Cheung, YF

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Professor Cheung, Yiu Fai 張耀輝

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Clinical Professor
Bryan Lin Professor in Paediatric Cardiology

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Cheung, Yiu-fai

Biography
Professor Yiu-fai Cheung (張耀輝)
MBBS(HK), MD(HK), MRCP(UK), MRCPCH(UK), FHKCPaed, FHKAM(Paediatrics), FRCPCH(UK), FRCP(Edin)
 
Clinical Professor, Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong
(bestowed with the Endowed Professorship, Bryan Lin Professor in Paediatric Cardiology, in 2015)
 
Specialty
Paediatric Cardiology
 
Awards
Sir Patrick Manson Gold Medal (2004)
Faculty Teaching Medal (2007)
 
Biosketch
Dr Yiu-fai Cheung is a clinician specializing in paediatric cardiology, a teacher, and a clinician investigator.  His research interests include ventricular function in congenital and acquired heart diseases, vascular health, and ventriculo-arterial interaction.  He has written more than 150 peer-reviewed papers, 2 books, and 9 book chapters, produced a multimedia CD-ROM on diagnosis of congenital heart disease, and delivered more than 180 invited lectures.  Dr Cheung graduated from The University of Hong Kong in 1990, received his Doctorate of Medicine in 2004, and became a full professor in The University of Hong Kong in 2007.  In recognition of his excellence in medical education, he was awarded the Faculty Teaching Medal in 2007.  He is currently Bryan Lin Professor, Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
 
Research areas
Paediatric cardiology and adult congenital heart disease are the major areas of Professor Cheung's research.  The scope of research encompasses three domains: (i) paediatric and adult congenital heart disease, (ii) acquired heart disease in children, and (iii) vascular function in health and disease in the young.  His research work focuses on the followings:
  • Clinical translation and applications of novel echocardiographic imaging technologies
  • Cardiac and vascular mechanics in paediatric and adult congenital heart disease, iron overload and chemotherapy toxicity
  • Circulating biomarkers in congenital heart disease
  • Long-term clinical outcomes of paediatric congenital heart patients
  • Kawasaki disease: genetics and vascular health
Education
At the Faculty level, Professor Cheung is Chairman of the Board of Studies of Master of Medical Sciences programme.  At the Departmental level, he is member of the Education Committee and helps to coordinate undergraduate teachings of medical students.  Externally, he is member of the Examination Committee of Hong Kong College of Paediatricians. He serves as examiner of the MBBS examinations, MRCPCH clinical examination, and Licensing Examination of the Medical Council of Hong Kong. Professor YF Cheung is responsible for the teaching of paediatric cardiology to medical students, paediatric residents, and cardiology fellows.
 
Clinical Service
Professor YF Cheung provides specialist clinical service for children and adults with congenital and children with acquired heart diseases.  Together with other paediatric cardiologists atQueen Mary Hospital, they provide comprehensive diagnostic evaluation, postoperative care, and transcatheter interventions for patients ranging from neonates with critical heart conditions to grown-up congenital heart patients.
 
Selected Publications

Novel echocardiographic imaging technologies

  • To AH, Li VW, Ng MY, Cheung YF. Quantification of pulmonary regurgitation  by vector flow mapping in congenital heart patients after repair of right ventricular  outflow obstruction: A preliminary study. J Am Soc Echocardiogr 2017;30:984-991. 
  • Li SJ, Hwang YY, Ha SY, Chan GCF, Mok ASP, Wong SJ, Cheung YF. Role of three-dimensional speckle tracking echocardiography in the quantification of myocardial iron overload in patients with beta-thalassemia major. Echocardiography 2016;33:1361-1367. 
  • Yu HK, Yu W, Cheuk DK, Wong SJ, Chan CF, Cheung YF.  New three-dimensional speckle-tracking echocardiography identities global impairment of left ventricular mechanics with a high sensitivity in childhood cancer survivors.  Journal of the American Society of Echocardiography 2013;26:846-852.
  • Cheung YF.  The role of 3D wall motion tracking in heart failure.  Nature Reviews Cardiology 2012;9:644-657. 
  • Li SN, Wong SJ, Cheung YF.  Novel area strain based on three-dimensional wall motion analysis for assessment of global left ventricular performance after repair of tetralogy of Fallot.  Journal of the American Society of Echocardiography 2011;24:819-825. 

Cardiac and vascular mechanics

  • Li VWY, Cheung YF.  Right ventricular myocardial motion and deformation in adolescents and young adults after repair of coarctation of the aorta.  Echocardiography 2015;32:797-804.  
  • Yu W, Wong SJ, Cheung YF.  Left ventricular mechanics in adolescents and young adults with a history of Kawasaki Disease: analysis by 3D speckle tracking echocardiography.  Echocardiography 2014;31:483-491. 
  • Cheung YF, Hong WJ, Chan GCF, Wong SJ, Ha SY.  Left ventricular myocardial deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy.  Heart 2010;96:1137-1141. 
  • Cheung YF, Chan CF, Ha SY.  Arterial stiffness and endothelial function in patients with beta-thalassaemia major.  Circulation 2002;106;2561-2566. 
  • Cheung YF, Taylor MJ, Fisk NM, Redington AN, Gardiner HM.  Fetal origins of reduced arterial distensibility in the donor twin in twin-twin transfusion syndrome.  Lancet 2000;355:1157-1158. 

Kawasaki disease

  • Khor CC, Davila S, Breunis WB, Lee YC, Shimizu C, Wright VJ, Yeung RS, Tan DE, Sim KS, Wang JJ, Wong TY, Pang J, Mitchell P, Cimaz R, Dahdah N, Cheung YF, Huang GY, Yang W, Park IS, Lee JK, Wu JY, Levin M, Burns JC, Burgner D, Kuijpers TW, Hibberd ML; Hong Kong–Shanghai Kawasaki Disease Genetics Consortium, Lau YL, Zhang J, Ma XJ, Liu F, Wu L; Korean Kawasaki Disease Genetics Consortium, Yoo JJ, Hong SJ, Kim KJ , Kim JJ, Park YM, Hong YM, Sohn S, Jang GY, Ha KS, Nam HK, Byeon JH, Yun SW, Han MK, Lee KY, Hwang JY, Rhim JW, Song MS, Lee HD, Kim DS, Lee JM; Taiwan Kawasaki Disease Genetics Consortium, Chang JS, Tsai FJ, Liang CD, Chen MR, Chi H, Chiu NC, Huang FY, Chang LY, Huang LM, Kuo HC, Huang KP, Lee ML, Hwang B, Huang YC, Lee PC; International Kawasaki Disease Genetics Consortium, Odam M, Christiansen FT, Witt C, Goldwater P, Curtis N, Palasanthiran P, Ziegler J, Nissen M, Nourse C, Kuipers IM, Ottenkamp JJ, Geissler J, Biezeveld M, Tacke C, Filippini L, Brogan P, Klein N, Shah V, Dillon M, Booy R, Shingadia D, Bose A, Mukasa T, Tulloh R, Michie C; US Kawasaki Disease Genetics Consortium, Newburger JW, Baker AL, Rowley AH, Shulman ST, Mason W, Takahashi M, Melish ME, Tremoulet AH; Blue Mountains Eye Study, Viswanathan A, Rochtchina E, Attia J, Scott R, Holliday E, Harrap S. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nature Genetics 2011;43:1241-1246. 
  • Cheung YF, Huang GY, Chen SB, Liu XQ , Xi L, Liang XC, Huang MR, Chen S, Huang LS, Liu XQ, Chan KW, Lau YL.  Inflammatory gene polymorphisms and susceptibility to Kawasaki disease and its arterial sequelae.  Pediatrics 2008;122:608-614. 
  • Cheung YF, Ho MHK, Tam SCF, Yung TC.  Increased high sensitivity C reactive protein concentrations and increased arterial stiffness in children with a history of Kawasaki disease.  Heart 2004;90:1281-1285. 
  • Cheung YF, Yung TC, Tam SC, Ho MH, Chau AKT.  Novel and traditional cardiovascular risk factors in children after Kawasaki disease: Implications for premature atherosclerosis.  Journal of the American College of Cardiology 2004;43:120-124. 
 
Honours, Awards & Prizes
Professional Societies
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