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Conference Paper: Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells
Title | Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells |
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Authors | |
Keywords | Medical sciences |
Issue Date | 2014 |
Publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk |
Citation | The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1, p. 34, abstract no. 52 How to Cite? |
Abstract | INTRODUCTION: Serotonin (5-hydrotrytamine, 5-HT) plays an important role in pulmonary functions. It is synthesised from tryptophan by aromatic 1-amino acid decarboxylase (AADC) and released at the sites, which binds to 5-HT receptors at the postsynaptic ends. Excess or turnover 5-HT will be recycled back into cells via 5-HT reuptake transporter (SERT), stored or subsequently metabolised by monoamine oxidase A (MAO-A) inside the cells. With the influence of smoking on serotoninergic neurons, we hypothesised that there may be a potential 5-HT analogue in cigarette smoke. We aimed to study the effect of 5-HT on interleukin (IL)–8 release and the effects of cigarette smoke on the metabolism of 5-HT in human bronchial epithelial … |
Persistent Identifier | http://hdl.handle.net/10722/204303 |
ISSN | 2023 Impact Factor: 3.1 2023 SCImago Journal Rankings: 0.261 |
DC Field | Value | Language |
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dc.contributor.author | Mak, JCW | en_US |
dc.contributor.author | Lau, WKW | en_US |
dc.contributor.author | Ip, MSM | en_US |
dc.date.accessioned | 2014-09-19T21:43:26Z | - |
dc.date.available | 2014-09-19T21:43:26Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1, p. 34, abstract no. 52 | en_US |
dc.identifier.issn | 1024-2708 | - |
dc.identifier.uri | http://hdl.handle.net/10722/204303 | - |
dc.description.abstract | INTRODUCTION: Serotonin (5-hydrotrytamine, 5-HT) plays an important role in pulmonary functions. It is synthesised from tryptophan by aromatic 1-amino acid decarboxylase (AADC) and released at the sites, which binds to 5-HT receptors at the postsynaptic ends. Excess or turnover 5-HT will be recycled back into cells via 5-HT reuptake transporter (SERT), stored or subsequently metabolised by monoamine oxidase A (MAO-A) inside the cells. With the influence of smoking on serotoninergic neurons, we hypothesised that there may be a potential 5-HT analogue in cigarette smoke. We aimed to study the effect of 5-HT on interleukin (IL)–8 release and the effects of cigarette smoke on the metabolism of 5-HT in human bronchial epithelial … | - |
dc.language | eng | en_US |
dc.publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk | - |
dc.relation.ispartof | Hong Kong Medical Journal | en_US |
dc.rights | Hong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Medical sciences | - |
dc.title | Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Mak, JCW: judithmak@hku.hk | en_US |
dc.identifier.email | Lau, WKW: wayhku@hkucc.hku.hk | en_US |
dc.identifier.email | Ip, MSM: msmip@hku.hk | en_US |
dc.identifier.authority | Mak, JCW=rp00352 | en_US |
dc.identifier.authority | Ip, MSM=rp00347 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.hkuros | 240407 | en_US |
dc.identifier.volume | 20 | en_US |
dc.identifier.issue | suppl. 1 | en_US |
dc.identifier.spage | 34 | en_US |
dc.identifier.epage | 34 | en_US |
dc.publisher.place | Hong Kong | - |
dc.identifier.issnl | 1024-2708 | - |