File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Frontal QRS-T angle and ventricular mechanics in congenital heart disease

TitleFrontal QRS-T angle and ventricular mechanics in congenital heart disease
Authors
Issue Date2020
PublisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327
Citation
Heart and Vessels, 2020, v. 35, p. 1299-1306 How to Cite?
AbstractBackground: The QRS-T angle has been associated with adverse cardiovascular events and sudden cardiac deaths. We determined frontal QRS-T angle in patients with complete transposition of the great arteries (TGA) after atrial switch operation and repaired tetralogy of Fallot (TOF) and explored its relationships with ventricular mechanics. Methods: Thirty TGA patients aged 32.3 ± 4.4 years after atrial switch operation and 47 repaired TOF patients aged 28.7 ± 6.0 years were studied. The frontal planar QRS-T angle and QRS duration were measured from 12-lead electrocardiograms. Right (RV) and left ventricular (LV) strain parameters were determined using speckle tracking echocardiography. Results: Compared with TOF patients, TGA patients after atrial switch operation had significantly greater frontal QRS-T angle (136.3° ± 43.5° vs 74.5° ± 59.6°, p < 0.001), greater prevalence of QRS-T angle ≥ 100° (83.3% vs 29.8%, p < 0.001), and showed progressive increase in QRS-T angle over a duration of 3.3 ± 1.0 years (p = 0.035). The QRS-T angle correlated positively with QRS duration in both the TGA (r = 0.61, p < 0.001) and TOF (r = 0.30, p < 0.043) groups. Among TGA patients, QRS-T angle was found to correlate negatively with systemic RV global longitudinal strain (r = − 0.49, p = 0.007), early diastolic strain rate (r = − 0.41, p = 0.026), and fractional area change (r = − 0.38, p = 0.045), but not subpulmonary LV strain indices. By contrast, among repaired TOF patients, there were no significant correlations between QRS-T angle and systemic and subpulmonary ventricular strain indices (all p > 0.05). Conclusion: Increased frontal QRS-T angle is prevalent in TGA patients after atrial switch operation and is related to worse systemic RV mechanics.
Persistent Identifierhttp://hdl.handle.net/10722/290958
ISSN
2020 Impact Factor: 2.037
2015 SCImago Journal Rankings: 0.709
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, LY-
dc.contributor.authorSo, EKF-
dc.contributor.authorChow, PC-
dc.contributor.authorCheung, YF-
dc.date.accessioned2020-11-02T05:49:32Z-
dc.date.available2020-11-02T05:49:32Z-
dc.date.issued2020-
dc.identifier.citationHeart and Vessels, 2020, v. 35, p. 1299-1306-
dc.identifier.issn0910-8327-
dc.identifier.urihttp://hdl.handle.net/10722/290958-
dc.description.abstractBackground: The QRS-T angle has been associated with adverse cardiovascular events and sudden cardiac deaths. We determined frontal QRS-T angle in patients with complete transposition of the great arteries (TGA) after atrial switch operation and repaired tetralogy of Fallot (TOF) and explored its relationships with ventricular mechanics. Methods: Thirty TGA patients aged 32.3 ± 4.4 years after atrial switch operation and 47 repaired TOF patients aged 28.7 ± 6.0 years were studied. The frontal planar QRS-T angle and QRS duration were measured from 12-lead electrocardiograms. Right (RV) and left ventricular (LV) strain parameters were determined using speckle tracking echocardiography. Results: Compared with TOF patients, TGA patients after atrial switch operation had significantly greater frontal QRS-T angle (136.3° ± 43.5° vs 74.5° ± 59.6°, p < 0.001), greater prevalence of QRS-T angle ≥ 100° (83.3% vs 29.8%, p < 0.001), and showed progressive increase in QRS-T angle over a duration of 3.3 ± 1.0 years (p = 0.035). The QRS-T angle correlated positively with QRS duration in both the TGA (r = 0.61, p < 0.001) and TOF (r = 0.30, p < 0.043) groups. Among TGA patients, QRS-T angle was found to correlate negatively with systemic RV global longitudinal strain (r = − 0.49, p = 0.007), early diastolic strain rate (r = − 0.41, p = 0.026), and fractional area change (r = − 0.38, p = 0.045), but not subpulmonary LV strain indices. By contrast, among repaired TOF patients, there were no significant correlations between QRS-T angle and systemic and subpulmonary ventricular strain indices (all p > 0.05). Conclusion: Increased frontal QRS-T angle is prevalent in TGA patients after atrial switch operation and is related to worse systemic RV mechanics.-
dc.languageeng-
dc.publisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327-
dc.relation.ispartofHeart and Vessels-
dc.rightsAccepted Manuscript (AAM) This is a post-peer-review, pre-copyedit version of an article published in [insert journal title]. The final authenticated version is available online at: https://doi.org/[insert DOI]-
dc.titleFrontal QRS-T angle and ventricular mechanics in congenital heart disease-
dc.typeArticle-
dc.identifier.emailSo, EKF: edwinaso@hku.hk-
dc.identifier.emailCheung, YF: xfcheung@hku.hk-
dc.identifier.authorityCheung, YF=rp00382-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00380-020-01601-4-
dc.identifier.pmid32246195-
dc.identifier.scopuseid_2-s2.0-85082939119-
dc.identifier.hkuros317772-
dc.identifier.volume35-
dc.identifier.spage1299-
dc.identifier.epage1306-
dc.identifier.isiWOS:000523086600001-
dc.publisher.placeJapan-
dc.identifier.issnl0910-8327-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats