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  Patent History
  • Application
    US 12/4334781 2014-07-18
  • Granted
    US 20150025339 2015-01-22
  Patent Family

granted patent: Methods for Classifying Pleural Fluid

TitleMethods for Classifying Pleural Fluid
Granted PatentUS 20150025339
Granted Date2015-01-22
Priority Date2013-07-18 US 12/1847610P
2014-07-18 US 12/4334781
Inventors
Issue Date2015
Citation
US Patent US 20150025339. Washington, DC: US Patent and Trademark Office (USPTO), 2015 How to Cite?
AbstractMethods of classifying pleural fluid are disclosed. The methods typically include determining the level of indicator nanoparticles, such as lipids, particularly large lipids, in the pleural fluid of a subject. The level of lipids can be determined by nuclear magnetic resonance (NMR), such as proton NMR (1H-NMR) by measuring the NMR signal corresponding to methyl protons, methylene protons, methene protons, or combinations thereof. The level of large lipids in pleural fluid can be carried out in vitro on a sample of pleural fluid obtained from the subject or in vivo using magnetic resonance spectroscopy (MRS). The pleural fluid can be classified as exudate or transudate with a sensitivity, selectivity, or combination thereof of 85%, 90%, 95%, 99%, or higher, a selectivity of 85%, 90%, 95%, 99%. The method can be coupled with diagnosing and/or treating the subject with a disease, disorder, or condition.
Persistent Identifierhttp://hdl.handle.net/10722/210488

 

DC FieldValueLanguage
dc.date.accessioned2015-06-17T07:02:33Z-
dc.date.available2015-06-17T07:02:33Z-
dc.date.issued2015-
dc.identifier.citationUS Patent US 20150025339. Washington, DC: US Patent and Trademark Office (USPTO), 2015-
dc.identifier.urihttp://hdl.handle.net/10722/210488-
dc.description.abstractMethods of classifying pleural fluid are disclosed. The methods typically include determining the level of indicator nanoparticles, such as lipids, particularly large lipids, in the pleural fluid of a subject. The level of lipids can be determined by nuclear magnetic resonance (NMR), such as proton NMR (1H-NMR) by measuring the NMR signal corresponding to methyl protons, methylene protons, methene protons, or combinations thereof. The level of large lipids in pleural fluid can be carried out in vitro on a sample of pleural fluid obtained from the subject or in vivo using magnetic resonance spectroscopy (MRS). The pleural fluid can be classified as exudate or transudate with a sensitivity, selectivity, or combination thereof of 85%, 90%, 95%, 99%, or higher, a selectivity of 85%, 90%, 95%, 99%. The method can be coupled with diagnosing and/or treating the subject with a disease, disorder, or condition.-
dc.titleMethods for Classifying Pleural Fluid-
dc.typePatent-
dc.identifier.authorityLAM CHING-WAN=rp00260-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorLAM CHING-WAN-
patents.identifier.applicationUS 12/4334781-
patents.identifier.grantedUS 20150025339-
patents.description.assigneeUNIV HONG KONG [HK] -
patents.description.countryUnited States of America -
patents.date.granted2015-01-22-
patents.identifier.hkutechidPath-2013-00470-1-
patents.date.application2014-07-18-
patents.date.priority2013-07-18 US 12/1847610P-
patents.date.priority2014-07-18 US 12/4334781-
patents.description.ccus-
patents.relation.familyWO 2015007192 (A1) 2015-01-22-
patents.description.kindA1-
patents.typePatent_granted-

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