Name Card
Dr Judith Mak 麥翠和
Title:
Principal Lecturer
Department:
Faculty:
Contact Information
Dr Judith Mak 麥翠和
Title:
Principal Lecturer
Department:
Faculty:
Curriculum Vitae:
Research Interests:(click to check for cognate researchers)
- Investigating the effects of specific pathway inhibitors on the primary cell response to inflammation in the airway epithelium.
- Elucidation of pathophysiological pathways in rodent models of chronic airway diseases such as chronic obstructive pulmonary disease (COPD) (i.e. cigarette smoke-exposed rat model or ozone-exposed mouse model), asthma (i.e. ovalbumin sensitized allergen challenged mouse model), and obstructive sleep apnea (OSA) [i.e. intermittent hypoxia-exposed rat model].
- Translational research using focused therapeutic tool compounds such as various antioxidants including pure EGCG (the major catechin in Chinese green tea) in human primary cells and then to various rodent models in vivo to identify new targets and pathways.
- Examining the cellular mechanisms of adipokine and serotonin function in chronic airway diseases.
Also Cited As:
Mak, JC
Mak, J
Professional Qualifications
| Year | Awarding Institution | Qualification |
|---|---|---|
| 1985 | University of London | BSc |
| 1992 | University of London | PhD |
Biography
Dr. Judith Mak is currently Principal Lecturer of Department of Pharmacology and Pharmacy. She received her degree in Pharmacology (BSc) from The University of London in the UK. She then completed her PhD in localization of lung receptors (‘Localization of some pharmacological receptors in human and animal lung’) at the University of London under the supervision of Professor Peter J. Barnes. Following her postdoctoral training and Lecturership in the research areas for the treatment of chronic obstructive lung diseases at the National Heart & Lung Institute of Imperial College London, she returned to Hong Kong in 2002 and joined the Department of Medicine, University of Hong Kong, where she went through the ranks of Research Assistant Professor, Assistant Professor and Associate Professor before becoming Principal Lecturer. Her research interest is mainly focused on cellular and molecular mechanisms of asthma and chronic obstructive pulmonary disease (COPD), understanding and developing therapies. Her major research contributions have been in the understanding of the development of b2-agonist tolerance, and the interaction between glucocorticoid receptors and b2-adrenoceptors in the intracellular signaling pathways leading to the combination therapy of long-acting inhaled b2-agonist and inhaled glucocorticoid (e.g. SymbicortÒ and SeretideÒ). She is an internationally recognized scientist in the respiratory field. She has collaborated with academic researchers, both locally and internationally on cross-disciplinary projects. She is the principal investigator and co-investigator of a number of research projects funded by RGC, HMRF and NSFC.
Honours, Awards & Prizes
| Awardees | Award Date | Honours / Awards / Prizes | Category |
|---|---|---|---|
Chan, MMW Ho, SP | 2007-02-01 | Best Poster - Increased oxidative stress in acute asthma exacerbation in Hong Kong Chinese asthmatics: 12th Medical Research Conference | Research Achievement |
CHEN, Rui Yeung, SC Liang, Y | 2020-05-01 | 2020 International Trainee Scholarship (ITS): American Thoracic Society | Research Achievement |
LI, Xiang LIANG, Yingmin ZHEN, Zhe Zhang, Y Yeung, SC | 2014-10-01 | 3rd Prize for Outstanding Oral Presentation: Journal of the Hong Kong College of Cardiology ISSN: 1027-7811 | Research Achievement |
LI, Xiang Zhang, Y LIANG, Yingmin ZHEN, Zhe Yeung, SC | 2014-11-01 | Outstanding Oral presentation - Amelioration of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells: 18th Annual Scientific Meeting of Institute of Cardiovascular Science and Medicine | Research Achievement |
Lam, WK Cho, CH So, HL Chan, MMW Hui, WS Ho, SP | 2007-02-01 | Best Poster - Systemic oxidative stress and inflammation in cigarette smoke-exposed rat model: 12th Medical Research Conference | Research Achievement |
Lam, WK Tsang, KWT Chan, MMW Leung, CM Ho, SP Law, KW | 2005-08-01 | Best Poster - Genetic Susceptibility Of Transforming Growth Factor-beta1 Common Polymorphisms To Chinese Patients With Asthma: Hong Kong Allergy Convention 2005 | Research Achievement |
CHEN, Rui Yeung, SC | 2019-05-01 | 2019 China International Development Award: American Thoracic Society (ATS) and International Society of Respiratory Diseases (ISRD) | Research Achievement |
CUI, Yuting Lau, KWW Liu, WKK | 2016-05-01 | International Trainee Scholarship Award for 2016 International Conference: American Thoracic Society (ATS) | Research Achievement |
Zhang, Y LI, Xiang | 2015-12-01 | Poster Presentation Award at the 20th Research Postgraduate Symposium: The University of Hong Kong, Faculty of Medicine | Research Achievement |
LI, Xiang Zhang, Y LIANG, Yingmin Yeung, SC | 2014-05-01 | Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage: ATS 2014 International Conference | Research Achievement |
LIANG, Yingmin CUI, Yuting | 2015-03-01 | Travel Award - Effects of epigallocatechin gallate on cigarette smoke-induced oxidative stress and apoptosis in rat lung in vivo: Airway Vista 2015 | Research Achievement |
WANG, Yan Lee, YKM | 2016-05-01 | International Trainee Scholarship Award for 2016 International Conference: American Thoracic Society (ATS) | Research Achievement |
CUI, Yuting Liu, WKK | 2017-02-01 | Best Oral Presentation Award on Basic Science: Hong Kong Medical Journal ISSN: 1024-2708 ; eISSN: 2226-8707 | Research Achievement |
Liang, Y | 2016-10-01 | The 3rd Prize for Outstanding Poster Presentation: Journal of the Hong Kong College of Cardiology ISSN: 1027-7811 | Research Achievement |
LIANG, Yingmin Yeung, SC | 2012-12-01 | Best Poster: The 17th Congress of the Asian Pacific Society of Respirology | Research Achievement |
Liang, Y | 2018-07-01 | Congress Bursary for 18th World Congress of Basic And Clinical Pharmacology (WCP2018): 18th World Congress of Basic And Clinical Pharmacology | Research Achievement |
LIANG, Yingmin Yeung, SC | 2012-12-01 | Best Poster - Cigarette smoke induces differential alteration of AMP-activated protein kinase (AMPK) in rat heart: 17th Congress of the Asian Pacific Society of Respirology (APSR) | Research Achievement |
Professional Societies
| Term Period | Position | Professional Societies |
|---|---|---|
| 2005-present | Assoicate Member | Hong Kong Institute of Allergy |
| 2002-present | Ordinary Member | Hong Kong Pharmacological Society |
| 1993-present | Ordinary Member | British Association for Lung Research |
| 1993-present | Ordinary Member | British Pharmacological Society |
| 1997-present | Ordinary Member | Biochemical Society |
| 2023-present | Associate Member | Asian Pacific Society of Respirology (APSR) |
| 2007-present | Ordinary Member | American Thoracic Society (ATS) |
| 2002-present | Assoicate Member | Hong Kong Thoracic Society (HKTS) |
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