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Book Chapter: Next-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML

TitleNext-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML
Authors
Issue Date28-Sep-2023
PublisherSpringer Nature Singapore
Abstract

Tyrosine kinases regulate a wide range of cellular pathways and are crucial to signal transduction. Their aberrant activities can contribute to leukaemogenesis via promoting proliferation, impeding differentiation, and inhibiting apoptosis. In this chapter, we discuss the role of FLT3 inhibition in acute myeloid leukemia (AML) and the use of FLT3 inhibitors in AML.


Persistent Identifierhttp://hdl.handle.net/10722/341835
ISBN

 

DC FieldValueLanguage
dc.contributor.authorSingh, Gill Harinder Harry-
dc.date.accessioned2024-03-26T05:37:34Z-
dc.date.available2024-03-26T05:37:34Z-
dc.date.issued2023-09-28-
dc.identifier.isbn9789819938094-
dc.identifier.urihttp://hdl.handle.net/10722/341835-
dc.description.abstract<p>Tyrosine kinases regulate a wide range of cellular pathways and are crucial to signal transduction. Their aberrant activities can contribute to leukaemogenesis via promoting proliferation, impeding differentiation, and inhibiting apoptosis. In this chapter, we discuss the role of FLT3 inhibition in acute myeloid leukemia (AML) and the use of FLT3 inhibitors in AML.<br></p>-
dc.languageeng-
dc.publisherSpringer Nature Singapore-
dc.relation.ispartofPathogenesis and Treatment of Leukemia-
dc.titleNext-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML-
dc.typeBook_Chapter-
dc.identifier.doi10.1007/978-981-99-3810-0_12-
dc.identifier.eisbn9789819938100-

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