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Article: Prevalence and determinants of SARS-CoV-2 vaccine hesitancy in Hong Kong: A population-based survey
Title | Prevalence and determinants of SARS-CoV-2 vaccine hesitancy in Hong Kong: A population-based survey |
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Authors | |
Keywords | Coronavirus COVID-19 Vaccine hesitancy Vaccine acceptance Chinese |
Issue Date | 2021 |
Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/vaccine |
Citation | Vaccine, 2021, v. 39 n. 27, p. 3602-3607 How to Cite? |
Abstract | Background: Although vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most desired solution to end the coronavirus disease (COVID-19) pandemic, there are growing concerns that vaccine hesitancy would undermine its potential. We examined the intention to receive vaccination against SARS-CoV-2 and the associated factors in a representative sample of Chinese adults in Hong Kong.
Methods: We did a dual-frame (landline and mobile) cross-sectional survey of a random sample of 1501 Hong Kong residents aged 18 years or older (53.6% females) in April 2020. We collected data on the intention to receive SARS-CoV-2 vaccine when it becomes available (yes/ no/ undecided), knowledge and perceptions of COVID-19, smoking, alcohol drinking, and sociodemographic factors. Prevalence estimates were weighted by the sex, age, and education of the general population of Hong Kong.
Results: Overall, 45.3% (95% CI: 42.3–48.4%) of the participants had intentions to vaccinate against SARS-CoV-2 when it becomes available, 29.2% (26.5–32.1%) were undecided, and 25.5% (22.9–28.2%) had no intention. The most common reason for vaccine hesitancy (undecided or no intention) was safety concerns (56.5%). Multivariable partial proportional odds model showed higher vaccine hesitancy in males, younger adults, those with no chronic disease, current smokers, and non-alcohol drinkers. After adjusting for sociodemographic and other factors, inadequate knowledge of SARS-CoV-2 transmission (adjusted ORs ranged from 1.27 to 2.63; P < 0.05) and lower perceived danger of COVID-19 (adjusted ORs ranged from 1.62 to 2.47; P < 0.001) were significantly associated with vaccine hesitancy.
Conclusions: In a representative sample of Chinese adults in Hong Kong, only 45.3% of the participants intended to vaccinate against SARS-CoV-2 when available. Vaccine hesitancy was associated with inadequate knowledge about SARS-CoV-2 transmission and lower perceived danger of COVID-19, which needed to be addressed to improve vaccination uptake. |
Persistent Identifier | http://hdl.handle.net/10722/301604 |
ISSN | 2023 Impact Factor: 4.5 2023 SCImago Journal Rankings: 1.342 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Luk, TT | - |
dc.contributor.author | Zhao, S | - |
dc.contributor.author | Wu, Y | - |
dc.contributor.author | Wong, JYH | - |
dc.contributor.author | Wang, MP | - |
dc.contributor.author | Lam, TH | - |
dc.date.accessioned | 2021-08-09T03:41:29Z | - |
dc.date.available | 2021-08-09T03:41:29Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Vaccine, 2021, v. 39 n. 27, p. 3602-3607 | - |
dc.identifier.issn | 0264-410X | - |
dc.identifier.uri | http://hdl.handle.net/10722/301604 | - |
dc.description.abstract | Background: Although vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most desired solution to end the coronavirus disease (COVID-19) pandemic, there are growing concerns that vaccine hesitancy would undermine its potential. We examined the intention to receive vaccination against SARS-CoV-2 and the associated factors in a representative sample of Chinese adults in Hong Kong. Methods: We did a dual-frame (landline and mobile) cross-sectional survey of a random sample of 1501 Hong Kong residents aged 18 years or older (53.6% females) in April 2020. We collected data on the intention to receive SARS-CoV-2 vaccine when it becomes available (yes/ no/ undecided), knowledge and perceptions of COVID-19, smoking, alcohol drinking, and sociodemographic factors. Prevalence estimates were weighted by the sex, age, and education of the general population of Hong Kong. Results: Overall, 45.3% (95% CI: 42.3–48.4%) of the participants had intentions to vaccinate against SARS-CoV-2 when it becomes available, 29.2% (26.5–32.1%) were undecided, and 25.5% (22.9–28.2%) had no intention. The most common reason for vaccine hesitancy (undecided or no intention) was safety concerns (56.5%). Multivariable partial proportional odds model showed higher vaccine hesitancy in males, younger adults, those with no chronic disease, current smokers, and non-alcohol drinkers. After adjusting for sociodemographic and other factors, inadequate knowledge of SARS-CoV-2 transmission (adjusted ORs ranged from 1.27 to 2.63; P < 0.05) and lower perceived danger of COVID-19 (adjusted ORs ranged from 1.62 to 2.47; P < 0.001) were significantly associated with vaccine hesitancy. Conclusions: In a representative sample of Chinese adults in Hong Kong, only 45.3% of the participants intended to vaccinate against SARS-CoV-2 when available. Vaccine hesitancy was associated with inadequate knowledge about SARS-CoV-2 transmission and lower perceived danger of COVID-19, which needed to be addressed to improve vaccination uptake. | - |
dc.language | eng | - |
dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/vaccine | - |
dc.relation.ispartof | Vaccine | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Coronavirus | - |
dc.subject | COVID-19 | - |
dc.subject | Vaccine hesitancy | - |
dc.subject | Vaccine acceptance | - |
dc.subject | Chinese | - |
dc.title | Prevalence and determinants of SARS-CoV-2 vaccine hesitancy in Hong Kong: A population-based survey | - |
dc.type | Article | - |
dc.identifier.email | Luk, TT: luktt@connect.hku.hk | - |
dc.identifier.email | Wu, Y: yongdang@connect.hku.hk | - |
dc.identifier.email | Wong, JYH: janetyh@hku.hk | - |
dc.identifier.email | Wang, MP: mpwang@hku.hk | - |
dc.identifier.email | Lam, TH: hrmrlth@hkucc.hku.hk | - |
dc.identifier.authority | Luk, TT=rp02827 | - |
dc.identifier.authority | Wong, JYH=rp01561 | - |
dc.identifier.authority | Wang, MP=rp01863 | - |
dc.identifier.authority | Lam, TH=rp00326 | - |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1016/j.vaccine.2021.05.036 | - |
dc.identifier.pmid | 34034950 | - |
dc.identifier.pmcid | PMC8130539 | - |
dc.identifier.scopus | eid_2-s2.0-85106600283 | - |
dc.identifier.hkuros | 323864 | - |
dc.identifier.volume | 39 | - |
dc.identifier.issue | 27 | - |
dc.identifier.spage | 3602 | - |
dc.identifier.epage | 3607 | - |
dc.identifier.isi | WOS:000659020000008 | - |
dc.publisher.place | United Kingdom | - |