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Book Chapter: Clonal Hematopoiesis and Its Functional Implications in MDS/AML
| Title | Clonal Hematopoiesis and Its Functional Implications in MDS/AML |
|---|---|
| Authors | |
| Issue Date | 28-Sep-2023 |
| Publisher | Springer Nature Singapore |
| Abstract | Clonal hematopoiesis (CH) is now a specifically recognized as a precursor myeloid neoplasm and comprised clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS). Various cohort studies have confirmed the association between CH and the subsequent development of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In addition, there is recent evidence to show that CH is associated with highlighted inflammatory responses and may influence non-hematological disease states in the general population and in patients with hematological malignancies. |
| Persistent Identifier | http://hdl.handle.net/10722/341849 |
| ISBN |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Singh, Gill Harinder Harry | - |
| dc.date.accessioned | 2024-03-26T05:37:40Z | - |
| dc.date.available | 2024-03-26T05:37:40Z | - |
| dc.date.issued | 2023-09-28 | - |
| dc.identifier.isbn | 9789819938094 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/341849 | - |
| dc.description.abstract | <p>Clonal hematopoiesis (CH) is now a specifically recognized as a precursor myeloid neoplasm and comprised clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS). Various cohort studies have confirmed the association between CH and the subsequent development of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In addition, there is recent evidence to show that CH is associated with highlighted inflammatory responses and may influence non-hematological disease states in the general population and in patients with hematological malignancies.<br></p> | - |
| dc.language | eng | - |
| dc.publisher | Springer Nature Singapore | - |
| dc.relation.ispartof | Pathogenesis and Treatment of Leukemia | - |
| dc.title | Clonal Hematopoiesis and Its Functional Implications in MDS/AML | - |
| dc.type | Book_Chapter | - |
| dc.identifier.doi | 10.1007/978-981-99-3810-0_28 | - |
| dc.identifier.eisbn | 9789819938100 | - |