File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: CLINICAL CORRELATES OF SUBJECTIVE QUALITY OF LIFE IN ADULT PATIENTS WITH EARLY PSYCHOSIS IN HONG KONG

TitleCLINICAL CORRELATES OF SUBJECTIVE QUALITY OF LIFE IN ADULT PATIENTS WITH EARLY PSYCHOSIS IN HONG KONG
Authors
Issue Date2020
PublisherOxford University Press. The Journal's web site is located at http://schizophreniabulletin.oxfordjournals.org/
Citation
Congress of the Schizophrenia International Research Society (SIRS) 2020, Florence, Italy, 4-8 April 2020. In Schizophrenia Bulletin, 2020, v. 46 n. Suppl. 1, p. S211, abstract no. M196 How to Cite?
AbstractBackground: Subjective quality of life (SQoL) is an important outcome domain in patients with early psychosis. In an attempt to better understand and maximize SQoL of early psychosis patients, an increasing number of research has been conducted to investigate factors associated with SQoL. Nonetheless, most previous studies focused on younger patients with early psychosis. In this study, the correlates of SQoL in adult patients who had completed 3-year specialized early intervention service for first-episode psychosis (FEP) in Hong Kong were investigated. Methods: In total, one hundred and one Chinese patients aged 26–55 years who completed 3-year specialized early intervention service for psychosis in Hong Kong were recruited. Assessments on illness onset (DUP), clinical (PANSS, BNSS, SUMD), intrinsic motivation (by items in Quality of Life Scale, QLS), functional (SOFAS), antipsychotic-induced parkinsonism features (Simpson-Angus Scale, SAS) were conducted. SQoL was evaluated by Chinese version SF-12 which consist of physical and mental components for analysis. Results: Correlation analyses showed that SF12 physical health score was correlated with PANSS depression component (p<0.001), QLS intrinsic motivation score (p=0.001) and SAS score (p<0.05) while SF12 mental health score was correlated with PANSS depression score (p<0.001), QLS intrinsic motivation score (p<0.05) and SAS score (p<0.05). Multiple linear regression analyses further revealed that lower PANSS depression score (p<0.001) and higher intrinsic motivation (measured by QLS, p<0.05) were independently associated with better physical SQoL, while lower PANSS depression score (p<0.001) and lower SAS side-effect score (p<0.05) were independently related to better mental SQoL. Discussion: Our results are consistent with the literature which indicates that SQoL is significantly related to depressive symptoms. In addition, patients with higher intrinsic motivation and less antipsychotic-induced extrapyramidal side-effect have better SQoL. Further analysis on the longitudinal data will clarify variables predictive of SQoL at follow-up.
DescriptionPoster Session II - no. M196
Congress was cancelled due to COVID-19
Persistent Identifierhttp://hdl.handle.net/10722/290229
ISSN
2023 Impact Factor: 5.3
2023 SCImago Journal Rankings: 2.249

 

DC FieldValueLanguage
dc.contributor.authorKam, CTK-
dc.contributor.authorLau, FC-
dc.contributor.authorLui, TT-
dc.contributor.authorWong, SMC-
dc.contributor.authorHui, CLM-
dc.contributor.authorChan, KW-
dc.contributor.authorLee, HME-
dc.contributor.authorSuen, YN-
dc.contributor.authorChen, EYH-
dc.contributor.authorChang, WC-
dc.date.accessioned2020-10-22T08:23:50Z-
dc.date.available2020-10-22T08:23:50Z-
dc.date.issued2020-
dc.identifier.citationCongress of the Schizophrenia International Research Society (SIRS) 2020, Florence, Italy, 4-8 April 2020. In Schizophrenia Bulletin, 2020, v. 46 n. Suppl. 1, p. S211, abstract no. M196-
dc.identifier.issn0586-7614-
dc.identifier.urihttp://hdl.handle.net/10722/290229-
dc.descriptionPoster Session II - no. M196-
dc.descriptionCongress was cancelled due to COVID-19-
dc.description.abstractBackground: Subjective quality of life (SQoL) is an important outcome domain in patients with early psychosis. In an attempt to better understand and maximize SQoL of early psychosis patients, an increasing number of research has been conducted to investigate factors associated with SQoL. Nonetheless, most previous studies focused on younger patients with early psychosis. In this study, the correlates of SQoL in adult patients who had completed 3-year specialized early intervention service for first-episode psychosis (FEP) in Hong Kong were investigated. Methods: In total, one hundred and one Chinese patients aged 26–55 years who completed 3-year specialized early intervention service for psychosis in Hong Kong were recruited. Assessments on illness onset (DUP), clinical (PANSS, BNSS, SUMD), intrinsic motivation (by items in Quality of Life Scale, QLS), functional (SOFAS), antipsychotic-induced parkinsonism features (Simpson-Angus Scale, SAS) were conducted. SQoL was evaluated by Chinese version SF-12 which consist of physical and mental components for analysis. Results: Correlation analyses showed that SF12 physical health score was correlated with PANSS depression component (p<0.001), QLS intrinsic motivation score (p=0.001) and SAS score (p<0.05) while SF12 mental health score was correlated with PANSS depression score (p<0.001), QLS intrinsic motivation score (p<0.05) and SAS score (p<0.05). Multiple linear regression analyses further revealed that lower PANSS depression score (p<0.001) and higher intrinsic motivation (measured by QLS, p<0.05) were independently associated with better physical SQoL, while lower PANSS depression score (p<0.001) and lower SAS side-effect score (p<0.05) were independently related to better mental SQoL. Discussion: Our results are consistent with the literature which indicates that SQoL is significantly related to depressive symptoms. In addition, patients with higher intrinsic motivation and less antipsychotic-induced extrapyramidal side-effect have better SQoL. Further analysis on the longitudinal data will clarify variables predictive of SQoL at follow-up.-
dc.languageeng-
dc.publisherOxford University Press. The Journal's web site is located at http://schizophreniabulletin.oxfordjournals.org/-
dc.relation.ispartofSchizophrenia Bulletin-
dc.relation.ispartofCongress of the Schizophrenia International Research Society (SIRS) 2020-
dc.titleCLINICAL CORRELATES OF SUBJECTIVE QUALITY OF LIFE IN ADULT PATIENTS WITH EARLY PSYCHOSIS IN HONG KONG-
dc.typeConference_Paper-
dc.identifier.emailWong, SMC: wongcsm@hku.hk-
dc.identifier.emailHui, CLM: christyh@hku.hk-
dc.identifier.emailChan, KW: kwsherry@hku.hk-
dc.identifier.emailLee, HME: edwinlhm@hku.hk-
dc.identifier.emailSuen, YN: suenyn@hku.hk-
dc.identifier.emailChen, EYH: eyhchen@hku.hk-
dc.identifier.emailChang, WC: changwc@hku.hk-
dc.identifier.authorityWong, SMC=rp02625-
dc.identifier.authorityHui, CLM=rp01993-
dc.identifier.authorityChan, KW=rp00539-
dc.identifier.authorityLee, HME=rp01575-
dc.identifier.authoritySuen, YN=rp02481-
dc.identifier.authorityChen, EYH=rp00392-
dc.identifier.authorityChang, WC=rp01465-
dc.description.natureabstract-
dc.identifier.doi10.1093/schbul/sbaa030.508-
dc.identifier.hkuros316951-
dc.identifier.volume46-
dc.identifier.issueSuppl. 1-
dc.identifier.spageS211, abstract no. M196-
dc.identifier.epageS211, abstract no. M196-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl0586-7614-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats