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Conference Paper: Effects of chronic ocular hypertension on microstructural integrity of the visual system using diffusion tensor MRI
Title | Effects of chronic ocular hypertension on microstructural integrity of the visual system using diffusion tensor MRI |
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Authors | |
Issue Date | 2014 |
Publisher | ISMRM-ESMRMB 2014. |
Citation | The 2014 joint ISMRM-ESMRMB Annual Meeting, Milano, Italy, 10-16 May 2014. How to Cite? |
Abstract | Glaucoma is a slow, irreversible neurodegenerative disease of the visual system, whose disease mechanisms are still poorly understood. Using a mouse model of laser-induced chronic ocular hypertension mimicking chronic glaucoma in humans, this study applied diffusion tensor imaging (DTI) to study the microstructural integrity spatially along the visual pathways. The results appeared to indicate the involvement of Wallerian-like anterograde degeneration as a candidate of the disease mechanisms of chronic ocular hypertension in the brain, with different progressive rates of neurodegenerative events occurring along the visual pathways. |
Description | Electronic Poster Session - Neuro 1: Animal Models of Brain: no. 3491 ISMRM Merit Award: Magna cum Laude |
Persistent Identifier | http://hdl.handle.net/10722/204152 |
DC Field | Value | Language |
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dc.contributor.author | Ho, LC | en_US |
dc.contributor.author | Yun, H | en_US |
dc.contributor.author | Kim, SG | en_US |
dc.contributor.author | Wu, EX | en_US |
dc.contributor.author | Du, Y | en_US |
dc.contributor.author | Chan, KC | en_US |
dc.date.accessioned | 2014-09-19T20:07:02Z | - |
dc.date.available | 2014-09-19T20:07:02Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | The 2014 joint ISMRM-ESMRMB Annual Meeting, Milano, Italy, 10-16 May 2014. | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/204152 | - |
dc.description | Electronic Poster Session - Neuro 1: Animal Models of Brain: no. 3491 | - |
dc.description | ISMRM Merit Award: Magna cum Laude | - |
dc.description.abstract | Glaucoma is a slow, irreversible neurodegenerative disease of the visual system, whose disease mechanisms are still poorly understood. Using a mouse model of laser-induced chronic ocular hypertension mimicking chronic glaucoma in humans, this study applied diffusion tensor imaging (DTI) to study the microstructural integrity spatially along the visual pathways. The results appeared to indicate the involvement of Wallerian-like anterograde degeneration as a candidate of the disease mechanisms of chronic ocular hypertension in the brain, with different progressive rates of neurodegenerative events occurring along the visual pathways. | - |
dc.language | eng | en_US |
dc.publisher | ISMRM-ESMRMB 2014. | - |
dc.relation.ispartof | ISMRM-ESMRMB Annual Meeting 2014 | en_US |
dc.title | Effects of chronic ocular hypertension on microstructural integrity of the visual system using diffusion tensor MRI | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Wu, EX: ewu1@hkucc.hku.hk | en_US |
dc.identifier.authority | Wu, EX=rp00193 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.hkuros | 240624 | en_US |
dc.publisher.place | Italy | en_US |