Gill Harinder Harry Singh

 

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Professor Gill Harinder Harry Singh

Title:
Clinical Associate Professor

Contact Information
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Office:
QMH AB806 

Professor Gill Harinder Harry Singh

Title:
Clinical Associate Professor

Also Cited As:
Gill, H
Gill, HHS

Professional Qualifications
YearAwarding InstitutionQualification
2006The University of Hong KongMBBS
2009Royal College of PhysiciansMRCP (UK)
2009The University of Hong KongPDipID
2013Hong Kong College of PhyciciansFHKCP
2013The Hong Kong Academy of MedicineFHKAM (Medicine)
2018Royal College of Physicians of EdinburghFRCP (Edin)
2018Royal College of Physicians and Surgeons of GlasgowFRCP (Glasg)
2019Royal College of PathologistsFRCPath
2019The University of Hong KongMD
2020Royal College of PhysiciansFRCP (Lond)
2013Hong Kong College of PhysiciansFHKCP
2013Hong Kong College of PhysiciansFHKCP
2023Hong Kong College of PhysiciansFellow in Genetics and Genomics (Medicine)
Biography

Dr. Gill Harinder Singh Harry is currently Clinical Associate Professor at the Department of Medicine, School of Clinical Medicine, the University of Hong Kong. He graduated from the University of Hong Kong in 2006 and joined the Department of Medicine, Queen Mary Hospital in July 2007. He joined the University of Hong Kong as Clinical Assistant Professor in July 2014 and completed his training in Haematology and Haematological Oncology, and Advanced Internal Medicine in 2013 and 2014, respectively. He also underwent training in Haematopathology at the Department of Pathology, Queen Mary Hospital from 2017 to 2019 and was conferred Fellow of The Royal College of Pathologists in February 2019. He completed his doctorate degree in 2019 focusing on the genomics of myeloproliferative neoplasms. He was conferred First Fellow in Genetics and Genomics (Medicine) by the Hong Kong College of Physicians in 2023. He has published extensively in esteemed peer-reviewed journals, including Blood, Blood Advances, Haematologica, British Journal of Haematology, Bone Marrow Transplantation, Annals of Oncology, Journal of Clinical Oncology, Cancer and Science Translational Medicine. He is the service-lead for acute myeloid leukaemia (AML), myelodysplastic syndrome (MDS) and myeloproliferative neoplasm (MPN) in Queen Mary Hospital, Hong Kong.

One of his key research areas since 2010 is the application of oral arsenic trioxide in the treatment of acute promyelocytic leukaemia (APL) and other haematological malignancies. Important practice-changing observations were made. He showed that a second complete remission rate of 100% and 10-year overall survival of more than 80% can be achieved in relapsed APL with oral arsenic trioxide-based regimen without hematopoietic stem cell transplantation (HSCT). His work on frontline oral arsenic trioxide, all-trans-retinoic acid, ascorbic acid-based induction in newly diagnosed APL has also shown 100% complete remission rate with a 5-year leukaemia-free and overall survival of 100%, showing that a universal cure is achieved with the frontline oral arsenic trioxide-based regimen in APL. This is also the first study employing arsenic trioxide in its oral formulation worldwide. In another ongoing multicentre study, a completely chemotherapy-free and oral regimen for APL is being evaluated. He steered the research and development, and the clinical use of the Good Manufacturing Practice (GMP) grade oral arsenic trioxide (Arsenol ®), the first GMP grade oral formulation of arsenic trioxide worldwide.

Dr. Gill also leads research on MDS and MPN with specific focus on molecular alterations and novel therapeutics in these disorders. He is currently leading studies on the genomics of clonal haematopoiesis, MDS, secondary AML and MPN. He is also one of the key investigators of several global phase 2 and 3 studies evaluating the use of novel therapies in MDS and MPN.

He is one of the founding members and directors of the Asian Myeloid Working Group leading key regional studies on myeloid malignancies in Asia including the Asian MDS Genomics Registry, the APL Asian Consortium Study, and the Asian MPN Registry.

 
Honours, Awards & Prizes
AwardeesAward DateHonours / Awards / PrizesCategory
2013-12-01Best Original Research by Trainees 2013 (Bronze Medal): Hong Kong Academy of Medicine
Research Achievement
2013-10-01Young Investigator Research Grant 2013: Hong Kong College of Physicians
Research Achievement
2013-01-01Best Abstract in Clinical Medicine, 18th Medical Research Conference: Department of Medicine, the University of Hong Kong
Research Achievement
2014-05-01Best Abstract Award, Hong Kong Society of Haematology Annual Scientific Meeting 2013: Hong Kong Society of Haematology
Research Achievement
2013-06-01Training and Research Assistance Scheme 2013: Queen Mary Hospital Charitable Trust
Research Achievement
2014-05-01Best Abstract Award, Hong Kong Society of Haematology, Annual Scientific Meeting 2014: Hong Kong Society of Haematology
Research Achievement
2014-10-01Highest Score in Advanced Internal Medicine Exit Assessment: Hong Kong College of Physicians
Others
2023-10-21Sir David Todd Lectureship
Research Achievement
Ma, SKE
He, BA
Ip, HW
2017-09-01Faculty Outstanding Research Output Award: Li Ka Shing Faculty of Medicine, the University of Hong Kong
Research Achievement
Lie, AKW
Hwang, YYG
2013-12-01Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award): The University of Hong Kong
Teaching Accomplishment
2015-03-01Best Paper Award - the Hong Kong Society of Haematology Annual Scientific Meeting 2015: The Hong Kong Society of Haematology
Research Achievement
2017-01-01Best Abstract Award in Clinical Medicine: 22nd Medical Research Conference, Department of Medicine, HKU.
Research Achievement
2018-01-01Best Abstract in Clinical Medicine, Medical Research Conference 2018.: Department of Medicine, LKS Faculty of Medicine, the University of Hong Kong.
Research Achievement
Professional Societies
Term PeriodPositionProfessional Societies
07/2010 - presentMemberHong Kong Society of Haematology
07/2014 - presentMemberAmerican Society of Haematology
03/2021 - presentDirector and Founding MemberAsian Myeloid Working Group
07/2014 - presentMemberEuropean Haematology Association
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