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Article: A Crowdsourced Intervention To Promote Hepatitis B And C Testing Among Men Who Have Sex With Men In China: A Nationwide Online Randomized Controlled Trial
Title | A Crowdsourced Intervention To Promote Hepatitis B And C Testing Among Men Who Have Sex With Men In China: A Nationwide Online Randomized Controlled Trial |
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Authors | |
Keywords | adult China controlled study crowdsourcing disease burden |
Issue Date | 2019 |
Publisher | Elsevier Ltd. The Journal's web site is located at https://www.journals.elsevier.com/eclinicalmedicine |
Citation | EClinicalMedicine, 2019, v. 16, p. 64-73 How to Cite? |
Abstract | Background: Crowdsourcing may be an effective strategy to develop test promotion materials. We conducted an online randomized controlled trial (RCT) to evaluate a crowdsourced intervention to promote hepatitis B virus (HBV) and hepatitis C virus (HCV) testing among men who have sex with men (MSM) in China. Methods: MSM never previously tested for hepatitis were recruited through social media. Eligible men were randomized to receive an online crowdsourced intervention or no testing promotion materials. Outcomes including self-reported and confirmed HBV and HCV test uptake were assessed after four weeks. Odds ratios (OR) with 95% confidence intervals (95% CI) of men achieving primary and secondary outcomes between the intervention and control arms were calculated. Findings: 556 eligible men were enrolled. Overall, 17•4% (97/556) of men self-reported HBV and HCV testing and 7•9% (44/556) confirmed HBV and HCV test uptake. The intervention was seen by 72•1% and 29•0% of men in the intervention and control arms, respectively. In intention-to-treat analysis, confirmed HBV and HCV test uptake was similar between the two arms, both when using a missing=failure approach (OR 0•98, 95% CI 0•53–1•82) or multiple imputation (OR 1•46, 95% CI 0•72–2•95). Interpretation: This RCT extends the literature by developing and evaluating an intervention to spur hepatitis testing in a middle-income country with a high burden of hepatitis. Overall test uptake among MSM in China was similar to previous interventions promoting hepatitis testing in high-income countries. We found frequent intervention sharing, complicating interpretation of the results, and the role of crowdsourcing to promote hepatitis testing remains unclear. |
Persistent Identifier | http://hdl.handle.net/10722/282006 |
ISSN | 2023 Impact Factor: 9.6 2023 SCImago Journal Rankings: 3.522 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Fitzpatrick, T | - |
dc.contributor.author | Tang, W | - |
dc.contributor.author | Mollan, K | - |
dc.contributor.author | Pan, X | - |
dc.contributor.author | Chan, P-L | - |
dc.contributor.author | Zhou, K-L | - |
dc.contributor.author | Cheng, Y | - |
dc.contributor.author | Li, L-H | - |
dc.contributor.author | Wong, WCW | - |
dc.contributor.author | Tucker, JD | - |
dc.date.accessioned | 2020-04-19T03:34:02Z | - |
dc.date.available | 2020-04-19T03:34:02Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | EClinicalMedicine, 2019, v. 16, p. 64-73 | - |
dc.identifier.issn | 2589-5370 | - |
dc.identifier.uri | http://hdl.handle.net/10722/282006 | - |
dc.description.abstract | Background: Crowdsourcing may be an effective strategy to develop test promotion materials. We conducted an online randomized controlled trial (RCT) to evaluate a crowdsourced intervention to promote hepatitis B virus (HBV) and hepatitis C virus (HCV) testing among men who have sex with men (MSM) in China. Methods: MSM never previously tested for hepatitis were recruited through social media. Eligible men were randomized to receive an online crowdsourced intervention or no testing promotion materials. Outcomes including self-reported and confirmed HBV and HCV test uptake were assessed after four weeks. Odds ratios (OR) with 95% confidence intervals (95% CI) of men achieving primary and secondary outcomes between the intervention and control arms were calculated. Findings: 556 eligible men were enrolled. Overall, 17•4% (97/556) of men self-reported HBV and HCV testing and 7•9% (44/556) confirmed HBV and HCV test uptake. The intervention was seen by 72•1% and 29•0% of men in the intervention and control arms, respectively. In intention-to-treat analysis, confirmed HBV and HCV test uptake was similar between the two arms, both when using a missing=failure approach (OR 0•98, 95% CI 0•53–1•82) or multiple imputation (OR 1•46, 95% CI 0•72–2•95). Interpretation: This RCT extends the literature by developing and evaluating an intervention to spur hepatitis testing in a middle-income country with a high burden of hepatitis. Overall test uptake among MSM in China was similar to previous interventions promoting hepatitis testing in high-income countries. We found frequent intervention sharing, complicating interpretation of the results, and the role of crowdsourcing to promote hepatitis testing remains unclear. | - |
dc.language | eng | - |
dc.publisher | Elsevier Ltd. The Journal's web site is located at https://www.journals.elsevier.com/eclinicalmedicine | - |
dc.relation.ispartof | EClinicalMedicine | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | adult | - |
dc.subject | China | - |
dc.subject | controlled study | - |
dc.subject | crowdsourcing | - |
dc.subject | disease burden | - |
dc.title | A Crowdsourced Intervention To Promote Hepatitis B And C Testing Among Men Who Have Sex With Men In China: A Nationwide Online Randomized Controlled Trial | - |
dc.type | Article | - |
dc.identifier.email | Wong, WCW: wongwcw@hku.hk | - |
dc.identifier.authority | Wong, WCW=rp01457 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1016/j.eclinm.2019.10.007 | - |
dc.identifier.scopus | eid_2-s2.0-85075440861 | - |
dc.identifier.hkuros | 309726 | - |
dc.identifier.volume | 16 | - |
dc.identifier.spage | 64 | - |
dc.identifier.epage | 73 | - |
dc.identifier.isi | WOS:000646548500017 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 2589-5370 | - |