Name Card
rp00260 picture

Professor Lam, Ching Wan 林青雲

Title:
Clinical Professor of Practice
Clinical Professor of Pathology Practice

Biography

Professor Lam obtained his MBChB from The Chinese University of Hong Kong in 1991 and FRCPA in 1997 from The Royal College of Pathologists of Australasia with a double scope of practice in Chemical Pathology and Genetics. He is a Fellow of The Australasian Association of Clinical Bicohemists. He obtained his PhD in 2000 from The Chinese University of Hong Kong. He obtained FRCP(Glas) from The Royal College of Physicians and Surgeons of Glasgow in 2012.

 

Professor Ching-Wan Lam is a chemical pathologist with 20 years experiences in inherited metabolic disease and has over 160 publications on this subject. His research interests include various aspects of inherited metabolic diseases and genetic testing. For example, he identified the MECP2 gene, the first disease gene for non-syndromic infantile autism. The locus is called AUTSX3 (AUTISM, X-LINKED, SUSCEPTIBILITY TO, 3; MIM ID #300496). This work has been incorporated in the formulation of an international guideline for etiologic diagnosis of autism, i.e, The American College of Medical Genetics 2013 clinical practice guideline.

 

He identified the SMOOTHENED gene to be the driver gene in sporadic medulloblastomas. This work has provided important leads for development of SMOOTHENED inhibitor Vismodegibs.  He also identified a new pharmacogenetic disease in which valproate, a first-line anti-epilepsy drug, can trigger onset of Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like episodes (MELAS). This work has lead to a change in clinical practice that valproate is now contraindicated to patients with mitochondrial DNA disease by Food and Drug Administration (FDA),The United States of America (http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm360487.htm).

 

Professor Ching-Wan Lam is The Editor, Clinical Chimica Acta, an official journal of The International Federation of Clinical Chemistry and Laboratory Medicine.

 
Honours, Awards & Prizes
AwardeesAward DateHonours / Awards / PrizesCategory
2018-04-01The Best Poster Award: The 11th International Conference of Clinical Laboratory Automation and Robotics, 19- 21 April 2018, Morioka, Japan
Research Achievement
2020-10-01Reviewer’s Choice Award: American Society of Human Genetics Virtual Meeting 2020, 27-30 October 2020
Research Achievement
2015-12-01Best Research Output Prize 2015, Strategic Research Themes – Development and Reproduction, HKU: Symposium on Stem Cells, Reproduction, Development and Disease 2015
Research Achievement
2016-05-01Outstanding Team, Queen Mary Hospital and The Duchess of Kent Children's Hospital at Sandy Bay (Hong Kong West Cluster), Testing for neuromuscular disease: 2016 Outstanding Staff and Teams Award
Others
2022-03-01HKWC and QMH/TYH Outstanding Teams Division of Chemical Pathology, QMH: HKWC and QMH/TYH Outstanding Staff & Teams Award and Young Achievers Award 2022
Others
Cheung, KK
Lee, KC
2013-07-01Springer Poster Prize For Outstanding Poster Presentation Of Research In The Field Of Metabolomics In The Metabolomics Society 2013 Conference: Metabolomics Society 2013 Conference
Research Achievement
2015-02-01Board of Education and Assessment Poster Prize (runner up) in Pathology Update 2015 (Melbourne).: The Royal College of Pathologists of Australasia (RCPA).
Research Achievement
2015-02-01Winner of Roche Scientific Display, Chemical Pathology (Co-author) in Pathology Update 2015 (Melbourne).: The Royal College of Pathologists in Australasia (RCPA).
Research Achievement
Professional Societies
Term PeriodPositionProfessional Societies
2015Selection Board Examiner in Clinical Pathology for assessing medical staff for promotion to consultant grades within the governmentThe Health Bureau, The Macao Special Administrative Region
2010-presentFounding Assessor, Chemical Pathology and GeneticsHong Kong Accreditation Service
2017-presentFounding Member of Task Force on Next Generation sequencingHong Kong Accreditation Service
09/2008-presentChief ExaminerHong Kong College of Pathologists
09/2013-presentExpert Advisory Group on Bioavailability and Bioequivalence StudiesPharmacy and Poisons Board Hong Kong
03/02/2009-04/02/2009ObserverHong Kong Accreditation Service
07/2013-06/2016Member of Task Force on Medical GeneticsHong Kong Accreditation Service
2010AssessorHong Kong Government Body - Professional Services for HOKLAS
2007-2013External ExaminerAustralian Association of Clinical Biochemists
Loading Content...Please Wait!
Loading Content...Please Wait!
Loading Content...Please Wait!
Loading Content...Please Wait!
Loading Content...Please Wait!
Loading Content...Please Wait!
Loading Content...Please Wait!