clinical sample test result verifies its more prominent virus diagnostic properties than commercially available rapid test strips. All of these thrilling capabilities imply that the designed portable virus diagnostic platform has great potential for future virus detection applications.


Persistent Identifierhttp://hdl.handle.net/10722/342108
ISSN
2023 Impact Factor: 10.0
2023 SCImago Journal Rankings: 2.337
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLiu, Yuan-
dc.contributor.authorLao, Xinyue-
dc.contributor.authorWong, Man‐Chung-
dc.contributor.authorSong, Menglin-
dc.contributor.authorLai, Huang-
dc.contributor.authorWang, Pui-
dc.contributor.authorMa, Yingjin-
dc.contributor.authorLi, Lihua-
dc.contributor.authorYang, Mo-
dc.contributor.authorChen, Honglin-
dc.contributor.authorHao, Jianhua-
dc.date.accessioned2024-04-02T08:25:38Z-
dc.date.available2024-04-02T08:25:38Z-
dc.date.issued2024-03-15-
dc.identifier.citationAdvanced Healthcare Materials, 2024-
dc.identifier.issn2192-2640-
dc.identifier.urihttp://hdl.handle.net/10722/342108-
dc.description.abstract<p>Epidemics caused by multiple viruses continue to emerge, which have brought a terrible impact on human society. Identification of viral infections with high sensitivity and portability is of significant importance for the screening and management of diseases caused by viruses. Herein, a microfluidic chip (MFC)-assisted upconversion luminescence biosensing platform is designed and fabricated for point-of-care virus detection. Upconversion nanoparticles with excellent stability are successfully synthesized as luminescent agents for optical signal generation in the portable virus diagnostic platform. The relevant investigation results illustrate that the MFC-assisted virus diagnostic platform possesses outstanding performance such as good integration, high sensitivity (1.12 pg mL<sup>-1</sup> ), ease of use, and portability. In addition, clinical sample test result verifies its more prominent virus diagnostic properties than commercially available rapid test strips. All of these thrilling capabilities imply that the designed portable virus diagnostic platform has great potential for future virus detection applications.<br></p>-
dc.languageeng-
dc.publisherWiley-
dc.relation.ispartofAdvanced Healthcare Materials-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectmicrofluidic chip-assisted-
dc.subjectpoint-of-care-
dc.subjectupconversion luminescence-
dc.subjectvirus diagnostics-
dc.titleMicrofluidic Chip‐Assisted Upconversion Luminescence Biosensing Platform for Point‐of‐Care Virus Diagnostics-
dc.typeArticle-
dc.identifier.doi10.1002/adhm.202303897-
dc.identifier.scopuseid_2-s2.0-85187655566-
dc.identifier.eissn2192-2659-
dc.identifier.isiWOS:001184301600001-
dc.identifier.issnl2192-2640-

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