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Article: Prediction of self-stigma in early psychosis: 3-Year follow-up of the randomized-controlled trial on extended early intervention

TitlePrediction of self-stigma in early psychosis: 3-Year follow-up of the randomized-controlled trial on extended early intervention
Authors
KeywordsSelf-stigma
Internalized stigma
Duration of untreated psychosis
Early psychosis
Longitudinal follow-up
Issue Date2018
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
Schizophrenia Research, 2018, v. 195, p. 463-468 How to Cite?
AbstractBACKGROUND: Self-stigma represents a major barrier to recovery in people with psychotic disorders but is understudied in early illness stage. Longitudinal investigation of prediction for self-stigma is scarce and none is conducted in early psychosis. We aimed to prospectively examine baseline predictors of self-stigma in early psychosis patients in the context of a 3-year follow-up of a randomized-controlled trial (RCT) comparing 1-year extension of early intervention (EI) with step-down psychiatric care for first-episode psychosis (FEP). METHOD: One hundred sixty Chinese patients were recruited from a specialized EI program for FEP in Hong Kong after they had completed this 2-year EI service, and underwent a 12-month RCT. Participants were followed up and reassessed 3years after inclusion to the trial. Comprehensive evaluation encompassing clinical, functional, subjective quality of life and treatment-related variables were conducted. Data analysis was based on 136 participants who completed self-stigma assessment at 3-year follow-up. RESULTS: Fifty patients (36.8%) had moderate to high levels of self-stigma at 3-year follow-up. Multivariate regression analysis revealed that female gender, prior psychiatric hospitalization, longer duration of untreated psychosis and greater positive symptom severity at study intake independently predicted self-stigma at the end of 3-year study period. CONCLUSION: Our results of more than one-third of early psychosis patients experienced significant self-stigma underscore the clinical needs for early identification and intervention of self-stigmatization in the initial years of psychotic illness. Further research is warranted to clarify prediction profile and longitudinal course of self-stigma in the early illness phase.
Persistent Identifierhttp://hdl.handle.net/10722/251800
ISSN
2020 Impact Factor: 4.939
2020 SCImago Journal Rankings: 1.923
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, RWH-
dc.contributor.authorChang, WC-
dc.contributor.authorKwong, WY-
dc.contributor.authorLau, SK-
dc.contributor.authorChan, GHK-
dc.contributor.authorJim, OTT-
dc.contributor.authorHui, CLM-
dc.contributor.authorChan, KW-
dc.contributor.authorLee, HME-
dc.contributor.authorChen, EYH-
dc.date.accessioned2018-03-19T07:01:27Z-
dc.date.available2018-03-19T07:01:27Z-
dc.date.issued2018-
dc.identifier.citationSchizophrenia Research, 2018, v. 195, p. 463-468-
dc.identifier.issn0920-9964-
dc.identifier.urihttp://hdl.handle.net/10722/251800-
dc.description.abstractBACKGROUND: Self-stigma represents a major barrier to recovery in people with psychotic disorders but is understudied in early illness stage. Longitudinal investigation of prediction for self-stigma is scarce and none is conducted in early psychosis. We aimed to prospectively examine baseline predictors of self-stigma in early psychosis patients in the context of a 3-year follow-up of a randomized-controlled trial (RCT) comparing 1-year extension of early intervention (EI) with step-down psychiatric care for first-episode psychosis (FEP). METHOD: One hundred sixty Chinese patients were recruited from a specialized EI program for FEP in Hong Kong after they had completed this 2-year EI service, and underwent a 12-month RCT. Participants were followed up and reassessed 3years after inclusion to the trial. Comprehensive evaluation encompassing clinical, functional, subjective quality of life and treatment-related variables were conducted. Data analysis was based on 136 participants who completed self-stigma assessment at 3-year follow-up. RESULTS: Fifty patients (36.8%) had moderate to high levels of self-stigma at 3-year follow-up. Multivariate regression analysis revealed that female gender, prior psychiatric hospitalization, longer duration of untreated psychosis and greater positive symptom severity at study intake independently predicted self-stigma at the end of 3-year study period. CONCLUSION: Our results of more than one-third of early psychosis patients experienced significant self-stigma underscore the clinical needs for early identification and intervention of self-stigmatization in the initial years of psychotic illness. Further research is warranted to clarify prediction profile and longitudinal course of self-stigma in the early illness phase.-
dc.languageeng-
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres-
dc.relation.ispartofSchizophrenia Research-
dc.rightsPosting accepted manuscript (postprint): © <year>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/-
dc.subjectSelf-stigma-
dc.subjectInternalized stigma-
dc.subjectDuration of untreated psychosis-
dc.subjectEarly psychosis-
dc.subjectLongitudinal follow-up-
dc.titlePrediction of self-stigma in early psychosis: 3-Year follow-up of the randomized-controlled trial on extended early intervention-
dc.typeArticle-
dc.identifier.emailChang, WC: changwc@hku.hk-
dc.identifier.emailHui, CLM: christyh@hku.hk-
dc.identifier.emailChan, KW: kwsherry@hku.hk-
dc.identifier.emailLee, HME: edwinlhm@hku.hk-
dc.identifier.emailChen, EYH: eyhchen@hku.hk-
dc.identifier.authorityChang, WC=rp01465-
dc.identifier.authorityHui, CLM=rp01993-
dc.identifier.authorityChan, KW=rp00539-
dc.identifier.authorityLee, HME=rp01575-
dc.identifier.authorityChen, EYH=rp00392-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.schres.2017.09.004-
dc.identifier.pmid28888358-
dc.identifier.scopuseid_2-s2.0-85031019619-
dc.identifier.hkuros284520-
dc.identifier.volume195-
dc.identifier.spage463-
dc.identifier.epage468-
dc.identifier.isiWOS:000432466700070-
dc.publisher.placeNetherlands-
dc.identifier.issnl0920-9964-

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