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Conference Paper: Optogenetic fMRI interrogation of the olfactory system

TitleOptogenetic fMRI interrogation of the olfactory system
Authors
Ma, TWang, XWong, ECChong, PSSanchayyan, SLim, LWKhong, PLWu, EXLeong, TL
Issue Date2021
PublisherInternational Society of Magnetic Resonance Imaging (ISMRM) .
Citation
Proceedings of the 29th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Virtual Conference, Vancouver, BC, Canada, 15-20 May 2021, paper no. 2941 How to Cite?
AbstractThe olfactory system is one of the major sensory systems and has been often linked to numerous non-olfactory regions pivotal for sensory perception and higher-order cognition. However, the extent of where olfactory signals are distributed brain-wide remains poorly described. By optogenetically stimulating the excitatory projection neurons in olfactory bulb (OB), we interrogated the brain-wide functional organization of the olfactory system using fMRI. We revealed that OB neural activity propagated to regions that are associated with higher-order cognition, reward-related behaviors and multisensory processing.
DescriptionDigital Poster - Session D-168: fMRI of Animal Models - fMRI Using Animal Models: Applications - no. 2941
Persistent Identifierhttp://hdl.handle.net/10722/304198

 

DC FieldValueLanguage
dc.contributor.authorMa, T-
dc.contributor.authorWang, X-
dc.contributor.authorWong, EC-
dc.contributor.authorChong, PS-
dc.contributor.authorSanchayyan, S-
dc.contributor.authorLim, LW-
dc.contributor.authorKhong, PL-
dc.contributor.authorWu, EX-
dc.contributor.authorLeong, TL-
dc.date.accessioned2021-09-23T08:56:36Z-
dc.date.available2021-09-23T08:56:36Z-
dc.date.issued2021-
dc.identifier.citationProceedings of the 29th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Virtual Conference, Vancouver, BC, Canada, 15-20 May 2021, paper no. 2941-
dc.identifier.urihttp://hdl.handle.net/10722/304198-
dc.descriptionDigital Poster - Session D-168: fMRI of Animal Models - fMRI Using Animal Models: Applications - no. 2941-
dc.description.abstractThe olfactory system is one of the major sensory systems and has been often linked to numerous non-olfactory regions pivotal for sensory perception and higher-order cognition. However, the extent of where olfactory signals are distributed brain-wide remains poorly described. By optogenetically stimulating the excitatory projection neurons in olfactory bulb (OB), we interrogated the brain-wide functional organization of the olfactory system using fMRI. We revealed that OB neural activity propagated to regions that are associated with higher-order cognition, reward-related behaviors and multisensory processing.-
dc.languageeng-
dc.publisherInternational Society of Magnetic Resonance Imaging (ISMRM) .-
dc.relation.ispartofISMRM (International Society of Magnetic Resonance Imaging) Virtual Conference & Exhibition, 2021-
dc.titleOptogenetic fMRI interrogation of the olfactory system-
dc.typeConference_Paper-
dc.identifier.emailLim, LW: limlw@hku.hk-
dc.identifier.emailKhong, PL: plkhong@hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.emailLeong, TL: tlleong@hku.hk-
dc.identifier.authorityLim, LW=rp02088-
dc.identifier.authorityKhong, PL=rp00467-
dc.identifier.authorityWu, EX=rp00193-
dc.identifier.authorityLeong, TL=rp02483-
dc.identifier.hkuros325452-
dc.identifier.spage2941-
dc.identifier.epage2941-

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